MCL-1/BCL-2-IN-4
Based on 1 Customer Validation
MCL-1/BCL-2-IN-4 (Compound 7) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 2163793-56-2
- Formula: C26H23BrN2O5S
- Molecular Weight:555.44
-
Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
-
CAS No. 2163793-56-2
-
Appearance Solid
-
Molecular Weight 555.44
-
Formula C26H23BrN2O5S
-
Color Light yellow to yellow
-
SMILES
O=C(O)CCCCC(NCCN(C(C1=CC=C(SC2=CC=C(Br)C=C2)C3=CC=CC4=C13)=O)C4=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (180.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8004 mL | 9.0019 mL | 18.0037 mL | 45.0094 mL |
| 5 mM | 0.3601 mL | 1.8004 mL | 3.6007 mL | 9.0019 mL | |
| 10 mM | 0.1800 mL | 0.9002 mL | 1.8004 mL | 4.5009 mL | |
| 15 mM | 0.1200 mL | 0.6001 mL | 1.2002 mL | 3.0006 mL | |
| 20 mM | 0.0900 mL | 0.4501 mL | 0.9002 mL | 2.2505 mL | |
| 25 mM | 0.0720 mL | 0.3601 mL | 0.7201 mL | 1.8004 mL | |
| 30 mM | 0.0600 mL | 0.3001 mL | 0.6001 mL | 1.5003 mL | |
| 40 mM | 0.0450 mL | 0.2250 mL | 0.4501 mL | 1.1252 mL | |
| 50 mM | 0.0360 mL | 0.1800 mL | 0.3601 mL | 0.9002 mL | |
| 60 mM | 0.0300 mL | 0.1500 mL | 0.3001 mL | 0.7502 mL | |
| 80 mM | 0.0225 mL | 0.1125 mL | 0.2250 mL | 0.5626 mL | |
| 100 mM | 0.0180 mL | 0.0900 mL | 0.1800 mL | 0.4501 mL |