1. Apoptosis
  2. Apoptosis
  3. Isosilybin A

Isosilybin A 

Cat. No.: HY-N7043 Purity: >99.0%
Handling Instructions

Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis.

For research use only. We do not sell to patients.

Isosilybin A Chemical Structure

Isosilybin A Chemical Structure

CAS No. : 142796-21-2

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10 mM * 1 mL in DMSO USD 265 In-stock
Estimated Time of Arrival: December 31
1 mg USD 100 In-stock
Estimated Time of Arrival: December 31
5 mg USD 250 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Isosilybin A, a flavonolignan isolated from silymarin, has anti-prostate cancer (PCA) activity. Isosilybin A inhibits proliferation and induces G1 phase arrest and apoptosis in cancer cells, which activates apoptotic machinery in PCA cells via targeting Akt-NF-κB-androgen receptor (AR) axis[1][2].

Molecular Weight

482.44

Formula

C₂₅H₂₂O₁₀

CAS No.

142796-21-2

SMILES

O=C1[[email protected]](O)[[email protected]@H](C2=CC=C(O[[email protected]](C3=CC=C(O)C(OC)=C3)[[email protected]@H](CO)O4)C4=C2)OC5=CC(O)=CC(O)=C15

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

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Isosilybin A
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HY-N7043
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