2. Gene
  3. HASPIN - histone H3 associated protein kinase Gene

HASPIN - histone H3 associated protein kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as GSG2

Gene ID: 83903 | Gene type: protein coding

About HASPIN

Cytogenetic location: 17p13.2 Genomic coordinates (GRCh38): 17:3,723,903-3,726,699 (from NCBI)

This gene has 1 transcript (splice variant), 174 orthologues and 4 paralogues.

Summary

Enables ATP binding activity and histone kinase activity (H3-T3 specific). Involved in histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore; intracellular signal transduction; and mitotic sister chromatid cohesion. Located in centrosome; nucleoplasm; and spindle. [provided by Alliance of Genome Resources, Apr 2022]

HASPIN Products(1)

mRNA Protein Name
NM_031965.2 NP_114171.2 serine/threonine-protein kinase haspin

HASPIN Protein Structure

Pkinase

Pkinase: Protein kinase domain (486 - 687)

Haspin_kinase

Haspin_kinase: Haspin like kinase domain (708 - 797)

  • 0
  • 200
  • 400
  • 600
  • 798 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase haspin

H-haspin

germ cell associated 2, haspin

germ cell-specific gene 2 protein

haploid germ cell-specific nuclear protein kinase

Related Agents

Pre-clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15424 5-Iodotubercidin Inhibitor 99.64% Unkown
HY-15217 CHR-6494 Inhibitor 98.07% Unkown
HY-13455 LDN-192960 Inhibitor 99.56% Unkown
HY-110320 LDN-209929 dihydrochloride Inhibitor ≥99.0% Unkown
HY-13455A LDN-192960 hydrochloride Inhibitor 99.78% Unkown
HY-146636 Haspin-IN-3 Inhibitor 98.14% Unkown
HY-110350 CHR-6494 TFA Inhibitor / Unkown
HY-146586 Haspin-IN-1 Inhibitor / Unkown
HY-146587 Haspin-IN-2 Inhibitor / Unkown
HY-155341 HSK205 Inhibitor / Unkown
HY-RS06009 HASPIN Human Pre-designed siRNA Set A / Unkown
HY-RS06010 Haspin Mouse Pre-designed siRNA Set A / Unkown
HY-RS06011 Haspin Rat Pre-designed siRNA Set A / Unkown
HY-100368 MELK-8a / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus HASPIN MGD MGI:1194498
Bos taurus HASPIN VGNC VGNC:55834
Macaca mulatta HASPIN VGNC VGNC:104614
Canis familiaris HASPIN VGNC VGNC:49092
Felis catus HASPIN VGNC VGNC:62754
Rattus norvegicus HASPIN RGD RGD:1596276