C2CD6 - C2 calcium dependent domain containing 6 Gene

Also Known as SPGF68; ALS2CR11

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 151254

Summary

An autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes this gene. The encoded protein contains a calcium-dependent membrane targeting C2 domain. This domain is often found in proteins that are involved in membrane trafficking and signal transduction. [provided by RefSeq, Jun 2016]

C2CD6 Products (1)

mRNA Protein Name
XR_008486293.1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Cellular Component GO Annotation Evidence References Source
located in sperm principal piece IDA
IDA: Inferred from direct assay
34998468 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cation channel sperm-associated targeting subunit tau

  • C2 calcium-dependent domain-containing protein 6

  • amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11

  • amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein

  • amyotrophic lateral sclerosis 2 chromosome region c

C2CD6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
C2CD6 Q53TS8 KRT13 Homo sapiens A1A4E9
Y2H Array
25416956
Intra
C2CD6 Q53TS8 KRT40 Homo sapiens Q6A162
Y2H Array
25416956
Intra
C2CD6 Q53TS8 CCDC57 Homo sapiens Q2TAC2-2
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 CCDC57 Homo sapiens Q2TAC2-2
Y2H Array
32296183
Intra
C2CD6 Q53TS8 GRAMD4 Homo sapiens Q6IC98
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 GRAMD4 Homo sapiens Q6IC98
Y2H Array
32296183
Intra
C2CD6 Q53TS8 GRAMD4 Homo sapiens Q6IC98
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 TFIP11 Homo sapiens Q9UBB9
Y2H Prey Pooling
25416956
Intra
C2CD6 Q53TS8 TFIP11 Homo sapiens Q9UBB9
Validated Y2H
25416956
Intra
C2CD6 Q53TS8 GPRASP3 Homo sapiens Q6PI77
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 GPRASP3 Homo sapiens Q6PI77
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 GPRASP3 Homo sapiens Q6PI77
Y2H Array
32296183
Intra
C2CD6 Q53TS8 AP2B1 Homo sapiens P63010-2
Y2H Array
32296183
Intra
C2CD6 Q53TS8 AP2B1 Homo sapiens P63010-2
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 TLE5 Homo sapiens Q08117-2
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 TLE5 Homo sapiens Q08117-2
Y2H Array
32296183
Intra
C2CD6 Q53TS8 CDR2 Homo sapiens Q01850
Validated Y2H
25416956
Intra
C2CD6 Q53TS8 DISC1 Homo sapiens Q9NRI5-2
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 DISC1 Homo sapiens Q9NRI5-2
Y2H Array
32296183
Intra
C2CD6 Q53TS8 DISC1 Homo sapiens Q9NRI5-2
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 LHX1 Homo sapiens P48742
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 LHX1 Homo sapiens P48742
Y2H Array
32296183
Intra
C2CD6 Q53TS8 LHX3 Homo sapiens Q9UBR4-2
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 LHX3 Homo sapiens Q9UBR4-2
Y2H Array
32296183
Intra
C2CD6 Q53TS8 LHX3 Homo sapiens Q9UBR4-2
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 ANKK1 Homo sapiens Q8NFD2
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 ANKK1 Homo sapiens Q8NFD2
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 ANKK1 Homo sapiens Q8NFD2
Y2H Array
32296183
Intra
C2CD6 Q53TS8 PIBF1 Homo sapiens Q4G0R1
Y2H Array
32296183
Intra
C2CD6 Q53TS8 PIBF1 Homo sapiens Q4G0R1
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 KIFC3 Homo sapiens Q9BVG8-5
Y2H Array
32296183
Intra
C2CD6 Q53TS8 KIFC3 Homo sapiens Q9BVG8-5
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 KIFC3 Homo sapiens Q9BVG8-5
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 JRK Homo sapiens O75564-2
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 JRK Homo sapiens O75564-2
Y2H Array
32296183
Intra
C2CD6 Q53TS8 ZNF474 Homo sapiens Q6S9Z5
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 ZNF474 Homo sapiens Q6S9Z5
Y2H Array
32296183
Intra
C2CD6 Q53TS8 ZNF474 Homo sapiens Q6S9Z5
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 ACOT11 Homo sapiens Q8WXI4-2
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 ACOT11 Homo sapiens Q8WXI4-2
Y2H Array
32296183
Intra
C2CD6 Q53TS8 ACOT11 Homo sapiens Q8WXI4-2
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 BBS4 Homo sapiens Q96RK4
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 BBS4 Homo sapiens Q96RK4
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 BBS4 Homo sapiens Q96RK4
Y2H Array
32296183
Intra
C2CD6 Q53TS8 FAM217B Homo sapiens Q9NTX9
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 FAM217B Homo sapiens Q9NTX9
Y2H Array
32296183
Intra
C2CD6 Q53TS8 FAM217B Homo sapiens Q9NTX9
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 VAC14 Homo sapiens Q08AM6
Y2H Array
32296183
Intra
C2CD6 Q53TS8 VAC14 Homo sapiens Q08AM6
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
25416956
Intra
C2CD6 Q53TS8 TRIM54 Homo sapiens Q9BYV2
Y2H Array
25416956
Intra
C2CD6 Q53TS8 MIPOL1 Homo sapiens Q8TD10
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 MIPOL1 Homo sapiens Q8TD10
Y2H Array
32296183
Intra
C2CD6 Q53TS8 MIPOL1 Homo sapiens Q8TD10
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 CCDC172 Homo sapiens P0C7W6
Y2H Array
32296183
Intra
C2CD6 Q53TS8 CCDC172 Homo sapiens P0C7W6
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 TACC3 Homo sapiens Q9Y6A5
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 TACC3 Homo sapiens Q9Y6A5
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 TACC3 Homo sapiens Q9Y6A5
Y2H Array
32296183
Intra
C2CD6 Q53TS8 CNOT11 Homo sapiens Q9UKZ1
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 CNOT11 Homo sapiens Q9UKZ1
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 CNOT11 Homo sapiens Q9UKZ1
Y2H Array
32296183
Intra
C2CD6 Q53TS8 VPS52 Homo sapiens Q8N1B4
Y2H Array
32296183
Intra
C2CD6 Q53TS8 VPS52 Homo sapiens Q8N1B4
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 VPS52 Homo sapiens Q8N1B4
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 MEOX1 Homo sapiens P50221
Y2H Array
32296183
Intra
C2CD6 Q53TS8 MEOX1 Homo sapiens P50221
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 ACTN3 Homo sapiens Q08043
Y2H Array
32296183
Intra
C2CD6 Q53TS8 ACTN3 Homo sapiens Q08043
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 KRT75 Homo sapiens O95678
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 KRT75 Homo sapiens O95678
Y2H Array
32296183
Intra
C2CD6 Q53TS8 MCRS1 Homo sapiens Q96EZ8
Y2H Array
32296183
Intra
C2CD6 Q53TS8 MCRS1 Homo sapiens Q96EZ8
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 MCRS1 Homo sapiens Q96EZ8
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
Intra
C2CD6 Q53TS8 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 RNF8 Homo sapiens O76064
Y2H Array
32296183
Intra
C2CD6 Q53TS8 RNF8 Homo sapiens O76064
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 TSSK3 Homo sapiens Q96PN8
Y2H Array
32296183
Intra
C2CD6 Q53TS8 TSSK3 Homo sapiens Q96PN8
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 TSSK3 Homo sapiens Q96PN8
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 TCP10L Homo sapiens Q8TDR4
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 TCP10L Homo sapiens Q8TDR4
Y2H Array
32296183
Intra
C2CD6 Q53TS8 TCP10L Homo sapiens Q8TDR4
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 DNAJA3 Homo sapiens Q96EY1-2
Validated Y2H
25416956
Intra
C2CD6 Q53TS8 DNAJA3 Homo sapiens Q96EY1-2
Y2H Array
25416956
Intra
C2CD6 Q53TS8 MEAF6 Homo sapiens Q9HAF1
Y2H Array
32296183
Intra
C2CD6 Q53TS8 MEAF6 Homo sapiens Q9HAF1
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 MEAF6 Homo sapiens Q9HAF1
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 GOLGA2 Homo sapiens Q08379
Y2H Array
25416956
Intra
C2CD6 Q53TS8 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
25416956
Intra
C2CD6 Q53TS8 GOLGA2 Homo sapiens Q08379
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 GOLGA2 Homo sapiens Q08379
Y2H Array
32296183
Intra
C2CD6 Q53TS8 CT55 Homo sapiens Q8WUE5
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 CT55 Homo sapiens Q8WUE5
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 CT55 Homo sapiens Q8WUE5
Y2H Array
32296183
Intra
C2CD6 Q53TS8 FHL2 Homo sapiens Q14192
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 FHL2 Homo sapiens Q14192
Y2H Array
32296183
Intra
C2CD6 Q53TS8 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra
C2CD6 Q53TS8 HAP1 Homo sapiens P54257
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 HAP1 Homo sapiens P54257
Y2H Array
32296183
Intra
C2CD6 Q53TS8 HSPB8 Homo sapiens Q9UJY1
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 HSPB8 Homo sapiens Q9UJY1
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 HSPB8 Homo sapiens Q9UJY1
Y2H Array
32296183
Intra
C2CD6 Q53TS8 KRT15 Homo sapiens P19012
Validated Y2H
25416956
Intra
C2CD6 Q53TS8 TRIM23 Homo sapiens P36406
Y2H Array
32296183
Intra
C2CD6 Q53TS8 TRIM23 Homo sapiens P36406
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 LZTS2 Homo sapiens Q9BRK4
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 LZTS2 Homo sapiens Q9BRK4
Y2H Array
32296183
Intra
C2CD6 Q53TS8 LZTS2 Homo sapiens Q9BRK4
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 CHCHD3 Homo sapiens Q9NX63
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 CHCHD3 Homo sapiens Q9NX63
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 CHCHD3 Homo sapiens Q9NX63
Y2H Array
32296183
Intra
C2CD6 Q53TS8 SPATA2 Homo sapiens Q9UM82
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 SPATA2 Homo sapiens Q9UM82
Y2H Array
32296183
Intra
C2CD6 Q53TS8 SPATA2 Homo sapiens Q9UM82
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 IKZF3 Homo sapiens Q9UKT9
Validated Y2H
32296183
Intra
C2CD6 Q53TS8 IKZF3 Homo sapiens Q9UKT9
Y2H Array
32296183
Intra
C2CD6 Q53TS8 IKZF3 Homo sapiens Q9UKT9
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 PAX6 Homo sapiens P26367
Y2H Array
32296183
Intra
C2CD6 Q53TS8 PAX6 Homo sapiens P26367
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 CARD9 Homo sapiens Q9H257
Y2H Array
25416956
Intra
C2CD6 Q53TS8 NR5A1 Homo sapiens Q13285
Y2H Prey Pooling
32296183
Intra
C2CD6 Q53TS8 NR5A1 Homo sapiens Q13285
Y2H Array
32296183
Intra
C2CD6 Q53TS8 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Intra
C2CD6 Q53TS8 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
25416956
Intra
C2CD6 Q53TS8 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01740 C2CD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01741 C2CD5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown