CNOT11 - CCR4-NOT transcription complex subunit 11 Gene

Also Known as C40; C2orf29

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55571

About CNOT11

This gene has 3 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in testis (RPKM 19.6), placenta (RPKM 16.9) and 25 other tissues.

Summary

Predicted to be involved in mRNA catabolic process and negative regulation of translation. Part of CCR4-NOT complex. [provided by Alliance of Genome Resources, Apr 2022]

CNOT11 Products (1)

mRNA Protein Name
NM_017546.5 NP_060016.3 CCR4-NOT transcription complex subunit 11

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
23232451 GOA
Cellular Component GO Annotation Evidence References Source
part of CCR4-NOT complex IDA
IDA: Inferred from direct assay
19558367 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CNOT11 Protein Structure

DUF2363

DUF2363: Uncharacterized conserved protein (DUF2363) (371 - 495)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 510 a.a.
Protein Preferred Names Protein Names

CCR4-NOT transcription complex subunit 11

  • UPF0760 protein C2orf29

CNOT11 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CNOT11 Q9UKZ1 CNOT10 Homo sapiens Q9H9A5
TAP
23232451
Intra
CNOT11 Q9UKZ1 CNOT10 Homo sapiens Q9H9A5
Y2H
23232451
Intra
CNOT11 Q9UKZ1 CNOT10 Homo sapiens Q9H9A5
Anti Tag CoIP
33961781
Intra
CNOT11 Q9UKZ1 CNOT1 Homo sapiens A5YKK6
TAP
23232451
Intra
CNOT11 Q9UKZ1 CNOT1 Homo sapiens A5YKK6
Anti Tag CoIP
33961781
Intra
CNOT11 Q9UKZ1 CNOT1 Homo sapiens A5YKK6
Y2H
23232451
Cross
CNOT11 Q9UKZ1 Cnot7 Mus musculus Q60809
Pull Down
23232451
Intra
CNOT11 Q9UKZ1 MEOX1 Homo sapiens P50221
Y2H Array
32296183
Intra
CNOT11 Q9UKZ1 MEOX1 Homo sapiens P50221
Y2H Prey Pooling
32296183
Intra
CNOT11 Q9UKZ1 FAM193B Homo sapiens Q96PV7
Y2H Prey Pooling
32296183
Intra
CNOT11 Q9UKZ1 FAM193B Homo sapiens Q96PV7
Y2H Array
32296183
Intra
CNOT11 Q9UKZ1 GPBP1L1 Homo sapiens Q9HC44
Y2H Array
32296183
Intra
CNOT11 Q9UKZ1 GPBP1L1 Homo sapiens Q9HC44
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Glioblastoma Mesenchymal Subtype
Cycloplegia

  • Ciliary Muscle Paresis

  • Cycloplegic Paralysis Of Accommodation

  • Paresis Of Accommodation

  • Visual Accommodation Paralysis

  • Accommodation Paralysis

  • Intrinsic Paralysis Of Eye Muscle

  • Cycloplegic
Eye Accommodation Disease
Lens Subluxation

  • Subluxation Of Lens
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02901 CNOT11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CNOT11 VGNC VGNC:71346
Felis catus CNOT11 VGNC VGNC:61027
Bos taurus CNOT11 VGNC VGNC:27516
Mus musculus CNOT11 MGD MGI:106580
Canis familiaris CNOT11 VGNC VGNC:39412
Rattus norvegicus CNOT11 RGD RGD:1560909
Others CNOT11 NCBI