UXT - ubiquitously expressed prefoldin like chaperone Gene

Homo sapiens

Also known as STAP1; ART-27

Gene ID: 8409 | Gene type: protein coding

About UXT

Cytogenetic location: Xp11.23 Genomic coordinates (GRCh38): X:47,651,796-47,659,180 (from NCBI)

This gene has 5 transcripts (splice variants) and 181 orthologues. Ubiquitous expression in bone marrow (RPKM 37.8), ovary (RPKM 37.2) and 25 other tissues.

Summary

The protein encoded by this gene functions as a cofactor that modulates androgen receptor-dependent transcription, and also plays a critical role in tumor necrosis factor-induced Apoptosis. Expression of this gene may play a role in tumorigenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

UXT Products(2)

mRNA	Protein	Name
NM_004182.4	NP_004173.1	protein UXT isoform 2
NM_153477.3	NP_705582.1	protein UXT isoform 1

UXT Protein Structure

Prefoldin

0
100
157 a.a.

Protein Preferred Names

Protein Names

protein UXT

SKP2-associated alpha PFD 1

Related Diseases

Diseases

Alias

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15591	UXT Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	UXT	VGNC	VGNC:36754
Felis catus	UXT	VGNC	VGNC:66910
Rattus norvegicus	UXT	RGD	RGD:1359326
Macaca mulatta	UXT	VGNC	VGNC:103884
Canis familiaris	UXT	VGNC	VGNC:48221
Mus musculus	UXT	MGD	MGI:1277988