RAB36 - RAB36, member RAS oncogene family Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9609

About RAB36

Cytogenetic location: 22q11.23 Genomic coordinates (GRCh38): 22:23,145,324-23,169,280 (from NCBI)

This gene has 3 transcripts (splice variants), 175 orthologues and 68 paralogues. Broad expression in thyroid (RPKM 6.1), kidney (RPKM 2.1) and 17 other tissues.

Summary

Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in protein transport. Predicted to be located in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]

RAB36 Products (3)

mRNA Protein Name
NM_001349877.1 NP_001336806.1 ras-related protein Rab-36 isoform 1
NM_001349878.1 NP_001336807.1 ras-related protein Rab-36 isoform 2
NM_004914.5 NP_004905.3 ras-related protein Rab-36 isoform 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RAB36 Protein Structure

Ras

Ras: Ras family (125 - 285)

  • 0
  • 100
  • 200
  • 300
  • 333 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-36

  • small GTP-binding protein Rab36

RAB36 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RAB36 O95755 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
RAB36 O95755 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Ulna And Fibula, Absence Of, With Severe Limb Deficiency

  • Schinzel Phocomelia Syndrome

  • Aarrs

  • Limb/Pelvis-Hypoplasia/Aplasia Syndrome

  • LPHAS

  • Schinzel Type Phocomelia

  • Absence Of Ulna And Fibula With Severe Limb Deficiency

  • Al-Awadi/Raas-Rothschild Syndrome

  • Al Awadi-Raas-Rothschild Syndrome

  • Al-Awadi/Raas-Rothschild/Schinzel Phocomelia Syndrome

  • Aplasia/Hypoplasia Of Limbs And Pelvis

  • Congenital Absence Of Ulna And Fibula

  • Severe Limb Deficit

  • Phocomelia, Schinzel Type

  • Al-Awadi-Raas-Rothschild Syndrome

  • Ulna And Fibula Absence Of With Severe Limb Deficiency

  • Limb Pelvis Hypoplasia Aplasia Syndrome

  • Limb/Pelvis/Uterus-Hypoplasia/Aplasia Syndrome

  • Ulna And Fibula, Absence Of, With Sever Limb Deficiency
Thrombocytopenia-Absent Radius Syndrome

  • Tar Syndrome

  • Radial Aplasia-Thrombocytopenia Syndrome

  • Absent Radii And Thrombocytopenia

  • TAR

  • Chromosome 1q21.1 Deletion Syndrome, 200-Kb

  • Thrombocytopenia Absent Radius Syndrome

  • Thrombocytopenia Absent Radii

  • Chromosome 1q21.1 Deletion Syndrome

  • Thrombocytopenia With Absent Radii Syndrome

  • Radial Aplasia-Amegakaryocytic Thrombocytopenia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11550 RAB36 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus RAB36 VGNC VGNC:80474
Bos taurus RAB36 VGNC VGNC:59360
Canis familiaris RAB36 VGNC VGNC:49953
Mus musculus RAB36 MGD MGI:1924127
Rattus norvegicus RAB36 RGD RGD:1596098
Macaca mulatta RAB36 VGNC VGNC:81534
Others RAB36 NCBI