A-1155905
A-1155905 is a MCL-1 inhibitor (IC50=33.5 nM; Ki=0.58 nM) with anticancer activity. A-1155905 selectively binds to MCL-1 with sufficient affinity to disrupt the MCL-1-bim complex in living cells. A-1155905-induced death of MCL-1-dependent cell lines is caspase-dependent and occurs via apoptosis.
For research use only. We do not sell to patients.
- CAS No.: 2228052-37-5
- Formula: C46H51FN6O6
- Molecular Weight:802.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Caspase Isoforms
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Biological Activity
Chemical Information
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CAS No. 2228052-37-5
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Molecular Weight 802.93
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Formula C46H51FN6O6
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SMILES
O=C(C)N(CC1)CCN1C2=CC=C(OCC3=C(C4=C(N(CCN5CCOCC5)C(C(O)=O)=C6CCCOC7=C(C=CC=C8F)C8=CC=C7)C6=CC=C4)C(C)=NN3C)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)