CDK9-IN-36
CDK9-IN-36 (Compound T7) is a potent, selective and metabolically stable CDK9 inhibitor with an IC50 value of 1.2 nM. CDK9-IN-36 effectively suppresses cell proliferation, reduces colony formation, and induces apoptosis in Osimertinib (HY-15772)-resistant NSCLC cells by downregulating Mcl-1. CDK9-IN-36 also demonstrates antitumor efficacy in a tumor xenograft model.
For research use only. We do not sell to patients.
- Formula: C30H33F2N5O4
- Molecular Weight:565.61
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
|
CDK9 1.2 nM (IC50) |
Chemical Information
-
Molecular Weight 565.61
-
Formula C30H33F2N5O4
-
SMILES
FC1=C(C2=CC(OCCCCCCO3)=C(C=C2)F)N=C(NC4=CC=C(C(NC5CCN(C(C)=O)CC5)=O)C3=C4)N=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz