Bcl-2/Mcl-1-IN-4
Bcl-2/Mcl-1-IN-4 (compound 20) is a dual inhibitor targeting Bcl-2 (Ki=0.49 μM) and Mcl-1 (Ki=0.51 μM). Bcl-2/Mcl-1-IN-4 significantly inhibits cancer cell proliferation and effectively induces apoptosis in U937 cells. Bcl-2/Mcl-1-IN-4 can be used in cancer research.
For research use only. We do not sell to patients.
- Formula: C34H27BrN4O8S2
- Molecular Weight:763.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Bcl-2 0.49 μM (Ki) |
Mcl-1 0.51 μM (Ki) |
Chemical Information
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Molecular Weight 763.63
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Formula C34H27BrN4O8S2
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SMILES
O=C(NS(=O)(C1=CC=C([N+]([O-])=O)C=C1)=O)[C@@H](NC(CN2C(/C(SC2=O)=C/C3=CC=C(C4=CC=C(C)C=C4)C=C3)=O)=O)CC5=CC=C(Br)C=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)