ELOA2 - elongin A2 Gene

Also Known as HsT832; TCEB3B; TCEB3L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51224

Summary

This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis. [provided by RefSeq, Jul 2008]

ELOA2 Products (1)

mRNA Protein Name
NG_050760.1 [RefSeqGene]

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ELOA2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ELOA2 Q8IYF1 SREK1IP1 Homo sapiens Q8N9Q2
Validated Y2H
32296183
Intra
ELOA2 Q8IYF1 ZCCHC10 Homo sapiens Q8TBK6
Validated Y2H
25416956
Intra
ELOA2 Q8IYF1 ZCCHC10 Homo sapiens Q8TBK6
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04317 ELOA Human Pre-designed siRNA Set A Pre-designed Set / Unkown