Mcl-1-IN-19
Mcl-1-IN-19 (compound 26) binds to Mcl-1, with the Ki of 86 pM. Mcl-1-IN-19 inhibits growth in H929 cells with the GI of 43 nM.
For research use only. We do not sell to patients.
- Formula: C47H51Cl2N5O7
- Molecular Weight:868.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| K562 | GI50 |
>12000 nM
Compound: 26
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Growth inhibition of human K562 cells measured after 72 to 96 hrs by cell-titer glo assay
Growth inhibition of human K562 cells measured after 72 to 96 hrs by cell-titer glo assay
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[PMID: 39102508] |
| NCI-H1048 | GI50 |
2.3 μM
Compound: 26
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Growth inhibition of human NCI-H1048 cells measured after 72 to 96 hrs by cell-titer glo assay
Growth inhibition of human NCI-H1048 cells measured after 72 to 96 hrs by cell-titer glo assay
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[PMID: 39102508] |
| NCI-H929 | GI50 |
43 nM
Compound: 26
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Growth inhibition of human NCI-H929 cells measured after 72 to 96 hrs by cell-titer glo assay
Growth inhibition of human NCI-H929 cells measured after 72 to 96 hrs by cell-titer glo assay
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[PMID: 39102508] |
Chemical Information
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Molecular Weight 868.84
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Formula C47H51Cl2N5O7
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SMILES
ClC1=CC=C(C2=C1C3=C(N=C(N=C3C)C)C)C(CCCOC4=CC(C)=C(C(C)=C4)Cl)=C5N2[C@@H](CN(C5=O)C6=CC(OCC7CCOCC7)=C(C8=C6N(C(C(O)=O)=C8)C)OC)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mcl-1-IN-19 Related Classifications
HY-162780 Related Classifications
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