RELA - RELA proto-oncogene, NF-kB subunit Gene

Also Known as p65; CMCU; NFKB3

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 5970

About RELA

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:65,653,601-65,662,916 (from NCBI)

This gene has 26 transcripts (splice variants), 200 orthologues, 4 paralogues and is associated with 4 phenotypes. Ubiquitous expression in bone marrow (RPKM 28.6), spleen (RPKM 25.4) and 25 other tissues.

Summary

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RelB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

RELA Products (14)

mRNA	Protein	Name
XM_011545206.3	XP_011543508.1	transcription factor p65 isoform X2
NM_001404662.1	NP_001391591.1	transcription factor p65 isoform p65 iso 5
NM_021975.4	NP_068810.3	transcription factor p65 isoform 1
NM_001404658.1	NP_001391587.1	transcription factor p65 isoform 6
NM_001404657.1	NP_001391586.1	transcription factor p65 isoform 5
NM_001145138.2	NP_001138610.1	transcription factor p65 isoform 2
NM_001404660.1	NP_001391589.1	transcription factor p65 isoform 8
NM_001243984.2	NP_001230913.1	transcription factor p65 isoform 3
XM_047427392.1	XP_047283348.1	transcription factor p65 isoform X1
NM_001404661.1	NP_001391590.1	transcription factor p65 isoform 9
NM_001404659.1	NP_001391588.1	transcription factor p65 isoform 7
NM_001243985.2	NP_001230914.1	transcription factor p65 isoform 4
XM_011545207.3	XP_011543509.1	transcription factor p65 isoform X3
NM_001404663.1	NP_001391592.1	transcription factor p65 isoform p65 iso 5

RELA Protein Structure

RHD_DNA_bind

0
100
200
300
400
500
551 a.a.

Protein Preferred Names	Protein Names
transcription factor p65	NF-kappa-B p65delta3 NF-kappa-B transcription factor p65 nuclear factor NF-kappa-B p65 subunit nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 v-rel avian reticuloendotheliosis viral oncogene homolog A

RELA Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	RELA	Q04206	SNAI1	Homo sapiens	O95863	IF	19411070
Intra	RELA	Q04206	SNAI1	Homo sapiens	O95863	Anti Bait CoIP	25314079
Intra	RELA	Q04206	SNAI1	Homo sapiens	O95863	Anti Tag CoIP	25314079
Intra	RELA	Q04206	SETD7	Homo sapiens	Q8WTS6	Methyltransferase Ass	19864627
Intra	RELA	Q04206	SETD7	Homo sapiens	Q8WTS6	Methyltransferase Ass	19262565
Intra	RELA	Q04206	SETD7	Homo sapiens	Q8WTS6	Anti Tag CoIP	19262565
Intra	RELA	Q04206	COMMD1	Homo sapiens	Q8N668	Confocal	14685242
Intra	RELA	Q04206	COMMD1	Homo sapiens	Q8N668	Anti Bait CoIP	14685242
Intra	RELA	Q04206	COMMD1	Homo sapiens	Q8N668	Pull Down	15799966
Cross	RELA	Q04206	Myocd	Mus musculus	Q8VIM5-1	Anti Tag CoIP	18296632
Intra	RELA	Q04206	NR4A1	Homo sapiens	P22736-1	Anti Tag CoIP	25822914
Intra	RELA	Q04206	IER3	Homo sapiens	P46695	Pull Down	18191642
Intra	RELA	Q04206	IER3	Homo sapiens	P46695	Anti Bait CoIP	18191642
Intra	RELA	Q04206	SIRT1	Homo sapiens	Q96EB6	Anti Tag CoIP	15152190
Intra	RELA	Q04206	SIRT1	Homo sapiens	Q96EB6	Deacetylase Assay	15152190
Intra	RELA	Q04206	SIRT1	Homo sapiens	Q96EB6	Deacetylase Assay	21081649
Cross	RELA	Q04206	a0a2u2h0y9_yerpe	Yersinia pestis	A0A2U2H0Y9	Y2H Array	21911467
Cross	RELA	Q04206	a0a384kl23_yerpe	Yersinia pestis	A0A384KL23	Y2H Array	21911467
Cross	RELA	Q04206	yerA	Yersinia pestis	P31491	Y2H Array	21911467
Cross	RELA	Q04206	sctL	Yersinia pestis	P69976	Y2H Array	21911467
Intra	RELA	Q04206	NSD1	Homo sapiens	Q96L73	Anti Bait CoIP	20080798
Intra	RELA	Q04206	TP53BP2	Homo sapiens	Q13625-2	Y2H	10498867
Intra	RELA	Q04206	TP53BP2	Homo sapiens	Q13625-2	Pull Down	10498867
Intra	RELA	Q04206	TP53BP2	Homo sapiens	Q13625-2	Confocal	10498867
Intra	RELA	Q04206	NFKB1	Homo sapiens	P19838	Y2H	10498867
Intra	RELA	Q04206	NFKB1	Homo sapiens	P19838	Y2H	21988832
Intra	RELA	Q04206	NFKB1	Homo sapiens	P19838	Anti Bait CoIP	21483817
Intra	RELA	Q04206	NFKB1	Homo sapiens	P19838	Pull Down	15799966
Intra	RELA	Q04206	NFKB1	Homo sapiens	P19838	Anti Tag CoIP	35271311
Intra	RELA	Q04206	NFKB1	Homo sapiens	P19838	Y2H Array	21988832
Intra	RELA	Q04206	HDAC1	Homo sapiens	Q13547	Anti Bait CoIP	11931769
Intra	RELA	Q04206	HDAC1	Homo sapiens	Q13547	Pull Down	11931769
Intra	RELA	Q04206	HDAC1	Homo sapiens	Q13547	Anti Bait CoIP	16291753
Intra	RELA	Q04206	PPP2R1A	Homo sapiens	P30153	Pull Down	11591705
Intra	RELA	Q04206	REL	Homo sapiens	Q04864	Y2H	10498867
Intra	RELA	Q04206	REL	Homo sapiens	Q04864	Anti Tag CoIP	35271311
Intra	RELA	Q04206	NFKBIA	Homo sapiens	P25963	Anti Tag CoIP	24634218
Intra	RELA	Q04206	NFKBIA	Homo sapiens	P25963	Anti Bait CoIP	16683270
Intra	RELA	Q04206	NFKBIA	Homo sapiens	P25963	RNA-IP	25759022
Intra	RELA	Q04206	NFKBIA	Homo sapiens	P25963	Y2H	10498867
Intra	RELA	Q04206	NFKBIA	Homo sapiens	P25963	Anti Bait CoIP	14685242
Intra	RELA	Q04206	NFKBIA	Homo sapiens	P25963	Anti Bait CoIP	25609694
Intra	RELA	Q04206	NFKBIA	Homo sapiens	P25963	Y2H	21988832
Intra	RELA	Q04206	NFKBIA	Homo sapiens	P25963	Anti Bait CoIP	16951195
Intra	RELA	Q04206	NFKBIA	Homo sapiens	P25963	Pull Down	15799966
Intra	RELA	Q04206	NFKBIA	Homo sapiens	P25963	Ub Reconstruction	17612295
Intra	RELA	Q04206	UBC	Homo sapiens	P0CG48	Pull Down	17183367
Intra	RELA	Q04206	UBC	Homo sapiens	P0CG48	Anti Tag CoIP	19262565
Intra	RELA	Q04206	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	RELA	Q04206	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	RELA	Q04206	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Intra	RELA	Q04206	RPS3	Homo sapiens	P23396	Pull Down	18045535
Intra	RELA	Q04206	RPS3	Homo sapiens	P23396	Anti Tag CoIP	18045535
Intra	RELA	Q04206	RPS3	Homo sapiens	P23396	TAP	18045535
Intra	RELA	Q04206	RPS3	Homo sapiens	P23396	Anti Bait CoIP	26526615
Intra	RELA	Q04206	RPS3	Homo sapiens	P23396	Anti Bait CoIP	18045535
Intra	RELA	Q04206	GSN	Homo sapiens	P06396	Y2H Array	32814053
Intra	RELA	Q04206	GSN	Homo sapiens	P06396	Validated Y2H	32814053
Intra	RELA	Q04206	GSN	Homo sapiens	P06396	Y2H Pooling	32814053
Intra	RELA	Q04206	DHX9	Homo sapiens	Q08211	Y2H	15355351
Intra	RELA	Q04206	NFKBIB	Homo sapiens	Q15653	Y2H	10498867
Intra	RELA	Q04206	NFKBIB	Homo sapiens	Q15653	Anti Tag CoIP	35271311
Intra	RELA	Q04206	NFKBIB	Homo sapiens	Q15653	Y2H	21988832
Intra	RELA	Q04206	NFKBIB	Homo sapiens	Q15653	Anti Bait CoIP	14685242
Intra	RELA	Q04206	NFKBIE	Homo sapiens	O00221	Anti Tag CoIP	35271311
Intra	RELA	Q04206	NFKBIE	Homo sapiens	O00221	Y2H Array	21988832
Intra	RELA	Q04206	NFKBIE	Homo sapiens	O00221	Y2H	21988832
Intra	RELA	Q04206	UXT	Homo sapiens	Q9UBK9	Anti Tag CoIP	17620405
Intra	RELA	Q04206	UXT	Homo sapiens	Q9UBK9	Y2H	17620405
Cross	RELA	Q04206	P/V	measles virus	P0C774	Pull Down	21270162
Cross	RELA	Q04206	P/V	measles virus	P0C774	Anti Tag CoIP	21270162
Intra	RELA	Q04206	AATF	Homo sapiens	Q9NY61	Anti Tag CoIP	17157788
Intra	RELA	Q04206	AATF	Homo sapiens	Q9NY61	Anti Bait CoIP	17157788
Intra	RELA	Q04206	TARDBP	Homo sapiens	Q13148	Anti Bait CoIP	24690380
Intra	RELA	Q04206	TARDBP	Homo sapiens	Q13148	IF	24690380
Intra	RELA	Q04206	IRF5	Homo sapiens	Q13568	Anti Bait CoIP	20237317
Intra	RELA	Q04206	IRF5	Homo sapiens	Q13568	Anti Tag CoIP	25159141
Intra	RELA	Q04206	IRF5	Homo sapiens	Q13568	Anti Tag CoIP	20237317
Intra	RELA	Q04206	SIRT2	Homo sapiens	Q8IXJ6	Deacetylase Assay	21081649
Intra	RELA	Q04206	CTNNB1	Homo sapiens	P35222	Anti Bait CoIP	23273993
Intra	RELA	Q04206	STAT3	Homo sapiens	P40763	Confocal	19345327
Intra	RELA	Q04206	STAT3	Homo sapiens	P40763	Anti Bait CoIP	19345327
Intra	RELA	Q04206	MACROD1	Homo sapiens	Q9BQ69	Anti Bait CoIP	21483817
Intra	RELA	Q04206	MACROD1	Homo sapiens	Q9BQ69	Confocal	21483817
Intra	RELA	Q04206	MACROD1	Homo sapiens	Q9BQ69	Pull Down	21483817
Cross	RELA	Q04206	Brd4	Mus musculus	Q9ESU6	Anti Tag CoIP	19103749
Cross	RELA	Q04206	Brd4	Mus musculus	Q9ESU6	Pull Down	19103749
Intra	RELA	Q04206	P19838-PRO_0000030311	Homo sapiens	P19838-PRO_0000030311	Anti Bait CoIP	22808155
Intra	RELA	Q04206	P19838-PRO_0000030311	Homo sapiens	P19838-PRO_0000030311	Anti Tag CoIP	24634218
Intra	RELA	Q04206	PPP2CA	Homo sapiens	P67775	Phosphatase Assay	11591705
Intra	RELA	Q04206	PPP2CA	Homo sapiens	P67775	Pull Down	11591705
Intra	RELA	Q04206	PPP2CA	Homo sapiens	P67775	Crosslink	11591705
Intra	RELA	Q04206	SIRT6	Homo sapiens	Q8N6T7	Anti Bait CoIP	19135889
Intra	RELA	Q04206	SIRT6	Homo sapiens	Q8N6T7	Pull Down	19135889
Intra	RELA	Q04206	SIRT6	Homo sapiens	Q8N6T7	Anti Tag CoIP	19135889
Intra	RELA	Q04206	MAPK10	Homo sapiens	P53779	Y2H	21988832
Intra	RELA	Q04206	KLF6	Homo sapiens	Q99612	Anti Bait CoIP	24634218
Intra	RELA	Q04206	KLF6	Homo sapiens	Q99612	Anti Tag CoIP	24634218
Intra	RELA	Q04206	CDK5RAP3	Homo sapiens	Q96JB5	Pull Down	17785205
Intra	RELA	Q04206	CDK5RAP3	Homo sapiens	Q96JB5	Anti Bait CoIP	17785205
Intra	RELA	Q04206	BRD4	Homo sapiens	O60885	Pull Down	23686307
Intra	RELA	Q04206	BRD4	Homo sapiens	O60885	Anti Tag CoIP	23686307
Intra	RELA	Q04206	BRD4	Homo sapiens	O60885	X-Ray Diffraction	23686307
Intra	RELA	Q04206	TGM2	Homo sapiens	P21980	Anti Bait CoIP	16951195
Intra	RELA	Q04206	LMO2	Homo sapiens	P25791	Y2H	21988832
Intra	RELA	Q04206	KDM2A	Homo sapiens	Q9Y2K7	Anti Bait CoIP	20080798
Intra	RELA	Q04206	EHMT1	Homo sapiens	Q9H9B1	Anti Bait CoIP	21131967
Intra	RELA	Q04206	DAXX	Homo sapiens	Q9UER7	Anti Bait CoIP	17362989
Intra	RELA	Q04206	DAXX	Homo sapiens	Q9UER7	Confocal	17362989
Intra	RELA	Q04206	DAXX	Homo sapiens	Q9UER7	Anti Tag CoIP	17362989
Intra	RELA	Q04206	ESR1	Homo sapiens	P03372	Anti Bait CoIP	19350539
Intra	RELA	Q04206	ESR1	Homo sapiens	P03372	Anti Bait CoIP	17932106
Intra	RELA	Q04206	ESR1	Homo sapiens	P03372	Pull Down	19350539
Intra	RELA	Q04206	ESR1	Homo sapiens	P03372	Pull Down	7651415
Intra	RELA	Q04206	ESR1	Homo sapiens	P03372	Pull Down	17932106
Intra	RELA	Q04206	CREBBP	Homo sapiens	Q92793	Anti Bait CoIP	16291753
Intra	RELA	Q04206	CREBBP	Homo sapiens	Q92793	Anti Bait CoIP	21483817
Intra	RELA	Q04206	CREBBP	Homo sapiens	Q92793	Pull Down	16291753
Intra	RELA	Q04206	CHUK	Homo sapiens	O15111	Anti Tag CoIP	35271311
Intra	RELA	Q04206	IKBKB	Homo sapiens	O14920	PLA	25241761
Intra	RELA	Q04206	IKBKB	Homo sapiens	O14920	Anti Tag CoIP	35271311
Intra	RELA	Q04206	PDCD4	Homo sapiens	Q53EL6	Anti Tag CoIP	24413684
Intra	RELA	Q04206	PDCD4	Homo sapiens	Q53EL6	Confocal	24413684
Intra	RELA	Q04206	GFI1	Homo sapiens	Q99684	Anti Bait CoIP	20547752
Intra	RELA	Q04206	ATF3	Homo sapiens	P18847-3	Pull Down	16291753
Intra	RELA	Q04206	ATF3	Homo sapiens	P18847-3	Anti Bait CoIP	16291753
Intra	RELA	Q04206	MEN1	Homo sapiens	O00255-2	Pull Down	11526476
Cross	RELA	Q04206	pap_hhv11	Human herpesvirus 1	P10226	Anti Tag CoIP	23636254
Cross	RELA	Q04206	b3ctb0_oriti	Orientia tsutsugamushi	B3CTB0	Anti Tag CoIP	29734393
Cross	RELA	Q04206	b3crr2_oriti	Orientia tsutsugamushi	B3CRR2	Anti Tag CoIP	29734393

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant RELA Proteins

Cat. No.	Product Name	Accession	Purity
HY-P73681	RelA/NFkB p65 Protein, Human (GST)	Q04206-1 (M1-Y306)	≥ 95%, as determined by reducing SDS-PAGE.

RELA Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80245	NF-KB p65 Antibody (YA267)	WB, ICC/IF, IHC-P, IP, FC	Human, Mouse
HY-P80470	Phospho-NF-κB p65 (Ser529) Antibody (YA170)	WB, IP, FC, IHC-P	Human
HY-P80765	NF-KB p65 Antibody (YA268)	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse
HY-P80839	Phospho-NF-KB p65 (Ser536) Antibody	WB, IHC-P, ICC/IF	Human, Mouse, Rat
HY-P80840	Phospho-NF-KB p65 (Thr254) Antibody	WB, IHC-P, ICC/IF	Human, Mouse, Rat
HY-P81238	Phospho-NF-κB p65 (Ser536) Antibody	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat, Monkey
HY-P84479	NF-κB p65 Antibody (YA4176)	WB, IHC-P, ELISA	Human, Mouse, Rat, Rabbit, Monkey
HY-P84479A	NF-κB p65 Antibody (YA4176)(PBS only)	WB, IHC-P, ELISA	Human, Mouse, Rat, Rabbit, Monkey
HY-P85677	NFkB p65 Antibody (YA5369)	WB, ICC/IF, ELISA	Human, Mouse,
HY-P86492	NF-κB p65 Antibody (YA6184)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
HY-P86687	NF-KB p65 Antibody (YA6379)	WB, IHC-P, IHC-F, IF-Tissue	Human, Mouse, Rat
HY-P86720	NF-KB p65 Antibody (YA6412)	WB, IHC-P, IHC-F, ICC/IF	Human, Mouse, Rat
HY-P86720A	NF-KB p65 Antibody (YA6412)(PBS only)	WB, IHC-P, IHC-F, ICC/IF	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Mucocutaneous Ulceration, Chronic	CMCU
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Benign Ependymoma	Ependymoma Epithelial Ependymoma Who Grade Ii Ependymal Tumor Myxopapillary Ependymoma
Sweeney-Cox Syndrome	SWCOS
Pancreatic Adenocarcinoma	Adenocarcinoma Of Pancreas Adenocarcinoma Of The Pancreas Pancreas Adenocarcinoma Malignant Exocrine Neoplasm Primary Pancreatic Adenocarcinoma Adenocarcinoma Of Islet Cell Of Pancreas Islet Cell Adenocarcinoma Of Unspecified Site Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site
Central Nervous System Germ Cell Tumor	Central Nervous System Germ Cell Tumour Germ Cell Tumor Of The Cns Germ Cell Tumour Of The Cns
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
High Grade Ependymoma	Ependymal Neoplasm Ependymal Tumors Malignant Ependymoma Ependymal Tumor Anaplastic Ependymoma Experimental Organism Malignant Ependymoma Ependymoma Of Brain
Reticuloendotheliosis, X-Linked	Reticuloendotheliosis
Autoinflammatory Syndrome, Familial, Behcet-Like 1	Autoinflammatory Syndrome, Familial, Behcet-Like AIFBL1 Aifbl Hereditary Pediatric Behcet-Like Disease Behcet-Like Disease Due To Ha20 Behcet-Like Disease Due To Haploinsufficiency Of A20 AISBL
Rela Fusion-Positive Ependymoma	Supratentorial C11orf95-Rela Fused Ependymoma C11orf95 Fusion-Positive Supratentorial Ependymoma
Hypersplenism	Hypersplenia Big Spleen Syndrome Hyperfunction Of Spleen Increased Splenic Activity Spleen Metaplasia Splenic Metaplasia
Childhood Ependymoma
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Glottis Squamous Cell Carcinoma	Epidermoid Carcinoma Of The Glottis Squamous Cell Carcinoma Of Glottis
Cerebral Ventricle Cancer	Cerebral Ventricle Neoplasms Cerebral Ventricle Neoplasm Intraventricular Tumor Of Brain
Astroblastoma	Cerebral Astroblastoma
Covid-19	2019 Novel Coronavirus 2019-Ncov Infection Covid19 Sars-Cov-2 Infection Wuhan Coronavirus Infection Wuhan Seafood Market Pneumonia Virus Infection
Anaplastic Ependymoma	Ependymoma, Anaplastic Undifferentiated Ependymoma
Tanycytic Ependymoma
B-Cell Lymphoma	Lymphoma, B-Cell B-Cell Lymphomas B-Cell Lymphocytic Neoplasm Lymphoma B-Cell B-Cell Lymphoma Nos
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Protection Against Lung Cancer, Susceptibility To Adenocarcinoma Of Lung, Somatic Nonsmall Cell Lung Cancer Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Clear Cell Ependymoma	Cellular Ependymoma
Supratentorial Ependymoma
Adenocarcinoma	Adenocarcinomas Adenoacanthoma Of Unspecified Site Adenocarcinoid Of Unspecified Site Adenocarcinoid Tumour Of Unspecified Site Adenocarcinoma And Carcinoid Combined Of Unspecified Site Adenocarcinoma Nos
Inhibited Male Orgasm	Male Orgasmic Disorder Psychosexual Dysfunction With Male Orgasmic Disorder
Cellular Ependymoma	Ependymoma Classic Ependymoma Papillary Ependymoma Tanycytic Ependymoma Clear Cell Ependymoma Ependymoma, Familial Epithelial Ependymoma Who Grade Ii Ependymal Neoplasm
Myxopapillary Ependymoma	Ependymoma Myxopapillary
Rabies	Lyssa Hydrophobia St Hubert Disease
Spinal Cord Ependymoma	Ependymal Neoplasm Of The Spinal Cord Ependymoma Of Spinal Cord
Supratentorial Cancer	Supratentorial Neoplasms Brain Neoplasm, Supratentorial Malignant Supratentorial Tumor Cancer, Supratentorial
Cerebrum Cancer	Cerebral Cancer Neoplasm Of Cerebrum Tumor Of Cerebrum Malignant Neoplasm Of Cerebrum
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Childhood-Onset Schizophrenia	Childhood Schizophrenia Schizophrenia, Childhood
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Childhood Supratentorial Ependymoma	Paediatric Cerebral Ependymoma Paediatric Supratentorial Ependymoblastoma Paediatric Supratentorial Ependymoma Pediatric Cerebral Ependymoma Pediatric Supratentorial Ependymoblastoma Pediatric Supratentorial Ependymoma
Atypical Teratoid Rhabdoid Tumor	Rhabdoid Tumor Predisposition Syndrome Rtps Atypical Teratoid/Rhabdoid Tumor Rhabdoid Predisposition Syndrome Familial Posterior Fossa Brain Tumor Of Infancy Familial Rhabdoid Tumor At/Rt Atypical Teratoid Rhabdoid Tumour Atypical Teratoid/Rhabdoid Tumour Rhabdoid Tumor Of The Cns Rhabdoid Tumour Of The Cns Familial Posterior Fossa Brain Tumor Syndrome Hereditary Swi/Snf Deficiency Syndrome Atrt
Posterior Fossa Ependymoma
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Disease Primary Immunodeficiency Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Myofibroma	Lipoleiomyoma Uterine Fibroids Solitary Myofibromatosis Myolipoma
Molluscum Contagiosum	Water Warts Molluscum Verrucosum
Retinitis Pigmentosa 35	RP35 Retinitis Pigmentosa-35 Retinitis Pigmentosa, Type 35

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-170316	Ibetazol	Inhibitor	99.80%	Unkown
HY-174864	JP-163-16		99.20%	Unkown
HY-N2441	Methylophiopogonone A	Inhibitor	99.84%	Unkown
HY-N7043	Isosilybin A		99.63%	Unkown
HY-RS11827	Rela Mouse Pre-designed siRNA Set A		/	Unkown
HY-121309	Doxorubicinone	Inhibitor	98.29%	Unkown
HY-RS11826	RELA Human Pre-designed siRNA Set A		/	Unkown
HY-101512D	rel-A-395 hydrochloride	Inhibitor	/	Unkown
HY-174865	MMH-165-26		/	Unkown
HY-RS11828	Rela Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	RELA	RGD	RGD:727889
Bos taurus	RELA	VGNC	VGNC:33858
Macaca mulatta	RELA	VGNC	VGNC:76893
Mus musculus	RELA	MGD	MGI:103290
Canis familiaris	RELA	VGNC	VGNC:45466
Felis catus	RELA	VGNC	VGNC:69283
Others	RELA	NCBI