SPMIP6 - sperm microtubule inner protein 6 Gene

Also Known as CBE1; SMRP1; C9orf24; NYD-SP22; bA573M23.4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84688

Summary

This gene encodes a nuclear- or perinuclear-localized protein with no predicted domains or similarity to other known proteins. Expression of this gene is induced during the differentiation of bronchial epithelial cells, and the encoded protein may play a role in ciliogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Broad expression in brain (RPKM 5.2), testis (RPKM 5.0) and 21 other tissues.

SPMIP6 Products (5)

mRNA Protein Name
NM_001252195.2 NP_001239124.1 sperm microtubule inner protein 6 isoform 4
NM_001410962.1 NP_001397891.1 sperm microtubule inner protein 6 isoform 5
NM_032596.4 NP_115985.2 sperm microtubule inner protein 6 isoform 1
NM_147168.2 NP_671697.1 sperm microtubule inner protein 6 isoform 2
NM_147169.3 NP_671698.1 sperm microtubule inner protein 6 isoform 3

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
Cellular Component GO Annotation Evidence Références Source
located in nucleus IDA
IDA: Inferred from direct assay
15242845 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
15242845 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SPMIP6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
SPMIP6 Q8NCR6 KRTAP9-3 Homo sapiens Q9BYQ3
Validated Y2H
32296183
Intra
SPMIP6 Q8NCR6 KRTAP19-5 Homo sapiens Q3LI72
Y2H Prey Pooling
32296183
Intra
SPMIP6 Q8NCR6 KRTAP19-5 Homo sapiens Q3LI72
Y2H Array
32296183
Intra
SPMIP6 Q8NCR6 CABP2 Homo sapiens Q9NPB3
Validated Y2H
32296183
Intra
SPMIP6 Q8NCR6 KRTAP19-6 Homo sapiens Q3LI70
Y2H Prey Pooling
32296183
Intra
SPMIP6 Q8NCR6 KRTAP19-6 Homo sapiens Q3LI70
Y2H Array
32296183
Intra
SPMIP6 Q8NCR6 A1CF Homo sapiens Q9NQ94
Validated Y2H
32296183
Intra
SPMIP6 Q8NCR6 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
SPMIP6 Q8NCR6 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
SPMIP6 Q8NCR6 TSSK3 Homo sapiens Q96PN8
Validated Y2H
32296183
Intra
SPMIP6 Q8NCR6 SPG21 Homo sapiens Q9NZD8
Validated Y2H
32296183
Intra
SPMIP6 Q8NCR6 CATSPER1 Homo sapiens Q8NEC5
Validated Y2H
32296183
Intra
SPMIP6 Q8NCR6 TEKT4 Homo sapiens Q8WW24
Validated Y2H
32296183
Intra
SPMIP6 Q8NCR6 PIK3R3 Homo sapiens Q92569
Validated Y2H
32296183
Intra
SPMIP6 Q8NCR6 AIRIM Homo sapiens Q9NX04
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction