Mcl1-IN-7
Mcl1-IN-7 (compound 11) is a reversible covalent inhibitor of Mcl-1 with the activity of inhibiting Mcl-1. By covalently targeting the non-catalytic lysine side chain of Mcl-1, it has higher potency than non-covalent counterparts and can be used to develop Mcl-1 inhibitory compounds and study related biological phenomena.
For research use only. We do not sell to patients.
- CAS No.: 2012563-34-5
- Formula: C36H34BN3O7
- Molecular Weight:631.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MOLP-8 | IC50 |
0.075 μM
Compound: 56
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Cytotoxicity against human MOLP8 cells by caspase-3/7 activation
Cytotoxicity against human MOLP8 cells by caspase-3/7 activation
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[PMID: 33333396] |
Chemical Information
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CAS No. 2012563-34-5
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Molecular Weight 631.48
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Formula C36H34BN3O7
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SMILES
O=CC1=CC(OCC2=NN(C)C(C)=C2C3=CC=CC4=C3N(C)C(C(O)=O)=C4CCCOC5=CC=CC6=C5C=CC=C6)=CC=C1B(O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mcl1-IN-7 Related Classifications
HY-123564 Related Classifications
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