BAX - BCL2 associated X, apoptosis regulator Gene

Also Known as BCL2L4

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 581

About BAX

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:48,954,875-48,961,798 (from NCBI)

This gene has 12 transcripts (splice variants), 206 orthologues, 8 paralogues and is associated with 51 phenotypes. Ubiquitous expression in colon (RPKM 24.0), spleen (RPKM 21.8) and 25 other tissues.

Summary

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of Bax to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated Apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Dec 2019]

BAX Products (11)

mRNA	Protein	Name
NM_138762.2
NM_138761.4	NP_620116.1	apoptosis regulator BAX isoform alpha
NR_027882.2
NM_001291428.2	NP_001278357.1	apoptosis regulator BAX isoform 1
NM_001291431.2	NP_001278360.1	apoptosis regulator BAX isoform zeta
NM_001291429.2	NP_001278358.1	apoptosis regulator BAX isoform gamma
NM_004324.4	NP_004315.1	apoptosis regulator BAX isoform beta
NM_138763.4	NP_620118.1	apoptosis regulator BAX isoform delta
NM_001291430.2	NP_001278359.1	apoptosis regulator BAX isoform lambda
XM_047439168.1	XP_047295124.1	apoptosis regulator BAX isoform X1
NM_138764.5	NP_620119.2	apoptosis regulator BAX isoform sigma

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables BH3 domain binding	IDA IDA: Inferred from direct assay	21199865	GOA
enables BH3 domain binding	IPI IPI: Inferred from physical interaction	15705586	GOA
enables channel activity	IDA IDA: Inferred from direct assay	9219694	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	10620504	GOA
enables lipid binding	IDA IDA: Inferred from direct assay	14522999	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	9027312	GOA
enables protein heterodimerization activity	IPI IPI: Inferred from physical interaction	9111042	GOA
enables protein homodimerization activity	IDA IDA: Inferred from direct assay	16608847	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in B cell apoptotic process	IDA IDA: Inferred from direct assay	15214043	GOA
involved in B cell receptor apoptotic signaling pathway	IDA IDA: Inferred from direct assay	15214043	GOA
involved in apoptotic mitochondrial changes	IDA IDA: Inferred from direct assay	9843949	GOA
involved in apoptotic process	IDA IDA: Inferred from direct assay	9660918	GOA
involved in apoptotic process	IMP IMP: Inferred from mutant phenotype	9531611	GOA
involved in apoptotic signaling pathway	IDA IDA: Inferred from direct assay	16424160	GOA
involved in cellular response to virus	IDA IDA: Inferred from direct assay	25609812	GOA
involved in establishment or maintenance of transmembrane electrochemical gradient	IDA IDA: Inferred from direct assay	9843949	GOA
involved in execution phase of apoptosis	IMP IMP: Inferred from mutant phenotype	11350920	GOA
involved in extrinsic apoptotic signaling pathway	IDA IDA: Inferred from direct assay	15214043	GOA
involved in intrinsic apoptotic signaling pathway	IDA IDA: Inferred from direct assay	9219694	GOA
involved in intrinsic apoptotic signaling pathway in response to DNA damage	IDA IDA: Inferred from direct assay	11912183	GOA
involved in mitochondrial fragmentation involved in apoptotic process	IDA IDA: Inferred from direct assay	12499352	GOA
involved in mitochondrial fusion	IDA IDA: Inferred from direct assay	14769861	GOA
involved in negative regulation of mitochondrial membrane potential	IDA IDA: Inferred from direct assay	16751333	GOA
involved in negative regulation of protein binding	IDA IDA: Inferred from direct assay	9388232	GOA
involved in positive regulation of apoptotic DNA fragmentation	IMP IMP: Inferred from mutant phenotype	11350920	GOA
involved in positive regulation of apoptotic process	IDA IDA: Inferred from direct assay	16751333	GOA
involved in positive regulation of apoptotic process	IMP IMP: Inferred from mutant phenotype	17289999	GOA
involved in positive regulation of intrinsic apoptotic signaling pathway	IMP IMP: Inferred from mutant phenotype	14963330	GOA
involved in positive regulation of neuron apoptotic process	IDA IDA: Inferred from direct assay	15637643	GOA
involved in positive regulation of protein-containing complex assembly	IDA IDA: Inferred from direct assay	9111042	GOA
involved in positive regulation of release of cytochrome c from mitochondria	IDA IDA: Inferred from direct assay	14963330	GOA
involved in positive regulation of release of cytochrome c from mitochondria	IMP IMP: Inferred from mutant phenotype	21262771	GOA
involved in regulation of apoptotic process	IDA IDA: Inferred from direct assay	25609812	GOA
involved in regulation of mitochondrial membrane potential	IDA IDA: Inferred from direct assay	9843949	GOA
involved in release of cytochrome c from mitochondria	IDA IDA: Inferred from direct assay	9843949	GOA
involved in release of matrix enzymes from mitochondria	IDA IDA: Inferred from direct assay	9843949	GOA
involved in response to toxic substance	IDA IDA: Inferred from direct assay	16307838	GOA
involved in supramolecular fiber organization	IDA IDA: Inferred from direct assay	31690630	GOA

Cellular Component GO Annotation	Evidence	References	Source
part of BAK complex	IDA IDA: Inferred from direct assay	16113678	GOA
part of BAX complex	IDA IDA: Inferred from direct assay	14522999	GOA
part of Bcl-2 family protein complex	IDA IDA: Inferred from direct assay	21199865	GOA
colocalizes with cell periphery	IDA IDA: Inferred from direct assay	21803450	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	16302269	GOA
located in cytosol	IDA IDA: Inferred from direct assay	11912183	GOA
located in endoplasmic reticulum	IDA IDA: Inferred from direct assay	16424160	GOA
located in endoplasmic reticulum membrane	IDA IDA: Inferred from direct assay	16424160	GOA
located in mitochondrial outer membrane	IDA IDA: Inferred from direct assay	29531808	GOA
part of mitochondrial permeability transition pore complex	IDA IDA: Inferred from direct assay	9843949	GOA
located in mitochondrion	IDA IDA: Inferred from direct assay	11912183	GOA
located in nuclear envelope	IDA IDA: Inferred from direct assay	12925958	GOA
located in nucleus	IDA IDA: Inferred from direct assay	12925958	GOA
located in nucleus	IMP IMP: Inferred from mutant phenotype	15102863	GOA
part of pore complex	IDA IDA: Inferred from direct assay	9219694	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BAX Protein Structure

Bcl-2

0
100
192 a.a.

Protein Preferred Names	Protein Names
apoptosis regulator BAX	BCL2 associated X protein BCL2-associated X protein omega Baxdelta2G9 Baxdelta2G9omega Baxdelta2omega bcl-2-like protein 4 bcl2-L-4

BAX Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	BAX	Q07812	MCL1	Homo sapiens	Q07820	Anti Bait CoIP	17525735
Intra	BAX	Q07812	MCL1	Homo sapiens	Q07820	Anti Tag CoIP	18981409
Intra	BAX	Q07812	MCL1	Homo sapiens	Q07820	Anti Tag CoIP	21199865
Cross	BAX	Q07812	TOM22	Saccharomyces cerevisiae	P49334	Anti Bait CoIP	22198199
Cross	BAX	Q07812	TOM40	Saccharomyces cerevisiae	P23644	Anti Bait CoIP	22198199
Cross	BAX	Q07812	TOM70	Saccharomyces cerevisiae	P07213	Anti Bait CoIP	22198199
Cross	BAX	Q07812	P70444-PRO_0000223236	Mus musculus	P70444-PRO_0000223236	FRET	19062087
Intra	BAX	Q07812	RNF144B	Homo sapiens	Q7Z419	Anti Bait CoIP	20300062
Intra	BAX	Q07812	RNF144B	Homo sapiens	Q7Z419	BN-PAGE	20300062
Intra	BAX	Q07812	BCL2L1	Homo sapiens	Q07817-1	Anti Tag CoIP	17289999
Intra	BAX	Q07812	BCL2L1	Homo sapiens	Q07817-1	Anti Bait CoIP	15131699
Intra	BAX	Q07812	BCL2L1	Homo sapiens	Q07817-1	X-Ray Diffraction	21199865
Intra	BAX	Q07812	BCL2L1	Homo sapiens	Q07817-1	FPS	19074440
Intra	BAX	Q07812	BCL2L1	Homo sapiens	Q07817-1	Fluorescence	21458670
Intra	BAX	Q07812	BCL2L1	Homo sapiens	Q07817-1	Anti Bait CoIP	21671007
Intra	BAX	Q07812	BCL2L1	Homo sapiens	Q07817-1	Anti Tag CoIP	18981409
Intra	BAX	Q07812	BCL2L1	Homo sapiens	Q07817-1	Anti Tag CoIP	21199865
Intra	BAX	Q07812	UVRAG	Homo sapiens	Q9P2Y5	Anti Bait CoIP	21597469
Intra	BAX	Q07812	UVRAG	Homo sapiens	Q9P2Y5	Pull Down	21597469
Intra	BAX	Q07812	XRCC6	Homo sapiens	P12956	Anti Bait CoIP	15205477
Intra	BAX	Q07812	BCL2L12	Homo sapiens	Q9HB09	Y2H	29749471
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	GMS	19062087
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Anti Tag CoIP	17289999
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Crosslink	23374347
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Crosslink	17668322
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	BN-PAGE	22198199
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Crosslink	19767770
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Crosslink	18835031
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Crosslink	19074440
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	GMS	10620504
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	BN-PAGE	23374347
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Crosslink	18547146
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Crosslink	20850011
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Polymerization	20850011
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Anti Bait CoIP	19767770
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Comigration in SDS	14963330
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	Experimental Interac	1558161
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	FRET	19062087
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	X-Ray Diffraction	23374347
Intra	BAX	Q07812	BAX	Homo sapiens	Q07812	GMS	20360684
Intra	BAX	Q07812	BID	Homo sapiens	P55957	PLA	25241761
Intra	BAX	Q07812	BID	Homo sapiens	P55957	SPR	17289999
Intra	BAX	Q07812	BID	Homo sapiens	P55957	Anti Bait CoIP	20956295
Intra	BAX	Q07812	BAK1	Homo sapiens	Q16611	Anti Tag CoIP	17289999
Intra	BAX	Q07812	BAK1	Homo sapiens	Q16611	Anti Tag CoIP	15901672
Intra	BAX	Q07812	BAK1	Homo sapiens	Q16611	CoIP	16439990
Intra	BAX	Q07812	BCL2L11	Homo sapiens	O43521	Anti Bait CoIP	17525735
Intra	BAX	Q07812	BCL2L11	Homo sapiens	O43521	FRET	19427863
Intra	BAX	Q07812	BCL2L11	Homo sapiens	O43521	SPR	17289999
Intra	BAX	Q07812	BCL2L11	Homo sapiens	O43521	Anti Bait CoIP	19427863
Intra	BAX	Q07812	SH3GLB1	Homo sapiens	Q9Y371-1	Anti Bait CoIP	19074440
Intra	BAX	Q07812	BCL2L2	Homo sapiens	Q92843	Anti Tag CoIP	17289999
Intra	BAX	Q07812	BCL2L2	Homo sapiens	Q92843	Anti Tag CoIP	18981409
Cross	BAX	Q07812	OPG035	vaccinia virus	P17361	Anti Tag CoIP	17485524
Cross	BAX	Q07812	OPG035	vaccinia virus	P17361	Anti Bait CoIP	17485524
Intra	BAX	Q07812	HSF2BP	Homo sapiens	O75031	Y2H Prey Pooling	32296183
Intra	BAX	Q07812	HSF2BP	Homo sapiens	O75031	Y2H Array	32296183
Intra	BAX	Q07812	PYCARD	Homo sapiens	Q9ULZ3	Anti Bait CoIP	14730312
Intra	BAX	Q07812	PYCARD	Homo sapiens	Q9ULZ3	Pull Down	14730312
Intra	BAX	Q07812	PYCARD	Homo sapiens	Q9ULZ3	Confocal	14730312
Intra	BAX	Q07812	PYCARD	Homo sapiens	Q9ULZ3	Anti Tag CoIP	14730312
Intra	BAX	Q07812	BCL2	Homo sapiens	P10415	Anti Tag CoIP	21199865
Intra	BAX	Q07812	BCL2	Homo sapiens	P10415	Anti Tag CoIP	17289999
Intra	BAX	Q07812	BCL2	Homo sapiens	P10415	Anti Bait CoIP	17525735
Intra	BAX	Q07812	BCL2	Homo sapiens	P10415	IF	26004684
Intra	BAX	Q07812	BCL2	Homo sapiens	P10415	Anti Tag CoIP	18981409
Intra	BAX	Q07812	KCNA3	Homo sapiens	P22001	Anti Bait CoIP	18818304
Intra	BAX	Q07812	MT-RNR2	Homo sapiens	Q8IVG9	FPS	12732850
Intra	BAX	Q07812	MT-RNR2	Homo sapiens	Q8IVG9	Y2H	12732850
Intra	BAX	Q07812	SNCA	Homo sapiens	P37840	PLA	25241761
Cross	BAX	Q07812	UL37	Human cytomegalovirus	P16778	Fluorescence Spectr	23213219
Cross	BAX	Q07812	UL37	Human cytomegalovirus	P16778	NMR	23213219
Cross	BAX	Q07812	tom40	Neurospora crassa	P24391	Anti Bait CoIP	17635912
Cross	BAX	Q07812	P26662-PRO_0000037647	Hepatitis C virus	P26662-PRO_0000037647	Anti Bait CoIP	12925958
Cross	BAX	Q07812	P26662-PRO_0000037647	Hepatitis C virus	P26662-PRO_0000037647	Pull Down	12925958

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant BAX Proteins

Cat. No.	Product Name	Accession	Purity
HY-P7651	Bax Protein, Human (His)	Q07812-1 (M1-Q171)	≥ 95%, as determined by reducing SDS-PAGE.

BAX Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80027	Bax Antibody (YA825)	WB, IHC-P	Human, Mouse, Rat
HY-P80028	Bax Antibody (YA591)	WB, ICC/IF, IP, FC	Human, Mouse, Rat
HY-P80564	Bax Antibody (YA826)	WB	Human, Monkey
HY-P80564A	Bax Antibody (YA826)(PBS only)	WB	Human, Monkey
HY-P84506	Bax Antibody (YA4203)	WB, IHC-P, FC, ELISA	Human, Mouse, Rat, Rabbit, Monkey
HY-P84506A	Bax Antibody (YA4203)(PBS only)	WB, IHC-P, FC, ELISA	Human, Mouse, Rat, Rabbit, Monkey
HY-P86515	Bax Antibody (YA6207)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Colon Adenocarcinoma	Adenocarcinoma Of Colon Adenocarcinoma Of The Colon Colonic Adenocarcinoma
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Ataxia-Telangiectasia	Ataxia Telangiectasia Louis-Bar Syndrome AT At1 Ataxia-Telangiectasia Syndrome Ataxia - Telangiectasia Variant Boder-Sedgwick Syndrome Louis Bar Syndrome Cerebello-Oculocutaneous Telangiectasia Immunodeficiency With Ataxia Telangiectasia A-T Ataxia Telangiectasia Syndrome Atm Telangiectasia, Cerebello-Oculocutaneous Ataxia-Telangiectasia Variant
Neuroblastoma	Nb Neuroblastoma, Susceptibility To Neuroblastomas Central Neuroblastoma
Parkinson Disease, Late-Onset	Parkinson Disease Parkinson'S Disease PD PARK Parkinson Disease, Susceptibility To Late Onset Parkinson'S Disease Late Onset Parkinson Disease Paralysis Agitans Primary Parkinsonism Idiopathic Parkinson Disease Parkinson'S Parkinson Disease, Late-Onset, Susceptibility To Parkinson Disease, Age Of Onset, Modifier Lewy Body Parkinson Disease Idiopathic Parkinson'S Disease Pd - [Parkinson Disease] Parkinson Disease Nos Parkinson, Nos Primary Parkinson Disease
Gastric Cancer	Stomach Cancer Stomach Carcinoma Gastric Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Torticollis	Contracture Of Neck Wry Neck Wry Neck/Torticollis
Follicular Lymphoma	Lymphoma, Follicular Lymphoma Follicular Brill-Symmers' Disease Large Cell Follicular Non-Hodgkin Lymphoma Diffuse Follicle Centre Lymphoma Diffuse Follicular Lymphoma Nos Follicular Nodular Non-Hodgkin Lymphoma, Unspecified Follicular Large Cell Cleaved Or Noncleaved Lymphoma Large Cell Follicular Noncleaved Lymphoma Follicular Lymphoma With Or Without Diffuse Areas Histiocytic Follicular Lymphoma Histiocytic Nodular Lymphoma Histiocytic Nodular Malignant Lymphoma Large Cell Follicular Lymphoma Large Cell Noncleaved Follicular Lymphoma Large Cell Noncleaved Follicular Malignant Lymphoma Nodular Reticulum Cell Sarcoma Noncleaved Follicular Lymphoma
T-Cell Acute Lymphoblastic Leukemia	T-Cell Leukemia Acute T Cell Leukemia Precursor T Lymphoblastic Leukemia Precursor T-Lymphoblastic Lymphoma/Leukemia T Acute Lymphoblastic Leukemia T-Cell Acute Lymphocytic Leukaemia T-Cell Lymphoblastic Leukemia/Lymphoma Leukemia T-Cell Leukemia, T-Cell Leukemia, Acute, Lymphoblastic, T-Cell Leukemia, T-Cell Acute Lymphoblastic Leukemia, Acute T-Cell Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Precursor T-Cell Lymphoblastic Lymphoma Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma
Brain Cancer	Malignant Neoplasm Of Brain Adult Brain Tumor Brain Neoplasms Brain Neoplasm Neoplasm Of Brain Primary Malignant Neoplasm Of Brain Brain Tumors Adult Malignant Brain Neoplasm Brain Neoplasm, Adult Bt - Brain Tumour Malignant Brain Tumour Malignant Primary Brain Neoplasm Malignant Primary Brain Tumor Malignant Tumor Of Adult Brain Malignant Tumor Of Brain Primary Brain Neoplasm Primary Brain Tumor Tumor Of The Brain Brain Tumor, Adult Brain Tumor Primary Malignant Primary Brain Tumors Primary Brain Tumors Cancer, Brain Brain Tumor, Primary
Osteogenic Sarcoma	Osteosarcoma OSRC Osteosarcoma, Somatic Neoplasms, Bone Tissue Bone Tissue Neoplasm Osteoid Sarcoma Skeletal Sarcoma Osteosarcoma Of Bone Bone Sarcoma
Cervical Adenoid Cystic Carcinoma	Adenoid Cystic Carcinoma Of The Cervix Uteri
Pancreatic Cancer	Pancreatic Carcinoma Familial Pancreatic Carcinoma Pancreatic Neoplasm Carcinoma Of Pancreas Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Cancer Of The Pancreas Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
B-Cell Lymphoma	Lymphoma, B-Cell B-Cell Lymphomas B-Cell Lymphocytic Neoplasm Lymphoma B-Cell B-Cell Lymphoma Nos
Lung Cancer Susceptibility 3	Lung Adenocarcinoma Adenocarcinoma Of Lung LNCR3 Adenocarcinoma Of Lung, Susceptibility To Bronchogenic Lung Adenocarcinoma Nonsmall Cell Adenocarcinoma Adenocarcinoma Lung Lung Adenocarcinomas Non-Small Cell Adenocarcinoma
Denys-Drash Syndrome	Drash Syndrome DDS Nephropathy, Wilms Tumor, And Genital Anomalies Wilms Tumor And Pseudohermaphroditism Wilms Tumor And Pseudo- Or True Hermaphroditism Nephropathy Associated With Male Pseudohermaphroditism And Wilms' Tumor Pseudohermaphroditism, Nephron Disorder And Wilms' Tumor Wilms Tumor-Dsd Syndrome Wilms Tumor-Disorder Of Sex Development Syndrome
Liver Disease	Liver Failure Liver Diseases Abnormality Of The Liver Liver Dysfunction Disorder Of Liver Hepatic Disorder Hepatic Disease Disease Of Bilirubin Metabolism Disorder Of Bilirubin Metabolism Liver Decompensation Liver Function Failure Hepatic Failure Nos Liver Failure Nos End Stage Liver Disease Decompensated Liver Failure Decompensation Of Liver Function Hepatic Decompensation Hepatic Insufficiency Liver Cell Necrosis With Hepatic Failure Liver Insufficiency Decompensated Liver Disease End Stage Liver Failure Liver Necrosis With Hepatic Failure
Li-Fraumeni Syndrome	Sarcoma Family Syndrome Of Li And Fraumeni Sbla Syndrome LFS Li-Fraumeni Familiar Cancer Susceptibility Syndrome Sarcoma, Breast, Leukaemia And Adrenal Gland Syndrome Lfs1 Li Fraumeni Syndrome Sarcoma, Breast, Leukemia, And Adrenal Gland Syndrome Lfl Sbla Syndrome Li-Fraumeni-Like Syndrome Li-Fraumeni Syndrome 1
Lymphoma	Lymphoid Cancer Lymphomas Lymphoid Cancers Lymphoid Neoplasm Lymphoma Nos Nhl - [Non-Hodgkin Lymphoma] Non-Hodgkin Lymphoma Non-Hodgkin Lymphoma, Nos Non-Hodgkin Malignant Lymphoma Nos
Lymphoma, Non-Hodgkin, Familial	Non-Hodgkin Lymphoma Lymphoma, Non-Hodgkin NHL Lymphoma, Non-Hodgkin, Somatic Lymphoma, Follicular, Somatic Familial Non-Hodgkin Lymphoma Lymphoma Non-Hodgkins Follicular Lymphoma, Somatic Lymphosarcoma Non-Hodgkins Lymphoma
Myeloma, Multiple	Multiple Myeloma Kahler Disease Myelomatosis Plasma Cell Myeloma Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler'S Disease Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Glioblastoma	Glioblastoma Multiforme Gbm Adult Glioblastoma Multiforme Grade Iv Adult Astrocytic Tumor Primary Glioblastoma Multiforme Spongioblastoma Multiforme Adult Glioblastoma Primary Glioblastoma
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Protection Against Lung Cancer, Susceptibility To Adenocarcinoma Of Lung, Somatic Nonsmall Cell Lung Cancer Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Panniculitis	Nodular Panniculitis
Scrapie
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Breast Adenocarcinoma	Mammary Adenocarcinoma Adenocarcinoma Of Breast
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Ovary Adenocarcinoma	Ovarian Adenocarcinoma Adenocarcinoma Of The Ovary Ovarian Adenoacanthoma Adenocarcinoma Of Ovary
High Grade Glioma	Malignant Glioma Glial Cell Tumor Glioma, Malignant Malignant Neuroglial Tumor Neuroglial Tumor Glioma Malignant Gliomas
Fuchs' Endothelial Dystrophy	Fuchs Endothelial Corneal Dystrophy Fuchs Endothelial Dystrophy Fuchs Dystrophy Fced Fuchs' Corneal Dystrophy Fuchs' Endothelial Corneal Dystrophy Fuchs Atrophy Fuchs Corneal Dystrophy Endoepithelial Corneal Dystrophy Fecd Late Hereditary Endothelial Dystrophy Corneal Dystrophy, Fuchs Endothelial Dystrophy, Corneal, Fuchs Endothelial Corneal Dystrophy, Fuchs' Endothelial, 1
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Glycogen Storage Disease	Glycogenosis Glycogenoses Gsd Storage Disease, Glycogen Gsd - [Glycogen Storage Disease] Glycogen Thesaurismosis Diffuse Glycogenosis Generalised Glycogen Storage Disease Generalised Glycogenosis Generalised Glycogen Storage Disease Of Infants Glycogen Synthase Deficiency
Absolute Glaucoma	Blind Hypertensive Eye Glaucoma Absolute
Adenocarcinoma	Adenocarcinomas Adenoacanthoma Of Unspecified Site Adenocarcinoid Of Unspecified Site Adenocarcinoid Tumour Of Unspecified Site Adenocarcinoma And Carcinoid Combined Of Unspecified Site Adenocarcinoma Nos
Melanoma	Malignant Melanoma Cutaneous Melanoma Naevocarcinoma Malignant Melanomas
Oral Lichen Planus	Oral Lichenoid Lesions Lichen Planus Oral Lichen Planus, Oral
Laryngeal Squamous Cell Carcinoma	Epidermoid Carcinoma Of The Larynx Squamous Cell Carcinoma Of Larynx Squamous Cell Carcinoma Of The Larynx Squamous Cell Carcinoma Of Head And Neck
Leukemia	Leukemias Leukaemia, Unspecified, Without Mention Of Remission Aleukemic Leukaemia Chronic Leukaemia Subacute Leukaemia Leukaemia Disorder Leukaemia Nos
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Ischemia	Acute Coronary Syndrome
Bladder Cancer	Urinary Bladder Cancer Bladder Carcinoma Urinary Bladder Carcinoma Bladder Neoplasm Bladder Tumor Cancer, Bladder Malignant Neoplasm Of Urinary Bladder Carcinoma Of Bladder Bladder Cancer, Somatic Tumor Of The Bladder Carcinoma Of Urinary Bladder Bladder Carcinoma Urinary Cancer Of The Urinary Bladder Cancer, Urinary Bladder Malignant Bladder Neoplasm Malignant Bladder Tumor Neoplasm Of The Bladder Neoplasm Of The Urinary Bladder Tumor Of The Urinary Bladder Urinary Bladder Neoplasm BLC Urothelial Carcinoma Of The Bladder Bladder Tumors Urinary Bladder Neoplasms Bladder Cancer Nos Vesical Cancer Nos Malignant Neoplasm Of Bladder, Part Unspecified Malignant Tumour Of Urinary Bladder Primary Malignant Neoplasm Of Bladder
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Nasopharyngeal Carcinoma	Malignant Neoplasm Of Nasopharynx Npc Nasopharyngeal Cancer Nasopharyngeal Carcinoma 1 Nasopharynx Carcinoma Nasopharyngeal Neoplasms Npca Carcinoma Of Nasopharynx Malignant Nasopharyngeal Tumor Nasopharynx Cancer Squamous Cell Carcinoma Of The Nasopharynx Nasopharyngeal Neoplasm Cancer Of Nasopharynx
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Cancer Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Acute Promyelocytic Leukemia	Leukemia, Acute Promyelocytic Acute Myeloblastic Leukemia Type 3 Aml M3 APL Leukemia, Acute Promyelocytic, Somatic Aml With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Apml Acute Myeloblastic Leukemia 3 Acute Myeloid Leukemia With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Acute Myeloblastic Leukaemia Type 3 Acute Myeloid Leukaemia M3 Acute Myeloid Leukemia M3 Acute Promyelocytic Leukaemia M3 Anll Myeloid Leukemia, Acute, M3 Leukemia Promyelocytic Acute Leukemia, Promyelocytic, Acute Leukemia, Acute, Promyelocytic
Basal Cell Carcinoma	Basal Cell Cancer Basal Cell Neoplasm Basal Cell Carcinoma Of Skin Malignant Basal Cell Tumor Basal Cell Tumor Epithelioma Basal Cell Malignant Basal Cell Neoplasm Rodent Ulcer Carcinoma Basal Cell Neoplasms, Basal Cell Basal Cell Carcinomas Experimental Organism Basal Cell Carcinoma Nodulo-Ulcerative Basal Cell Carcinoma Basalioma Basal Cell Epithelioma Of Skin Bcc - [Basal Cell Carcinoma] Of Skin Rodent Ulcer Of Skin Rodent Ulcer Of Unspecified Site Basal Cell Epithelioma Of Unspecified Site

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B1192	Estradiol benzoate		99.90%	Unkown
HY-B1357	Digitoxin		99.22%	Yes
HY-B0402	Amantadine	Modulator	99.90%	Unkown
HY-B0402A	Amantadine hydrochloride	Modulator	98.0%	Yes
HY-B0621	Triclabendazole		99.36%	Yes
HY-B0402B	Amantadine sulfate	Modulator	/	Unkown

Clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Phase
HY-13755	Sulforaphane	Inhibitor	99.75%	Phase 4
HY-13560	AVN-944	Modulator	99.89%	Phase 2
HY-18006	NKP608	Inhibitor	99.88%	Phase 2
HY-168739	Topoisomerase I inhibitor 17	Activator	/	Phase 2
HY-165550	Sphingosine	Inhibitor	/	Phase 1

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P991883	Metuzumab	Modulator	/	Phase 4

Pre-clinical Phase

Bioactive Molecules (167)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-107202	Polyinosinic-polycytidylic acid		99.40%	Unkown
HY-N0171A	Beta-Sitosterol (purity>98%)		99.74%	Unkown
HY-103269	BAI1	Inhibitor	99.68%	Unkown
HY-107202A	Poly (I:C):Kanamycin (1:1)		48.6%	Unkown
HY-W250111	Carboxymethyl chitosan	Activator	90%	Unkown
HY-P0081	Bax inhibitor peptide V5	Inhibitor	99.90%	Unkown
HY-N0361	Dihydrocapsaicin	Modulator	99.93%	Unkown
HY-N0674	Dehydrocorydaline	Modulator	99.77%	Unkown
HY-B1971	Deltamethrin		99.96%	Unkown
HY-120079	MSN-125	Inhibitor	99.67%	Unkown
HY-13755A	(R)-Sulforaphane	Inhibitor	99.95%	Unkown
HY-P1928	Humanin	Inhibitor	99.73%	Unkown
HY-N0060B	(E)-Ferulic acid	Activator	99.82%	Unkown
HY-123054	BTSA1	Activator	99.77%	Unkown
HY-157334	DEG-77	Activator	99.03%	Unkown
HY-N6626	Pyraclostrobin		99.91%	Unkown
HY-N0831	Jaceosidin	Activator	99.51%	Unkown
HY-118948	MSN-50	Inhibitor	98.09%	Unkown
HY-126437	Poly-L-lysine hydrobromide (MW 30000-70000)	Inhibitor	/	Unkown
HY-W082785A	L6H21	Modulator	99.19%	Unkown
HY-13108	Bz 423	Activator	99.72%	Unkown
HY-P2970	Stem bromelain	Modulator	/	Unkown
HY-N6801	Nivalenol	Activator	99.9%	Unkown
HY-N6005	Methyl caffeate	Modulator	99.89%	Unkown
HY-N2067	Vanillyl alcohol		99.68%	Unkown
HY-P1380A	Difopein TFA	Inhibitor	95.35%	Unkown
HY-N0475	Triptophenolide	Activator	99.98%	Unkown
HY-N0699	Daphnoretin	Inhibitor	99.83%	Unkown
HY-101310	SYM 2081	Activator	98.0%	Unkown
HY-126421	Kansuinine A	Modulator	99.81%	Unkown
HY-N0566	23-Hydroxybetulinic acid		99.44%	Unkown
HY-N0905	Ginsenoside Rh4	Activator	99.28%	Unkown
HY-N1983	Caudatin		99.95%	Unkown
HY-157176	BAX-IN-1	Inhibitor	98.05%	Unkown
HY-N0307	Ciwujianoside B	Inhibitor	99.68%	Unkown
HY-15341	BAM7	Activator	99.20%	Unkown
HY-N5008	Macranthoside B	Modulator	99.95%	Unkown
HY-N2135	Puerarin 6''-O-Xyloside		99.81%	Unkown
HY-132173	GL0388	Activator	99.22%	Unkown
HY-W674241	4-Ethylphenyl sulfate		/	Unkown
HY-147929	Apoptotic agent-3	Activator	98.19%	Unkown
HY-148368	CYD-4-61	Activator	99.92%	Unkown
HY-N1423B	Glycocholic acid hydrate	Modulator	99.85%	Unkown
HY-N1157	Thevetiaflavone	Modulator	99.83%	Unkown
HY-N0320	Salvianolic acid D	Modulator	95.15%	Unkown
HY-N7905	Myricetin 3'-glucoside	Inhibitor	99.98%	Unkown
HY-147785	Pim-1 kinase inhibitor 2	Modulator	99.91%	Unkown
HY-101996	SMBA1	Agonist	99.5800%	Unkown
HY-172262	WEHI-3773	Inhibitor	99.89%	Unkown
HY-N0882	Desacetylcinobufotalin	Modulator	99.41%	Unkown
HY-W072962	WX2-43	Activator	98.74%	Unkown
HY-119979	Cardanol monoene		98.02%	Unkown
HY-147889	BBR-BODIPY	Activator	98.15%	Unkown
HY-161659	Apoptosis inducer 19	Modulator	98.31%	Unkown
HY-N10144	Shinpterocarpin		/	Unkown
HY-122760	Bax activator-1	Activator	98.45%	Unkown
HY-108164	Aspidin BB	Modulator	98.02%	Unkown
HY-N9802	n-Butyl-β-D-fructofuranoside	Activator	97.0%	Unkown
HY-146548	Anticancer agent 43	Inducer	98.58%	Unkown
HY-141876	PRT543	Activator	/	Unkown
HY-180154	EGFR/BRAFV600E-IN-6		/	Unkown
HY-136893	SP-6-27	Activator	/	Unkown
HY-183312	Antitumor agent-217	Inhibitor	/	Unkown
HY-175019	VEGFR-2-IN-70	Agonist	/	Unkown
HY-175815	Apoptosis inducer 44	Inhibitor	/	Unkown
HY-126311	4-Hydroxyresveratrol	Inducer	/	Unkown
HY-146105	Anticancer agent 65	Modulator	/	Unkown
HY-168877	FMP		/	Unkown
HY-175227	STAT3/NF-κB-IN-1	Inhibitor	/	Unkown
HY-175021	HDAC-IN-91	Inhibitor	/	Unkown
HY-170912	Topo I/II-IN-2		/	Unkown
HY-119408	MB725	Activator	/	Unkown
HY-N8617	Trijuganone C	Activator	/	Unkown
HY-183772	TBC1D2-IN-1	Modulator	/	Unkown
HY-179022	CAIX/CDK-2-IN-1	Inhibitor	/	Unkown
HY-179520	XSJ151	Modulator	/	Unkown
HY-N17440	2-Methoxyjuglone	Modulator	/	Unkown
HY-175332	Apoptosis inducer 43	Inhibitor	/	Unkown
HY-15668	ST09	Activator	/	Unkown
HY-144792	Bcl-2-IN-7	Modulator	/	Unkown
HY-162360	EGFR-IN-109	Inhibitor	/	Unkown
HY-174469	PROTAC PI3K/110β degrader-2	Inhibitor	/	Unkown
HY-180274	JAK1/2-IN-3		/	Unkown
HY-149517	EGFR/BRAFV600E-IN-2	Activator	/	Unkown
HY-180324	Candidone	Inhibitor	/	Unkown
HY-151429	Antitumor agent-77	Inhibitor	/	Unkown
HY-P11374	Bid BH3-Gly-r8	Ligand	/	Unkown
HY-P10993	CT20p		/	Unkown
HY-177208	BW-AQ-113		/	Unkown
HY-151428	Antitumor agent-78	Inhibitor	/	Unkown
HY-170929	EMT inhibitor-3		/	Unkown
HY-172394	ZSNI-21	Modulator	/	Unkown
HY-183330	Topo I/II-IN-3	Inhibitor	/	Unkown
HY-181659	EGFR-IN-201	Inhibitor	/	Unkown
HY-181174	Antioxidant agent-22		/	Unkown
HY-184116	A2AR/EGFR-IN-1	Modulator	/	Unkown
HY-181015	α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu	Modulator	/	Unkown
HY-179155	PI3K/mTOR-IN-19	Inhibitor	/	Unkown
HY-178142	Multi-kinase-IN-7	Inhibitor	/	Unkown
HY-184386	Aurora kinase-IN-15	Modulator	/	Unkown
HY-143235	BRD4 Inhibitor-15	Modulator	/	Unkown
HY-182360	Cytisine-platinum(IV) prodrug-1		/	Unkown
HY-181060	Apoptosis inducer 56	Modulator	/	Unkown
HY-180823	Topoisomerase II/EGFR-IN-2	Inhibitor	/	Unkown
HY-183327	PI3K/mTOR-IN-22		/	Unkown
HY-P10992	YVPGP	Modulator	/	Unkown
HY-108919	CG-1521	Inhibitor	95.71%	Unkown
HY-P3148	Astin B	Modulator	95.0%	Unkown
HY-184301	EGFR/HER2-IN-20	Activator	/	Unkown
HY-178104	HDAC-IN-93	Inhibitor	/	Unkown
HY-144791	Bcl-2-IN-6	Modulator	/	Unkown
HY-180190	Tubulin polymerization-IN-85		/	Unkown
HY-181599	XAN-5		/	Unkown
HY-181248	BChE-IN-49	Inhibitor	/	Unkown
HY-N10313	Dehydrobruceine B	Modulator	/	Unkown
HY-N6799	Neosolaniol	Activator	99.72%	Unkown
HY-N17816	Tambulin	Inhibitor	/	Unkown
HY-179157	MA203	Modulator	/	Unkown
HY-117652	Lobetyol	Modulator	/	Unkown
HY-146253	CDK1/2/4-IN-1	Activator	/	Unkown
HY-182937	FLC-8	Modulator	/	Unkown
HY-183069	FKL-137	Modulator	/	Unkown
HY-186248	BCS12	Inhibitor	/	Unkown
HY-181019	iMPZ-8		/	Unkown
HY-181673	ICD inducer-2		/	Unkown
HY-172886	PI3K-IN-58	Modulator	/	Unkown
HY-175037	DNH28	Inhibitor	/	Unkown
HY-182349	Bax activator-2	Activator	/	Unkown
HY-167237	Calactin	Modulator	/	Unkown
HY-N12999	Stigmast-5-en-3-ol		/	Unkown
HY-174855	PI3K/mTOR-IN-17	Inhibitor	/	Unkown
HY-175020	QNX-10		/	Unkown
HY-180242	EGFR/CDK2-IN-5	Modulator	/	Unkown
HY-147928	Apoptotic agent-2	Activator	/	Unkown
HY-181769	Anticancer agent 306	Modulator	/	Unkown
HY-174419	TFSeB	Activator	/	Unkown
HY-178942	EGFR/VEGFR2-IN-9	Inhibitor	/	Unkown
HY-181477	ERK5-IN-7	Modulator	/	Unkown
HY-150540	Bcl-2-IN-10	Inhibitor	/	Unkown
HY-168623	EGFR-IN-134	Inhibitor	/	Unkown
HY-184448	CIB-Q22	Modulator	/	Unkown
HY-147514	Anticancer agent 64	Modulator	/	Unkown
HY-175588	EGFR-IN-170		/	Unkown
HY-183791A	Ferroptosis/apoptosis inducer-5	Modulator	/	Unkown
HY-184250	FGFR-IN-28	Modulator	/	Unkown
HY-181675	CHNQD-01522	Activator	/	Unkown
HY-181061	COX/5-LO-IN-2	Modulator	/	Unkown
HY-N0831R	Jaceosidin (Standard)	Activator	/	Unkown
HY-183355	KRAS G12D-IN-37		/	Unkown
HY-180150	PROTAC BRD4 Degrader-42	Activator	/	Unkown
HY-183369	VEGFR/PD-L1-IN-1	Activator	/	Unkown
HY-179614	PARP1-IN-50		/	Unkown
HY-181837	IKKβ-IN-7	Modulator	/	Unkown
HY-180196	EGFR-IN-187		/	Unkown
HY-181717	TKL002	Inhibitor	98.08%	Unkown
HY-107272	Chuanbeinone		/	Unkown
HY-P1380	Difopein	Inhibitor	/	Unkown
HY-178099	Apoptosis inducer 45	Inhibitor	/	Unkown
HY-184145	AKT1-IN-13	Inhibitor	/	Unkown
HY-N1326	Santamarine		98.85%	Unkown
HY-184446	CDC25A/NF-κB-IN-1	Modulator	/	Unkown
HY-179052	Apoptosis inducer 50	Activator	/	Unkown
HY-116267	MHY219		/	Unkown
HY-119682	Bax agonist 1		/	Unkown
HY-122481	Thaspine acetate		/	Unkown
HY-N8508	Myrothecine A	Inducer	/	Unkown
HY-N15466	Longan cerebroside II		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	BAX	VGNC	VGNC:70230
Felis catus	BAX	VGNC	VGNC:69139
Rattus norvegicus	BAX	RGD	RGD:2192
Mus musculus	BAX	MGD	MGI:99702
Canis familiaris	BAX	VGNC	VGNC:38388
Bos taurus	BAX	VGNC	VGNC:26428
Others	BAX	NCBI