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63939

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26

Inhibitors & Agonists

1

Fluorescent Dye

1

Inhibitory Antibodies

7

Antibodies

24

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99634
    Gatipotuzumab

    PankoMab; DS-3939a antibody

    		 Mucin Cancer
    Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC) .
    Gatipotuzumab
  • HY-177442
    DS-3939a

    DS-3939

    		 Antibody-Drug Conjugates (ADCs) Mucin Topoisomerase Apoptosis Cancer
    DS-3939a (DS-3939) is an anti-TA-MUC1 (tumor-associated mucin-1) antibody-drug conjugate (ADC). DS-3939a consists of a humanized anti-TA-MUC1 IgG1 monoclonal antibody Gatipotuzumab ( HY-P99634), a stable and cleavable tetrapeptide-based linker (Gly-Gly-Phe-Gly), and a DNA topoisomerase I inhibitor payload (DXd) (HY-13631D), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E). DS-3939a inhibits the growth of TA-MUC1-positive cancer cells (CFPAC-1, NCI-H2110) by inducing DNA damage and apoptosis. DS-3939a exhibits significant antitumor activity in a variety of TA-MUC1-expressing advanced solid tumors. DS-3939a can be used for the study of TA-MUC1-expressing advanced cancers .
    DS-3939a
  • HY-R03406
    mmu-miR-6399 mimic

    		MicroRNA Cancer
    mmu-miR-6399 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-6399 mimic
    mmu-miR-6399 mimic
  • HY-RI03406
    mmu-miR-6399 inhibitor

    		MicroRNA Cancer
    mmu-miR-6399 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-6399 inhibitor
    mmu-miR-6399 inhibitor
  • HY-R00899
    hsa-miR-3939 mimic

    		MicroRNA Cancer
    hsa-miR-3939 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    hsa-miR-3939 mimic
    hsa-miR-3939 mimic
  • HY-R03400A
    mmu-miR-6393 agomir

    		MicroRNA Cancer
    mmu-miR-6393 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6393 agomir
    mmu-miR-6393 agomir
  • HY-RI03602
    mmu-miR-6939-3p inhibitor

    		MicroRNA Cancer
    mmu-miR-6939-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-6939-3p inhibitor
    mmu-miR-6939-3p inhibitor
  • HY-R03603
    mmu-miR-6939-5p mimic

    		MicroRNA Cancer
    mmu-miR-6939-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-6939-5p mimic
    mmu-miR-6939-5p mimic
  • HY-R03602
    mmu-miR-6939-3p mimic

    		MicroRNA Cancer
    mmu-miR-6939-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-6939-3p mimic
    mmu-miR-6939-3p mimic
  • HY-RI03406A
    mmu-miR-6399 antagomir

    		MicroRNA Cancer
    mmu-miR-6399 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6399 antagomir
    mmu-miR-6399 antagomir
  • HY-RI00899A
    hsa-miR-3939 antagomir

    		MicroRNA Cancer
    hsa-miR-3939 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-3939 antagomir
    hsa-miR-3939 antagomir
  • HY-R00899A
    hsa-miR-3939 agomir

    		MicroRNA Cancer
    hsa-miR-3939 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    hsa-miR-3939 agomir
    hsa-miR-3939 agomir
  • HY-RI03345
    mmu-miR-6339 inhibitor

    		MicroRNA Cancer
    mmu-miR-6339 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-6339 inhibitor
    mmu-miR-6339 inhibitor
  • HY-RI03345A
    mmu-miR-6339 antagomir

    		MicroRNA Cancer
    mmu-miR-6339 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6339 antagomir
    mmu-miR-6339 antagomir
  • HY-R03345A
    mmu-miR-6339 agomir

    		MicroRNA Cancer
    mmu-miR-6339 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6339 agomir
    mmu-miR-6339 agomir
  • HY-RI03400
    mmu-miR-6393 inhibitor

    		MicroRNA Cancer
    mmu-miR-6393 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-6393 inhibitor
    mmu-miR-6393 inhibitor
  • HY-RI00899
    hsa-miR-3939 inhibitor

    		MicroRNA Cancer
    hsa-miR-3939 inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    hsa-miR-3939 inhibitor
    hsa-miR-3939 inhibitor
  • HY-R03400
    mmu-miR-6393 mimic

    		MicroRNA Cancer
    mmu-miR-6393 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-6393 mimic
    mmu-miR-6393 mimic
  • HY-R03406A
    mmu-miR-6399 agomir

    		MicroRNA Cancer
    mmu-miR-6399 agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6399 agomir
    mmu-miR-6399 agomir
  • HY-R03345
    mmu-miR-6339 mimic

    		MicroRNA Cancer
    mmu-miR-6339 mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.
    mmu-miR-6339 mimic
    mmu-miR-6339 mimic
  • HY-RI03400A
    mmu-miR-6393 antagomir

    		MicroRNA Cancer
    mmu-miR-6393 antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6393 antagomir
    mmu-miR-6393 antagomir
  • HY-RI03603A
    mmu-miR-6939-5p antagomir

    		MicroRNA Cancer
    mmu-miR-6939-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6939-5p antagomir
    mmu-miR-6939-5p antagomir
  • HY-R03602A
    mmu-miR-6939-3p agomir

    		MicroRNA Cancer
    mmu-miR-6939-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6939-3p agomir
    mmu-miR-6939-3p agomir
  • HY-RI03603
    mmu-miR-6939-5p inhibitor

    		MicroRNA Cancer
    mmu-miR-6939-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
    mmu-miR-6939-5p inhibitor
    mmu-miR-6939-5p inhibitor
  • HY-R03603A
    mmu-miR-6939-5p agomir

    		MicroRNA Cancer
    mmu-miR-6939-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6939-5p agomir
    mmu-miR-6939-5p agomir
  • HY-RI03602A
    mmu-miR-6939-3p antagomir

    		MicroRNA Cancer
    mmu-miR-6939-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
    mmu-miR-6939-3p antagomir
    mmu-miR-6939-3p antagomir

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