VGLL1 - vestigial like family member 1 Gene

Homo sapiens

Also known as TDU; VGL1

Gene ID: 51442 | Gene type: protein coding

About VGLL1

Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:136,532,215-136,556,799 (from NCBI)

This gene has 4 transcripts (splice variants), 104 orthologues and 2 paralogues. Restricted expression toward placenta (RPKM 103.1).

Summary

The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. [provided by RefSeq, Sep 2009]

VGLL1 Products(1)

mRNA	Protein	Name
NM_016267.4	NP_057351.1	transcription cofactor vestigial-like protein 1

VGLL1 Protein Structure

Vg_Tdu

0
100
200
258 a.a.

Protein Preferred Names

Protein Names

transcription cofactor vestigial-like protein 1

TONDU

Related Diseases

Diseases

Alias

46,Xy Sex Reversal 8

SRXY8	Male Pseudohermaphroditism Due To Deficiency Of Testicular 17,20-Desmolase
Tdd	46,Xy Disorder Of Sex Development Due To Testicular 17,20-Desmolase Deficiency
46xy Sex Reversal 8	46xy Sex Reversal 8, Modifier Of
Male Pseudohermaphroditism: Deficiency Of Testicular 17,20-Desmolase

Sveinsson Chorioretinal Atrophy

SCRA	Atrophia Areata
Helicoid Peripapillary Chorioretinal Degeneration	Hpcd
Aa	Peripapillary Chorioretinal Degeneration, Icelandic Type
Helicoidal Peripapillary Chorioretinal Degeneration	Atrophy, Chorioretinal, Sveinsson

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15644	VGLL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	VGLL1	VGNC	VGNC:56958
Felis catus	VGLL1	VGNC	VGNC:82514
Mus musculus	VGLL1	MGD	MGI:2655768
Canis familiaris	VGLL1	VGNC	VGNC:48257
Rattus norvegicus	VGLL1	RGD	RGD:1564038

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