1. Apoptosis
  2. c-Myc
    Apoptosis
  3. CMLD010509

CMLD010509 (Synonyms: SDS-1-021)

Cat. No.: HY-119271
Handling Instructions

CMLD010509 (SDS-1-021) is a highly specific inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1. CMLD010509 (SDS-1-021) shows an IC50 below 10 nM for most MM cell lines and induces apoptosis. CMLD010509 (SDS-1-021) is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism.

For research use only. We do not sell to patients.

CMLD010509 Chemical Structure

CMLD010509 Chemical Structure

CAS No. : 256497-58-2

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Description

CMLD010509 (SDS-1-021) is a highly specific inhibitor of the oncogenic translation program supporting multiple myeloma (MM)-including key oncoproteins such as MYC, MDM2, CCND1, MAF, and MCL-1. CMLD010509 (SDS-1-021) shows an IC50 below 10 nM for most MM cell lines and induces apoptosis. CMLD010509 (SDS-1-021) is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism[1].

Molecular Weight

556.40

Formula

C₂₇H₂₆BrNO₇

CAS No.

256497-58-2

SMILES

O=C([[email protected]]([[email protected]]1C2=CC=CC=C2)[[email protected]@H](O)[[email protected]]3(O)[[email protected]@]1(C4=CC=C(Br)C=C4)OC5=CC(OC)=CC(OC)=C35)NOC

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

CMLD010509SDS-1-021CMLD 010509CMLD-010509c-MycApoptosisMycInhibitorinhibitorinhibit

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