MCL1 - MCL1 apoptosis regulator, BCL2 family member Gene

Also Known as TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 4170

About MCL1

Cytogenetic location: 1q21.2 Genomic coordinates (GRCh38): 1:150,574,558-150,579,610 (from NCBI)

This gene has 8 transcripts (splice variants), 238 orthologues and 8 paralogues. Ubiquitous expression in bone marrow (RPKM 341.7), gall bladder (RPKM 276.1) and 25 other tissues.

Summary

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 Family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting Apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote Apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]

MCL1 Products (3)

mRNA	Protein	Name
NM_021960.5	NP_068779.1	induced myeloid leukemia cell differentiation protein Mcl-1 isoform 1
NM_182763.3	NP_877495.1	induced myeloid leukemia cell differentiation protein Mcl-1 isoform 2
NM_001197320.2	NP_001184249.1	induced myeloid leukemia cell differentiation protein Mcl-1 isoform 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables BH3 domain binding	IPI IPI: Inferred from physical interaction	21036904	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	15901672	GOA
enables protein heterodimerization activity	IPI IPI: Inferred from physical interaction	10837489	GOA

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within DNA damage response	IMP IMP: Inferred from mutant phenotype	20467439	GOA
involved in extrinsic apoptotic signaling pathway in absence of ligand	IMP IMP: Inferred from mutant phenotype	16543145	GOA
involved in negative regulation of anoikis	IMP IMP: Inferred from mutant phenotype	22277751	GOA
involved in negative regulation of apoptotic process	IDA IDA: Inferred from direct assay	20041405	GOA
involved in negative regulation of autophagy	IMP IMP: Inferred from mutant phenotype	24113155	GOA
involved in negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	IMP IMP: Inferred from mutant phenotype	20921992	GOA
involved in positive regulation of apoptotic process	IDA IDA: Inferred from direct assay	21132008	GOA
involved in positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	IGI IGI: Inferred from genetic interaction	23858059	GOA
involved in regulation of apoptotic process	IDA IDA: Inferred from direct assay	18209102	GOA
acts upstream of or within response to cytokine	IDA IDA: Inferred from direct assay	9184696	GOA

Cellular Component GO Annotation	Evidence	References	Source
part of Bcl-2 family protein complex	IDA IDA: Inferred from direct assay	21199865	GOA
part of Bcl-2 family protein complex	IPI IPI: Inferred from physical interaction	20066663	GOA
located in membrane	IDA IDA: Inferred from direct assay	7896880	GOA
located in mitochondrion	IDA IDA: Inferred from direct assay	7896880	GOA
located in nucleus	IDA IDA: Inferred from direct assay	20467439	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MCL1 Protein Structure

Bcl-2

0
100
200
300
350 a.a.

Protein Preferred Names	Protein Names
induced myeloid leukemia cell differentiation protein Mcl-1	BCL2 family apoptosis regulator MCL1, BCL2 family apoptosis regulator bcl-2-like protein 3 bcl-2-related protein EAT/mcl1 myeloid cell leukemia 1 myeloid cell leukemia ES myeloid cell leukemia sequence 1 (BCL2-related)

MCL1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Cross	MCL1	Q07820	Cav1	Mus musculus	P49817	Anti Bait CoIP	22277751
Intra	MCL1	Q07820	USP9X	Homo sapiens	Q93008	Anti Bait CoIP	20023629
Intra	MCL1	Q07820	USP9X	Homo sapiens	Q93008	Anti Tag CoIP	20023629
Intra	MCL1	Q07820	USP9X	Homo sapiens	Q93008	Enzymatic Study	20023629
Intra	MCL1	Q07820	BMF	Homo sapiens	Q96LC9	Y2H Array	32296183
Intra	MCL1	Q07820	BMF	Homo sapiens	Q96LC9	Y2H Prey Pooling	32296183
Intra	MCL1	Q07820	BMF	Homo sapiens	Q96LC9	Validated Y2H	32296183
Intra	MCL1	Q07820	BAX	Homo sapiens	Q07812	Anti Tag CoIP	33961781
Intra	MCL1	Q07820	BAX	Homo sapiens	Q07812	X-Ray Diffraction	21199865
Intra	MCL1	Q07820	BAX	Homo sapiens	Q07812	Anti Bait CoIP	17525735
Intra	MCL1	Q07820	BAX	Homo sapiens	Q07812	Anti Tag CoIP	19968986
Intra	MCL1	Q07820	BAX	Homo sapiens	Q07812	Fluorescence	21458670
Intra	MCL1	Q07820	BID	Homo sapiens	P55957	Anti Tag CoIP	33961781
Intra	MCL1	Q07820	BID	Homo sapiens	P55957	Anti Bait CoIP	19074266
Intra	MCL1	Q07820	BID	Homo sapiens	P55957	FPS	16697956
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Anti Bait CoIP	20023629
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Anti Tag CoIP	33961781
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Anti Bait CoIP	18040043
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Anti Tag CoIP	28514442
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Validated Y2H	32296183
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Y2H Prey Pooling	32296183
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Y2H Array	32296183
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Anti Bait CoIP	22516262
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Anti Tag CoIP	15901672
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Anti Tag CoIP	19968986
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Anti Bait CoIP	15901672
Intra	MCL1	Q07820	BAK1	Homo sapiens	Q16611	Anti Bait CoIP	21132008
Intra	MCL1	Q07820	BBC3	Homo sapiens	Q9BXH1	Anti Bait CoIP	22516262
Intra	MCL1	Q07820	BBC3	Homo sapiens	Q9BXH1	Anti Tag CoIP	28514442
Intra	MCL1	Q07820	BBC3	Homo sapiens	Q9BXH1-2	Anti Tag CoIP	26431330
Intra	MCL1	Q07820	BBC3	Homo sapiens	Q9BXH1-2	Anti Bait CoIP	26431330
Intra	MCL1	Q07820	BCL2L11	Homo sapiens	O43521	Anti Bait CoIP	22516262
Intra	MCL1	Q07820	BCL2L11	Homo sapiens	O43521	Anti Tag CoIP	16213503
Intra	MCL1	Q07820	BCL2L11	Homo sapiens	O43521	Anti Bait CoIP	26859456
Intra	MCL1	Q07820	BCL2L11	Homo sapiens	O43521	Anti Bait CoIP	17525735
Intra	MCL1	Q07820	BCL2L11	Homo sapiens	O43521	Anti Bait CoIP	20085765
Intra	MCL1	Q07820	BCL2L11	Homo sapiens	O43521	Anti Bait CoIP	21132008
Intra	MCL1	Q07820	CAV1	Homo sapiens	Q03135	Anti Bait CoIP	22277751
Intra	MCL1	Q07820	CAV1	Homo sapiens	Q03135	Confocal	22277751
Intra	MCL1	Q07820	HUWE1	Homo sapiens	Q7Z6Z7	Anti Bait CoIP	20023629
Intra	MCL1	Q07820	HUWE1	Homo sapiens	Q7Z6Z7	Anti Tag CoIP	20023629
Intra	MCL1	Q07820	HUWE1	Homo sapiens	Q7Z6Z7	Anti Tag CoIP	33961781
Intra	MCL1	Q07820	HUWE1	Homo sapiens	Q7Z6Z7	Anti Tag CoIP	16213503
Intra	MCL1	Q07820	KCNF1	Homo sapiens	Q9H3M0	Y2H Prey Pooling	32296183
Intra	MCL1	Q07820	KCNF1	Homo sapiens	Q9H3M0	Validated Y2H	32296183
Intra	MCL1	Q07820	KCNF1	Homo sapiens	Q9H3M0	Y2H Array	32296183
Intra	MCL1	Q07820	PMAIP1	Homo sapiens	Q13794	SPR	21454712
Intra	MCL1	Q07820	PMAIP1	Homo sapiens	Q13794	Anti Bait CoIP	20085765
Intra	MCL1	Q07820	PMAIP1	Homo sapiens	Q13794	Anti Tag CoIP	33961781
Intra	MCL1	Q07820	PMAIP1	Homo sapiens	Q13794	Anti Bait CoIP	21132008
Intra	MCL1	Q07820	PMAIP1	Homo sapiens	Q13794	Pull Down	21454712
Intra	MCL1	Q07820	PMAIP1	Homo sapiens	Q13794	Anti Tag CoIP	15901672
Intra	MCL1	Q07820	STX8	Homo sapiens	Q9UNK0	Validated Y2H	32296183
Cross	MCL1	Q07820	q91au0_9hepc	Hepatitis C virus	Q91AU0	Anti Tag CoIP	19605477

Cross: Cross-species interaction Intra: Intraspecies interaction

MCL1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80508	MCL1 Antibody (YA303)	WB, ICC/IF, IHC-P, IP, FC	Human, Mouse
HY-P84507	MCL1 Antibody (YA4204)	WB, IHC-P, ICC/IF, ELISA	Human
HY-P84507A	MCL1 Antibody (YA4204)(PBS only)	WB, IHC-P, ICC/IF, ELISA	Human
HY-P85269	MCL1 Antibod (YA4961)	WB; ICC/IF; IP; FC	Human, Mouse, Rat
HY-P86177	MCL1 Antibody (YA5869)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Hepatocellular Carcinoma	Liver Cancer Primary Liver Cancer HCC Hepatoma Malignant Neoplasm Of Liver Liver Neoplasms Cancer, Hepatocellular Liver Cell Carcinoma Lcc Hepatoblastoma, Somatic Hepatic Cancer Primary Malignant Neoplasm Of Liver Rare Tumor Of Liver And Intrahepatic Biliary Tract Hepatocellular Carcinoma, Somatic Hepatocellular Carcinoma, Childhood Type, Somatic Hepatocellular Cancer, Somatic Ca Liver - Primary Hepatic Neoplasm Malignant Hepato-Biliary Neoplasm Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary Malignant Neoplasm Of Liver, Primary Malignant Tumor Of Liver Neoplasm Of Liver Non-Resectable Primary Hepatic Malignant Neoplasm Resectable Malignant Neoplasm Of Liver Resectable Malignant Neoplasm Of The Liver Primary Liver Carcinoma Primary Malignant Liver Neoplasm Primary Cancer Of Liver Primary Tumor Of The Liver Rare Tumor Of Liver And Ibt Hepatocellular Cancer Neoplasm Of The Liver Hepatomas Liver Neoplasm Liver Carcinoma Liver And Intrahepatic Biliary Tract Carcinoma Malignant Hepatobiliary Neoplasm Adult Primary Hepatocellular Carcinoma Hepatoblastoma Carcinoma Of Liver Malignant Liver Tumour Malignant Hepatic Tumour
Glioblastoma	Glioblastoma Multiforme Gbm Adult Glioblastoma Multiforme Grade Iv Adult Astrocytic Tumor Primary Glioblastoma Multiforme Spongioblastoma Multiforme Adult Glioblastoma Primary Glioblastoma
Mature B-Cell Neoplasm	Mature B-Cell Lymphocytic Neoplasm Neoplasm Of Mature B-Cells Mature B-Cell Non-Hodgkin Neoplasm With Leukaemic Behaviour
Squamous Cell Carcinoma, Head And Neck	Squamous Cell Carcinoma Of The Head And Neck HNSCC Head And Neck Squamous Cell Carcinoma Head And Neck Cancer Squamous Cell Carcinoma Of Lip Squamous Cell Carcinoma, Head And Neck, Somatic Carcinoma Of The Head And Neck Squamous Cell Carcinomas Of Head And Neck Scchn Squamous Cell Carcinoma Of The Hypopharynx Squamous Cell Carcinoma Of The Oropharynx Squamous Cell Carcinoma Of Salivary Glands Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses Squamous Cell Carcinoma Of The Oral Cavity Squamous Cell Carcinoma Of The Lip Carcinoma, Squamous Cell Of Head And Neck Lip Squamous Cell Carcinoma Cancer, Head/Neck Carcinoma, Squamous Cell, Head And Neck Salivary Gland Squamous Cell Carcinoma Cancer Of Head And Neck Squamous Cell Carcinoma Of Oropharynx Nos
Myeloid Leukemia	Myeloid Leukaemia Leukaemia Myelogenous Leukemia Myelogenous Myeloid Granulocytic Leukaemia Myeloid Granulocytic Leukemia Non-Lymphocytic Leukemia Leukemia, Myeloid Granulocytic Leukaemia Myelogenous Leukaemia Myeloid Leukaemia, Unspecified, Without Mention Of Remission
Leukemia, Chronic Myeloid	Chronic Myeloid Leukemia Chronic Myelogenous Leukemia CML Chronic Granulocytic Leukemia Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib Chronic Myeloid Leukaemia Chronic Granulocytic Leukaemia Chronic Myelogenous Leukaemia Myeloid Leukemia, Chronic Leukemia, Chronic Myelogenous Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic Cml - Chronic Myelogenous Leukemia Cgl Chronic Myelocytic Leukemia Leukemia, Chronic Myeloid, Atypical ACML Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative Myeloid Leukemia Chronic Leukemia, Myeloid, Chronic Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative Cml- [Chronic Myeloid Leukaemia] Cgl - [Chronic Granulocytic Leukaemia] Chronic Myelocytic Leukaemia
Lymphoma	Lymphoid Cancer Lymphomas Lymphoid Cancers Lymphoid Neoplasm Lymphoma Nos Nhl - [Non-Hodgkin Lymphoma] Non-Hodgkin Lymphoma Non-Hodgkin Lymphoma, Nos Non-Hodgkin Malignant Lymphoma Nos
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Gastric Cancer	Stomach Cancer Stomach Carcinoma Gastric Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Primary Biliary Cholangitis	Primary Biliary Cirrhosis Biliary Liver Cirrhosis Chronic Nonsuppurative Destructive Cholangitis Familial Primary Biliary Cirrhosis Pbc Hanot Syndrome Cholestatic Cirrhosis Biliary Cirrhosis Primary Liver Cirrhosis, Biliary Hanot'S Cirrhosis Biliary Cirrhosis Pericholangiolic Biliary Cirrhosis Tannhauser-Magendantz Syndrome Hanot-Rossle Syndrome Hypertrophic Cirrhosis Todd Cirrhosis Hanot Cirrhosis Charcot Cirrhosis Mahon-Tannhauser Syndrome Toxic Cirrhosis Hypertrophic Biliary Cirrhosis Monolobular Cirrhosis Unilobar Cirrhosis Xanthomatous Biliary Cirrhosis
Embryonal Carcinoma	Embryonal Neoplasm Embryonal Cancer Primary Extragonadal Embryonal Carcinoma Embryo Neoplasm Carcinoma Embryonal Cancer Embryonal Carcinoma, Embryonal Extragonadal Embryonal Carcinoma Cancer, Embryonal
Leukemia, Chronic Lymphocytic 2	Leukemia, Chronic Lymphocytic, Susceptibility To, 2 B-Cell Malignancy, Low-Grade Clls2 Disrupted In B-Cell Malignancy Dbm Leukemia, Chronic Lymphocytic, B-Cell Bcll Lymphocytic Leukemia Chronic B-Cell Chronic Lymphocytic Leukemia Chronic Lymph Leukaemia Chronic Lymphatic Leukaemia Chronic Lymphocytic Leukaemia Chronic Lymphoid Leukaemia Lymphoplasmacytic Leukaemia
Rhabdomyosarcoma
Cholangiocarcinoma	Cholangiocarcinoma, Susceptibility To Extrahepatic Cholangiocarcinoma Intrahepatic Cholangiocarcinoma Chlc Chlc, Susceptibility To Cc Cholangiocarcinoma Of Biliary Tract Cholangiocellular Carcinoma Distal Cholangiocarcinoma Perihilar Cholangiocarcinoma Bile Duct Cancer Cca Adult Primary Cholangiocellular Carcinoma Bile Duct Carcinoma
Neuroblastoma	Nb Neuroblastoma, Susceptibility To Neuroblastomas Central Neuroblastoma
Follicular Lymphoma	Lymphoma, Follicular Lymphoma Follicular Brill-Symmers' Disease Large Cell Follicular Non-Hodgkin Lymphoma Diffuse Follicle Centre Lymphoma Diffuse Follicular Lymphoma Nos Follicular Nodular Non-Hodgkin Lymphoma, Unspecified Follicular Large Cell Cleaved Or Noncleaved Lymphoma Large Cell Follicular Noncleaved Lymphoma Follicular Lymphoma With Or Without Diffuse Areas Histiocytic Follicular Lymphoma Histiocytic Nodular Lymphoma Histiocytic Nodular Malignant Lymphoma Large Cell Follicular Lymphoma Large Cell Noncleaved Follicular Lymphoma Large Cell Noncleaved Follicular Malignant Lymphoma Nodular Reticulum Cell Sarcoma Noncleaved Follicular Lymphoma
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Leukemia, Acute Lymphoblastic	Acute Lymphoblastic Leukemia ALL Acute Lymphocytic Leukemia Leukemia, Acute Lymphocytic, Susceptibility To, 1 Acute Lymphoblastic Leukaemia Precursor Lymphoblastic Lymphoma/Leukemia Precursor Lymphoid Neoplasm Leukemia, Acute Lymphoblastic, Susceptibility To B-Cell Acute Lymphoblastic Leukemia Leukemia, Acute Lymphocytic 1 Acute Lymphocytic Leukaemia Acute Lymphoblastic Leukemia/Lymphoma All1 Childhood Acute Lymphoblastic Leukemia Leukemia Acute Lymphoblastic 1 Leukemia Acute Lymphoblastic B-Hyperdiploid Leukemia Acute Lymphocytic Leukemia Acute Lymphocytic 1 Leukemia B-Cell Acute Lymphoblastic Leukemia T-Cell Acute Lymphoblastic Leukemia, Acute Lymphoblastic, 3 ALL3 Lymphoblastic Leukemia Acute Leukemia, Acute, Lymphoblastic Precursor Cell Lymphoblastic Leukemia Lymphoma Leukemia, Lymphocytic, Acute, L1 Leukemia, Acute Lymphoblastic, Susceptibility To, 3
Common Bile Duct Neoplasm	Common Bile Duct Neoplasms Neoplasm Of Common Bile Duct
Anaplastic Large Cell Lymphoma	Alcl Cd30 Positive Anaplastic Large Cell Lymphoma Ki-1 Positive Anaplastic Large Cell Lymphoma Primary Systemic Alcl Sacl Ki-1+ Anaplastic Large Cell Lymphoma
Melanoma	Malignant Melanoma Cutaneous Melanoma Naevocarcinoma Malignant Melanomas
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Cancer Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Lymphoma, Hodgkin, Classic	Hodgkin Lymphoma Hodgkin Disease Hodgkin'S Lymphoma Hodgkins Lymphoma Classic Hodgkin Lymphoma CHL Hodgkin Lymphoma, Susceptibility To Hl Hodgkin'S Sarcoma Stage I Subdiaphragmatic Hodgkin Lymphoma Stage Ii Subdiaphragmatic Hodgkin Lymphoma Lymphoma, Hodgkin'S Classic Hodgkin Disease Hodgkin'S Disease Lymphoma, Hodgkin, Susceptibility To Hodgkin'S Disease Of Intrapelvic Lymph Nodes Hodgkin'S Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb Malignant Lymphogranuloma Malignant Lymphogranulomatosis Malignant Hodgkin Lymphoma Classical Hodgkin Lymphoma, Type Not Specified
Acute Promyelocytic Leukemia	Leukemia, Acute Promyelocytic Acute Myeloblastic Leukemia Type 3 Aml M3 APL Leukemia, Acute Promyelocytic, Somatic Aml With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Apml Acute Myeloblastic Leukemia 3 Acute Myeloid Leukemia With T(15 17)(Q22 Q12) (Pml/Raralpha) And Variants Acute Myeloblastic Leukaemia Type 3 Acute Myeloid Leukaemia M3 Acute Myeloid Leukemia M3 Acute Promyelocytic Leukaemia M3 Anll Myeloid Leukemia, Acute, M3 Leukemia Promyelocytic Acute Leukemia, Promyelocytic, Acute Leukemia, Acute, Promyelocytic
Autosomal Dominant Intellectual Developmental Disorder 8	Autosomal Dominant Non-Syndromic Intellectual Disability 8 Mental Retardation, Autosomal Dominant 8 Autosomal Dominant Mental Retardation 8 Mrd8
Cervical Adenoid Cystic Carcinoma	Adenoid Cystic Carcinoma Of The Cervix Uteri
Myelodysplastic Syndrome	Myelodysplastic Syndromes Myelodysplasia MDS Myelodysplastic Syndrome Included Myelodysplastic Syndrome, Susceptibility To, Included Myelodysplastic Syndrome, Somatic Myelodysplastic Syndrome, Susceptibility To
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Peripheral Nervous System Disease	Peripheral Neuropathy Peripheral Nerve Disease Peripheral Nerve Disorders Neuropathy, Peripheral Peripheral Neuropathy Due To Vitamin Pyridoxine Hyperalimentation
Basal Cell Carcinoma	Basal Cell Cancer Basal Cell Neoplasm Basal Cell Carcinoma Of Skin Malignant Basal Cell Tumor Basal Cell Tumor Epithelioma Basal Cell Malignant Basal Cell Neoplasm Rodent Ulcer Carcinoma Basal Cell Neoplasms, Basal Cell Basal Cell Carcinomas Experimental Organism Basal Cell Carcinoma Nodulo-Ulcerative Basal Cell Carcinoma Basalioma Basal Cell Epithelioma Of Skin Bcc - [Basal Cell Carcinoma] Of Skin Rodent Ulcer Of Skin Rodent Ulcer Of Unspecified Site Basal Cell Epithelioma Of Unspecified Site
Chlamydia	Chlamydial Infection Chlamydia Trachomatis Infectious Disease Chlamydial Disease Chlamydia Infections
Peripheral T-Cell Lymphoma	Lymphoma T-Cell Peripheral
B-Cell Lymphoma	Lymphoma, B-Cell B-Cell Lymphomas B-Cell Lymphocytic Neoplasm Lymphoma B-Cell B-Cell Lymphoma Nos
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Oligodendroglioma	Oligodendroglial Neoplasm Oligodendroglial Tumor Oligodendroglial Tumors Well Differentiated Oligodendroglioma
Myeloma, Multiple	Multiple Myeloma Kahler Disease Myelomatosis Plasma Cell Myeloma Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler'S Disease Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Protection Against Lung Cancer, Susceptibility To Adenocarcinoma Of Lung, Somatic Nonsmall Cell Lung Cancer Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Esophageal Cancer	Esophageal Carcinoma Carcinoma Of Esophagus Esophageal Squamous Cell Carcinoma, Somatic Esophageal Carcinoma, Somatic Esophagus Cancer Gastric Cardia Adenocarcinoma Esophageal Neoplasms Esophageal Cancer, Somatic Cancer Of Esophagus Cancer Of Oesophagus Carcinoma Of Oesophagus Ca Lower Third Oesophagus Ca Middle Third Oesophagus Malignant Neoplasm Of Distal Third Of Esophagus Malignant Neoplasm Of Lower Third Of Oesophagus Malignant Neoplasm Of Middle Third Of Oesophagus Malignant Neoplasm Of Proximal Third Of Esophagus Malignant Neoplasm Of Upper Third Esophagus Malignant Tumor Of Abdominal Esophagus Malignant Tumor Of Distal Third Of Esophagus Malignant Tumor Of Proximal Third Of Esophagus Malignant Tumor Of The Middle Third Of The Esophagus ESCR Aerodigestive Tract Cancer Escc Esophageal Squamous Cell Carcinoma Cancer, Esophageal Malignant Neoplasm Of Esophagus Squamous Cell Carcinoma Of Esophagus Malignant Neoplasm Of Middle Third Of Esophagus
Mantle Cell Lymphoma	Lymphoma, Mantle Cell Lcm Mcl Mantle Zone Lymphoma Lymphoma Mantle-Cell Lymphoma, Mantle-Cell Malignant Lymphoma, Lymphocytic, Intermediate Differentiation, Diffuse Malignant Lymphoma - Lymphocytic, Intermediate Differentiation Diffuse Small Cleaved-Cell Lymphoma Diffuse Small Cleaved Cell Malignant Lymphoma Small Cleaved Cell Non-Hodgkin Lymphoma Diffuse Non-Hodgkin Small Cleaved Cell Lymphoma Malignant Lymphomatous Polyposis Malignant Small Cell, Noncleaved, Diffuse Lymphoma Malignant Undifferentiated Cell, Non-Burkitt Lymphoma Cleaved Cell Lymphoma Small Cell Mantle Cell Lymphoma Small Cleaved Cell Malignant Lymphoma
Leukemia	Leukemias Leukaemia, Unspecified, Without Mention Of Remission Aleukemic Leukaemia Chronic Leukaemia Subacute Leukaemia Leukaemia Disorder Leukaemia Nos
Apocrine Adenosis Of Breast	Apocrine Adenosis Of The Breast
Mesothelioma, Malignant	Malignant Mesothelioma Pleural Mesothelioma MESOM Mesothelioma, Somatic Advanced Malignant Mesothelioma Asbestos-Related Malignant Mesothelioma Diffuse Malignant Mesothelioma Malignant Tumor Of Mesothelium Malignant Mesothelioma, Susceptibility To Mesothelioma Diffuse Malignant Mesothelioma Malignant Pleural Mesothelioma
Lymphoma, Non-Hodgkin, Familial	Non-Hodgkin Lymphoma Lymphoma, Non-Hodgkin NHL Lymphoma, Non-Hodgkin, Somatic Lymphoma, Follicular, Somatic Familial Non-Hodgkin Lymphoma Lymphoma Non-Hodgkins Follicular Lymphoma, Somatic Lymphosarcoma Non-Hodgkins Lymphoma
Bone Marrow Cancer	Malignant Neoplasm Of Bone Marrow Bone Marrow Neoplasm Bone Marrow Tumor Malignant Bone Marrow Tumor Myeloproliferative Disorders Bone Marrow Neoplasms Myeloproliferative Disease Chronic Myeloproliferative Disorder
Leukocyte Disease	Leukocyte Disorders
Pancreatic Cancer	Pancreatic Carcinoma Familial Pancreatic Carcinoma Pancreatic Neoplasm Carcinoma Of Pancreas Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Cancer Of The Pancreas Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Leukemia, Myeloid, Acute Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Clinical Phase
Pre-clinical Phase

Clinical Phase

Bioactive Molecules (23)

Cat. No.	Product Name	Effect	Purity	Phase
HY-112041	Unesbulin		99.17%	Phase 3
HY-101533	AZD-5991	Inhibitor	99.79%	Phase 2
HY-112218	MIK665	Inhibitor	99.11%	Phase 2
HY-X0009	Tambiciclib		99.68%	Phase 2
HY-15464	(R)-(-)-Gossypol		99.37%	Phase 2
HY-15464A	(R)-(-)-Gossypol acetic acid		98.93%	Phase 2
HY-138697	S65487		99.91%	Phase 2
HY-X0009A	Tambiciclib dimaleate		99.53%	Phase 2
HY-138697A	S65487 sulfate		99.35%	Phase 2
HY-138697B	S65487 hydrochloride		98.54%	Phase 2
HY-15163A	Zotiraciclib hydrochloride	Inhibitor	/	Phase 2
HY-10358	MK-2206 dihydrochloride		99.99%	Phase 1
HY-149672	ABBV-467	Inhibitor	99.78%	Phase 1
HY-12422	Voruciclib	Inhibitor	99.76%	Phase 1
HY-101565	Tapotoclax	Inhibitor	99.53%	Phase 1
HY-103019B	(-)-Enitociclib		99.85%	Phase 1
HY-12422A	Voruciclib hydrochloride	Inhibitor	99.26%	Phase 1
HY-109184	Murizatoclax	Inhibitor	98.84%	Phase 1
HY-101533B	AZD-5991 (S-enantiomer)	Inhibitor	99.83%	Phase 1
HY-139453A	LP-284		/	Phase 1
HY-19471	(rac)-ZK-304709		/	Phase 1
HY-103019BR	(-)-Enitociclib (Standard)		/	Phase 1
HY-10358R	MK-2206 dihydrochloride (Standard)		/	Phase 1

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P991225	BI-1206	Antagonist	96.82%	Phase 2

Pre-clinical Phase

Bioactive Molecules (161)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-100741	S63845	Inhibitor	99.94%	Unkown
HY-114855	BT2	Inhibitor	99.81%	Unkown
HY-N0662	Amentoflavone		99.66%	Unkown
HY-108232	MK-2206		99.72%	Unkown
HY-N0087	Gambogic Acid		98.34%	Unkown
HY-103019	Enitociclib		99.89%	Unkown
HY-18628	UMI-77	Inhibitor	99.66%	Unkown
HY-123954	BTX-A51		98.58%	Unkown
HY-101972	AZ-PFKFB3-67	Inhibitor	97.03%	Unkown
HY-N0763	Angelicin		99.98%	Unkown
HY-12468	A-1210477		99.86%	Unkown
HY-14985	BAY 61-3606 dihydrochloride		99.45%	Unkown
HY-118341	Clitocine		95.88%	Unkown
HY-W040129	Chromomycin A3		99.66%	Unkown
HY-N0831	Jaceosidin		99.51%	Unkown
HY-W008296	NH2-C6-NH-Boc		99.77%	Unkown
HY-125876	PROTAC Bcl2 degrader-1	Inhibitor	99.80%	Unkown
HY-103019A	(±)-Enitociclib		99.23%	Unkown
HY-125877	PROTAC Mcl1 degrader-1	Inhibitor	98.13%	Unkown
HY-164515	ONC213		99.89%	Unkown
HY-12020	TW-37	Inhibitor	99.50%	Unkown
HY-129478	TC11		99.55%	Unkown
HY-76474A	BAY 61-3606 hydrochloride		98.08%	Unkown
HY-162919	YK-2168		98.05%	Unkown
HY-153803	GBD-9	Degrader	99.91%	Unkown
HY-15191	Sabutoclax	Inhibitor	99.80%	Unkown
HY-112859	VU0661013	Inhibitor	98.45%	Unkown
HY-N8146	Bruceantinol	Inhibitor	98.89%	Unkown
HY-122627	CLZ-8		99.14%	Unkown
HY-100741A	(S,R)-S63845	Control	98.09%	Unkown
HY-129700	MCL-1/BCL-2-IN-2	Inhibitor	99.05%	Unkown
HY-149007	STAT3-IN-11		98.29%	Unkown
HY-119271	CMLD010509		99.11%	Unkown
HY-117203A	CDK12-IN-E9	Inhibitor	99.71%	Unkown
HY-129681	MCL-1/BCL-2-IN-1	Inhibitor	98.65%	Unkown
HY-162858	BRD-810		98.00%	Unkown
HY-101778	ML311	Inhibitor	98.98%	Unkown
HY-112591	NSC260594		97.50%	Unkown
HY-100741C	(R,R)-S63845	Control	99.32%	Unkown
HY-120113	SC-2001		99.37%	Unkown
HY-P2343	BH3 hydrochloride	Activator	98.03%	Unkown
HY-128360	dMCL1-2		99.29%	Unkown
HY-132307	Mcl-1 inhibitor 6		98.77%	Unkown
HY-123955	Casein Kinase inhibitor A86		99.26%	Unkown
HY-155472	Mcl-1 inhibitor 17	Inhibitor	99.41%	Unkown
HY-15613	Maritoclax	Inhibitor	99.97%	Unkown
HY-16695	MIM1	Inhibitor	98.0%	Unkown
HY-178226	PBX-7016	Inhibitor	/	Unkown
HY-158783	SACLAC		99.70%	Unkown
HY-167881	MLS-0053105	Inhibitor	98.89%	Unkown
HY-129702	MCL-1/BCL-2-IN-4	Inhibitor	99.95%	Unkown
HY-160438B	PBX-7011 TFA	Inhibitor	98.60%	Unkown
HY-176142	YX0798		98.90%	Unkown
HY-164460	AZD1897	Inhibitor	99.69%	Unkown
HY-19551	Apogossypolone		98.58%	Unkown
HY-101533A	AZD-5991 Racemate	Inhibitor	/	Unkown
HY-12826	IMB-XH1	Inhibitor	98.0%	Unkown
HY-129701	MCL-1/BCL-2-IN-3	Inhibitor	98.93%	Unkown
HY-13408	(+)-Apogossypol	Inhibitor	/	Unkown
HY-182312	CTX-439		/	Unkown
HY-RS08230	MCL1 Human Pre-designed siRNA Set A		/	Unkown
HY-12527	Pyridoclax	Inhibitor	99.95%	Unkown
HY-15191B	(S)-Sabutoclax	Inhibitor	98.03%	Unkown
HY-16669	Mcl1-IN-1	Inhibitor	98.02%	Unkown
HY-76474	BAY 61-3606		98.21%	Unkown
HY-112218A	(R)-MIK665	Inhibitor	/	Unkown
HY-125908	A-1210477-piperazinyl	Ligand	/	Unkown
HY-128607	Mcl1-IN-9	Inhibitor	/	Unkown
HY-100762	Mcl1-IN-11	Inhibitor	/	Unkown
HY-100763	Mcl1-IN-12	Inhibitor	/	Unkown
HY-10357	MK-2206 free base		/	Unkown
HY-111537	rel-AZ5576	Inhibitor	/	Unkown
HY-130261	Mcl-1 antagonist 1	Antagonist	/	Unkown
HY-133015	Mcl-1 inhibitor 3	Inhibitor	/	Unkown
HY-145825	Mcl-1 inhibitor 7	Inhibitor	/	Unkown
HY-145825A	(E)-Mcl-1 inhibitor 7	Inhibitor	/	Unkown
HY-146097	RMS5		/	Unkown
HY-111467	Mcl1-IN-4	Inhibitor	/	Unkown
HY-111468	Mcl1-IN-3	Inhibitor	/	Unkown
HY-115928	M24	Inhibitor	/	Unkown
HY-116220	Mcl1-IN-14		/	Unkown
HY-122721	Mcl1-IN-5	Inhibitor	/	Unkown
HY-122759	CPA-7		/	Unkown
HY-123034	CDKI-83		/	Unkown
HY-123564	Mcl1-IN-7	Inhibitor	/	Unkown
HY-124846	MI-223	Modulator	/	Unkown
HY-125718	MLS-2384 free base		/	Unkown
HY-144428	Bcl-2/Mcl-1-IN-2	Inhibitor	/	Unkown
HY-144430	Bcl-2/Mcl-1-IN-1	Inhibitor	/	Unkown
HY-144431	Bcl-2/Mcl-1-IN-3	Inhibitor	/	Unkown
HY-145826	Mcl-1 inhibitor 8	Inhibitor	/	Unkown
HY-148203	Mcl-1 inhibitor 9	Inhibitor	/	Unkown
HY-148899	Mcl-1 inhibitor 10	Inhibitor	/	Unkown
HY-149495	CP-07	Degrader	/	Unkown
HY-150507	JNJ-4355	Inhibitor	/	Unkown
HY-153423	Mcl-1 inhibitor 12	Inhibitor	/	Unkown
HY-153423A	Mcl-1 inhibitor 13	Inhibitor	/	Unkown
HY-154961	Mcl-1 inhibitor 14		/	Unkown
HY-154962	Mcl-1 inhibitor 15	Inhibitor	/	Unkown
HY-155012	Mcl-1 inhibitor 16	Inhibitor	/	Unkown
HY-155153	CDK9-IN-24		/	Unkown
HY-155245	A09-003	Inhibitor	/	Unkown
HY-15867	Meayamycin B		/	Unkown
HY-159513	Bcl-2/Mcl-1-IN-4	Inhibitor	/	Unkown
HY-159588	Mcl-1 inhibitor 20	Inhibitor	/	Unkown
HY-161274	Bfl-1-IN-1	Inhibitor	/	Unkown
HY-161732	GQN-B37-E	Inhibitor	/	Unkown
HY-161733	GQN-B37-Me	Inhibitor	/	Unkown
HY-162619	CDK9-IN-33		/	Unkown
HY-162780	Mcl-1-IN-19	Inhibitor	/	Unkown
HY-163293	Mcl-1 inhibitor 18	Inhibitor	/	Unkown
HY-163681	Zamzetoclax	Inhibitor	/	Unkown
HY-164452	A-1155905		/	Unkown
HY-164453	A-1248767		/	Unkown
HY-169797	STAT3-IN-38		/	Unkown
HY-170762	Mcl-1 inhibitor 21	Inducer	/	Unkown
HY-170762A	(+)-Mcl-1 inhibitor 21	Inducer	/	Unkown
HY-170762B	(-)-Mcl-1 inhibitor 21	Inducer	/	Unkown
HY-170763	Mcl-1 inhibitor 22	Inducer	/	Unkown
HY-170763A	(+)-Mcl-1 inhibitor 22	Inducer	/	Unkown
HY-170763B	(-)-Mcl-1 inhibitor 22		/	Unkown
HY-171334A	P1D-34		/	Unkown
HY-173065	CDK9-IN-36		/	Unkown
HY-178008	Mcl-1-IN-16		/	Unkown
HY-178010	Mcl-1-IN-17	Inhibitor	/	Unkown
HY-178499	CDK9-IN-44	Inhibitor	/	Unkown
HY-178910	Mcl-1-IN-20		/	Unkown
HY-179023	CDK9-IN-45		/	Unkown
HY-179633	ZLMT-72		/	Unkown
HY-180190	Tubulin polymerization-IN-85		/	Unkown
HY-181054	Mcl-1-IN-21		/	Unkown
HY-181078	Cephalotaxine-ester-(R)-1-ethoxy-3-mercaptopropan-2-ol-Ph(3,4OMe)		/	Unkown
HY-181587	PDGFRA/CAIX/XII-IN-1		98.10%	Unkown
HY-181746	Bcl-2/Mcl-1-IN-5		/	Unkown
HY-181767	PROTAC HDAC3 degrader-1		/	Unkown
HY-182671	SRX3305		/	Unkown
HY-183328	MNK1/2-IN-11	Inhibitor	/	Unkown
HY-183601	Mcl-1-IN-22		/	Unkown
HY-183601A	Mcl-1-IN-22 hydrochloride		/	Unkown
HY-184160	Mcl1 Degrader-1		/	Unkown
HY-184310	Mcl-1-IN-23		/	Unkown
HY-18628S	UMI-77-d4	Inhibitor	/	Unkown
HY-N0831R	Jaceosidin (Standard)		/	Unkown
HY-N16746	Nordentatin	Inhibitor	/	Unkown
HY-N17676	3-Tridecylphenol		/	Unkown
HY-N3913	Furowanin A	Inhibitor	/	Unkown
HY-P4095	NoxaBH3		/	Unkown
HY-RS08231	Mcl1 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS08232	Mcl1 Rat Pre-designed siRNA Set A		/	Unkown
HY-W043574	6-Ethyl-7-hydroxy-4-methyl-2H-chromen-2-one	Inhibitor	/	Unkown
HY-W689801	A-1208746		/	Unkown
HY-103019AR	(±)-Enitociclib (Standard)		/	Unkown
HY-115529	(-)BI97D6	Inducer	/	Unkown
HY-116532	YCW-E11	Inhibitor	/	Unkown
HY-119009	TM-233	Inhibitor	/	Unkown
HY-119271A	(-)-CMLD010509		/	Unkown
HY-121638B	(E/Z)-CU-3		/	Unkown
HY-13551C	Amsacrine isethionate		/	Unkown
HY-13551D	Amsacrine lactate		/	Unkown
HY-164468	Ch282-5	Inhibitor	/	Unkown
HY-W286906	Mcl1-IN-15		/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P991899	IKS03 Antibody		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MCL1	VGNC	VGNC:68211
Mus musculus	MCL1	MGD	MGI:101769
Canis familiaris	MCL1	VGNC	VGNC:43079
Rattus norvegicus	MCL1	RGD	RGD:620525
Macaca mulatta	MCL1	VGNC	VGNC:74679
Others	MCL1	NCBI