MCL-1/BCL-2-IN-3
Based on 1 Customer Validation
MCL-1/BCL-2-IN-3 (Compound 2) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectively.
For research use only. We do not sell to patients.
- Purity: 98.93%
- CAS No.: 2163793-55-1
- Formula: C27H25BrN2O5S
- Molecular Weight:569.47
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
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Anti-Blood Cancer Compound Library
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Mitochondria-Targeted Compound Library
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Highly Selective Inhibitors Library
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Anti-Hematopathy Compound Library
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Anti-Ovarian Cancer Compound Library
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Mitophagy Compound Library
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MCE Bioactive Compound Library
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High-Throughput Bioactive Compound Library
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Biological Activity
Chemical Information
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CAS No. 2163793-55-1
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Appearance Solid
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Molecular Weight 569.47
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Formula C27H25BrN2O5S
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Color Light yellow to yellow
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SMILES
O=C(OC)CCCCC(NCCN(C(C1=CC=C(SC2=CC=C(Br)C=C2)C3=CC=CC4=C13)=O)C4=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 17.86 mg/mL (31.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.7560 mL | 8.7801 mL | 17.5602 mL | 43.9005 mL |
| 5 mM | 0.3512 mL | 1.7560 mL | 3.5120 mL | 8.7801 mL | |
| 10 mM | 0.1756 mL | 0.8780 mL | 1.7560 mL | 4.3900 mL | |
| 15 mM | 0.1171 mL | 0.5853 mL | 1.1707 mL | 2.9267 mL | |
| 20 mM | 0.0878 mL | 0.4390 mL | 0.8780 mL | 2.1950 mL | |
| 25 mM | 0.0702 mL | 0.3512 mL | 0.7024 mL | 1.7560 mL | |
| 30 mM | 0.0585 mL | 0.2927 mL | 0.5853 mL | 1.4633 mL |
MCL-1/BCL-2-IN-3 Related Classifications
HY-129701 Related Classifications
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