1. Apoptosis
  2. Bcl-2 Family
  3. Sabutoclax

Sabutoclax (Synonyms: BI-97C1)

Cat. No.: HY-15191
Handling Instructions

Sabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC50s of 0.32 μM, 0.31 μM, 0.20 μM, and 0.62 μM, respectively.

For research use only. We do not sell to patients.

Sabutoclax Chemical Structure

Sabutoclax Chemical Structure

CAS No. : 1228108-65-3

Size Price Stock Quantity
5 mg USD 380 In-stock
Estimated Time of Arrival: December 31
10 mg USD 600 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1250 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1850 In-stock
Estimated Time of Arrival: December 31
100 mg USD 2850 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Sabutoclax is a potent and effective Bcl-2 Family (Bcl-2, Bcl-XL, Mcl-1, Bfl-1) inhibitor with IC50s of 0.32 μM, 0.31 μM, 0.20 μM, and 0.62 μM, respectively.

IC50 & Target

Bcl-xL

0.31 μM (IC50)

BCL2

0.32 μM (IC50)

Mcl-1

0.2 μM (IC50)

Bfl-1

0.62 μM (IC50)

Molecular Weight

700.78

Formula

C₄₂H₄₀N₂O₈

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 36.67 mg/mL (52.33 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4270 mL 7.1349 mL 14.2698 mL
5 mM 0.2854 mL 1.4270 mL 2.8540 mL
10 mM 0.1427 mL 0.7135 mL 1.4270 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.75 mg/mL (3.92 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Sabutoclax
Cat. No.:
HY-15191
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