CDK9-IN-44
CDK9-IN-44 (Compound 7) is a selective CDK9 inhibitor (IC50=7.6 μM). CDK9-IN-44 inhibits CDK9/cyclin T1 kinase activity, blocking transcriptional elongation, reducing the expression of pro-cancer proteins (such as MCL1, c-MYC), and inducing tumor cell apoptosis. CDK9-IN-44 is promising for research of glioblastoma (GBM) and central nervous system (CNS) disorders.
For research use only. We do not sell to patients.
- Formula: C22H18O7
- Molecular Weight:394.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CDK9 7.6 μM (IC50) |
MCL1 |
Chemical Information
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Molecular Weight 394.37
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Formula C22H18O7
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SMILES
OC1=CC=C(C2=COC3=C([C@H]([C@H]4CCCO4)CC(O5)=O)C5=CC(O)=C3C2=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)