Mcl-1-IN-17
Mcl-1-IN-17 (Compound 25) is an orally active Myeloid Cell Leukemia 1 (Mcl-1) inhibitor with a Ki < 0.08 nM. Mcl-1-IN-17 has a significant antiproliferative activity (GI50s of 39 and 105 nM for H929 and A427 cells, respectively) and inhibits cell apoptosis. Mcl-1-IN-17 can be used for hematological and solid cancers research.
For research use only. We do not sell to patients.
- Formula: C44H48Cl2N6O6
- Molecular Weight:827.79
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Mcl-1 <0.08 nM (Ki) |
Chemical Information
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Molecular Weight 827.79
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Formula C44H48Cl2N6O6
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SMILES
CC1=C(Cl)C(C)=CC(OCCCC2=C(C(N(C3=CC(OC)=C(OC)C4=C3N(CCCOC5)C(C(N(C)C)=O)=C4)C[C@H]6C)=O)N6C7=C2C=CC(Cl)=C7C(C5=N8)=CN8C)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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