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54540

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By Targets:	3β-HSD (1) Adenosine Receptor (1) COX (1) GLUT (1) Isotope-Labeled Compounds (2) MicroRNA (4) mTOR (1) Oxidative Phosphorylation (1) Parasite (1) Proteasome (1) Reference Standards (1)
By Research Areas:	Cancer (7) Endocrinology (3) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (1)
Oligonucleotides:	miRNA mimics (1) miRNA antagomirs (1) miRNA agomirs (1) MicroRNAs (4) miRNA inhibitors (1)

Inhibitors & Agonists

Peptides

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-14281

Trilostane 2 Publications Verification Win 24540	3β-HSD	Endocrinology Cancer
Trilostane (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane is a synthetic nonhormonal steroid. Trilostane can be used for the research of breast cancer and prostate cancer .

HY-101432

Fenclozic acid ICI-54450; Acidum fenclozicum; Mialex	COX	Inflammation/Immunology
Fenclozic acid (ICI-54450) is an orally active anti-inflammatory, analgesic, and antipyretic agent. Fenclozic acid exhibits anti-inflammatory activity in Edadjuvant-induced arthritis and Carrageenin-induced oedema in rats. Fenclozic acid can be used for the research of arthritis .

HY-129051

Amoscanate CGP4540	Parasite Oxidative Phosphorylation	Others
Amoscanate (cgp4540) is phenyl isothiocyanate in which the hydrogen at the para-position has been replaced by a 4-nitroanilinyl group. Amoscanate is an anti-schistosomal agent. Amoscanate, as an isothiocyanate compound and uncoupler of oxidative phosphorylation, potently injures rodent ependyma .

HY-101828

Guaiapate Klamar; Mg 5454	Others	Inflammation/Immunology
Guaiapate is an antitussive agent.

HY-14281R

Trilostane (Standard) Win 24540 (Standard)	Reference Standards Others	Endocrinology Cancer
Trilostane (Standard) is the analytical standard of Trilostane. This product is intended for research and analytical applications. Trilostane (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane is a synthetic nonhormonal steroid. Trilostane can be used for the research of breast cancer and prostate cancer .

HY-123038

CVT-5440	Adenosine Receptor	Inflammation/Immunology
CVT-5440 is a xanthine based, selective, high affinity A_2B adenosine receptors (AdoR) antagonist with a K_i of 50 nM (selectivity A₁> 200; A_2A>200; A₃>167). CVT-5440 has the potential for asthma research .

HY-16707

CH 5450 Z-Ile-Glu-Pro-Phe-Ome	Proteasome	Inflammation/Immunology
CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC₅₀ value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC₅₀ value of 4.8 µM .

HY-RI01168

*hsa-miR-4540* inhibitor**	MicroRNA	Cancer
hsa-miR-4540 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

hsa-miR-4540 inhibitor hsa-miR-4540 inhibitor

HY-R01168

*hsa-miR-4540* mimic**	MicroRNA	Cancer
hsa-miR-4540 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

hsa-miR-4540 mimic hsa-miR-4540 mimic

HY-14281S

Trilostane-d3 Win 24540-d₃	Isotope-Labeled Compounds	Others
Trilostane-d₃ is the deuterium-labeled Trilostane (HY-14281). Trilostane-d₃ (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane-d₃ is a synthetic nonhormonal steroid. Trilostane-d₃ can be used for the research of breast cancer and prostate cancer .

HY-14281S2

Trilostane-d3-1 Win 24540-d₃-1	Isotope-Labeled Compounds	Endocrinology
Trilostane-d₃-1 (Win 24540-d₃-1) is deuterium-labeled Trilostane (HY-14281) .

HY-138976

NV-5440	mTOR GLUT	Neurological Disease Metabolic Disease Cancer
NV-5440 (Compound I-120) is an mTORC1 inhibitor and glucose transporter inhibitor. NV-5440 targets GLUT-1, -2, -3, and -4, and shows no activity against GLUT-5. NV-5440 inhibits glucose uptake .

HY-R01168A

*hsa-miR-4540* agomir**	MicroRNA	Cancer
hsa-miR-4540 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4540 agomir hsa-miR-4540 agomir

HY-RI01168A

*hsa-miR-4540* antagomir**	MicroRNA	Cancer
hsa-miR-4540 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

hsa-miR-4540 antagomir hsa-miR-4540 antagomir

Cat. No.	Product Name	Target	Research Area

HY-16707

CH 5450 Z-Ile-Glu-Pro-Phe-Ome	Proteasome	Inflammation/Immunology
CH 5450 (Z-Ile-Glu-Pro-Phe-Ome) is a selective short peptide human cardiac chymase inhibitor. CH-5450 inhibits the action of rat MAB elastase 2 on substrate Ang I with an IC₅₀ value of 49 µM and N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide with an IC₅₀ value of 4.8 µM .

Cat. No.	Product Name	Chemical Structure

HY-14281S

Trilostane-d3
Trilostane-d₃ is the deuterium-labeled Trilostane (HY-14281). Trilostane-d₃ (Win 24540) is a competitive and orally active 3-β-hydroxysteroiddehydrogenase (3β-HSD) inhibitor. Trilostane-d₃ is a synthetic nonhormonal steroid. Trilostane-d₃ can be used for the research of breast cancer and prostate cancer .

HY-14281S2

Trilostane-d3-1
Trilostane-d₃-1 (Win 24540-d₃-1) is deuterium-labeled Trilostane (HY-14281) .

Host:	Mouse (5)
Reactivity:	Human (5) Mouse (2) Rat (1)
Application:	IHC-P (5) ICC/IF (3) WB (2) FC (2) ELISA (4)
Isotype:	IgG2a (2) IgG2b (1)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (4)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85758

	SGK1 Antibody (YA5450) SGK1	IHC-P, ICC/IF	Human, Rat, Mouse
	SGK1 Antibody (YA5450) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to SGK1.

HY-P84843

	CLEC2 Antibody (YA4540) CLEC2; CLEC2B; PRO1384; QDED721; 1810061I13Rik	IHC-P, FC, ELISA	Human
	CLEC2 Antibody (YA4540) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CLEC2.

HY-P84843A

	CLEC2 Antibody (YA4540)(PBS only) CLEC2; CLEC2B; PRO1384; QDED721; 1810061I13Rik	IHC-P, FC, ELISA	Human
	CLEC2 Antibody (YA4540) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CLEC2.

HY-P85748

	Galectin-3 Antibody (YA5440) LGALS3; MAC2; Galectin-3; Gal-3; 35 kDa lectin; Carbohydrate-binding protein 35; CBP 35; Galactose-specific lectin 3; Galactoside-binding protein; GALBP; IgE-binding protein; L-31; Laminin-binding protein; Lectin L-29; Mac-2 antigen	WB, IHC-P, ICC/IF, ELISA	Human, Mouse
	Galectin-3 Antibody (YA5440) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Galectin-3.

HY-P85848

	CD2 Antibody (YA5540) CD 2; CD2; CD2 antigen; p50; , sheep red blood cell receptor; CD2 antigen; CD2 molecule; CD2_HUMAN; Erythrocyte receptor; FLJ46032; LFA-2; LFA-3 receptor; LFA2; LFA3 receptor; Ly-37; Lymphocyte function antigen 2; lymphocyte-function antigen-2; OTTHUMP00000024366; Rosette receptor; Sheep erythrocyte receptor; SRBC; T cell surface antigen CD2; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T-lymphocyte surface CD2 antigen; T11	IHC-P, WB, ICC/IF, ELISA	Human
	CD2 Antibody (YA5540) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to CD2.

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Cat. No.	Product Name		Classification

HY-RI01168

*hsa-miR-4540* inhibitor**		MicroRNAs miRNA inhibitors
hsa-miR-4540 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R01168

*hsa-miR-4540* mimic**		MicroRNAs miRNA mimics
hsa-miR-4540 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01168A

*hsa-miR-4540* agomir**		MicroRNAs miRNA agomirs
hsa-miR-4540 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01168A

*hsa-miR-4540* antagomir**		MicroRNAs miRNA antagomirs
hsa-miR-4540 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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