RMS5
RMS5, a tetrandrine analogue, is a potent P-glycoprotein (P-gp) inhibitor. RMS5 has markedly antiproliferative and cytotoxic effects on cancer cells. RMS5 slightly diminishes the expression of the anti-apoptotic Bcl-2 family proteins Bcl-XL and Mcl-1. RMS3 causes PARP cleavage, a marker for cells undergoing apoptosis. RMS5 has strong anticancer property.
For research use only. We do not sell to patients.
- CAS No.: 2497686-68-5
- Formula: C35H38N2O5S
- Molecular Weight:598.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2497686-68-5
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Molecular Weight 598.75
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Formula C35H38N2O5S
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SMILES
COC1=C(OC(C=C([C@@]2([H])CC3=CC=C(C=C3)O4)C(CCN2C)=C5)=C5OC)C([C@]6([H])CC7=CC4=CS7)=C(CCN6C)C=C1OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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