country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-144431

Copy Link Print Information

Bcl-2/Mcl-1-IN-3

Name: Bcl-2/Mcl-1-IN-3
Brand: MedChemExpress
SKU: HY-144431
Availability: PreOrder

Bcl-2/Mcl-1-IN-3 (compound 1) is a Bcl-2/Mcl-1 inhibitor, with K_is of 0.14 μM and 0.23 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-3 can be used for the research of cancer.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2088981-53-5

Formule: C₂₇H₂₆ClNO₄

Masse moléculaire:463.95

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Bcl-2/Mcl-1-IN-3 Chemical Structure

CAS No.: 2088981-53-5

Fast delivery

Free and easy returns

Size

Prix

Stock

Quantité

MOQ

Minimum order quantity Minimum order quantity

Sample (0.1mg)

In-stock

(In Japan)

Apply Now

Obtenir un devis Ask For Quote & Lead Time Consult sales personnel for more information Check price and availability Obtenir un devis Ask For Quote & Lead Time Consult sales personnel for more information Check price and availability

Bulk Inquiry

Other size

Obtenir un devis Obtenir un devis

Get it by August 31for select sizes. Order within 11 hrs 49 mins.

Amount: USD 0.00

Please select quantity

or

or

* Veuillez sélectionner la quantité avant d'ajouter des articles.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

This product is a controlled substance, please contact local distributor for purchase. This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

Data Download

Data Sheet (268 KB)

Instruction de manipulation (2659 KB)

To place orders, for customer services and technical support, please contact:

609-228-6898

[email protected] [email protected]

Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec

Activité biologique

Chemical Information

Pureté et documentation

Références

Help & FAQs

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Voir tous les produits spécifiques à Isoform Bcl-2 Family
More

Bcl-2

Bcl-xL

Bcl-W

Mcl-1

Bfl-1

Bcl-B

Bax

Bak

Bim

BNIP3

Bad

Activité biologique

Description

IC₅₀ & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Classifications

Bioz

Activité biologique

Description

Bcl-2/Mcl-1-IN-3 (compound 1) is a Bcl-2/Mcl-1 inhibitor, with K_is of 0.14 μM and 0.23 μM for Mcl-1 and Bcl-2, respectively. Bcl-2/Mcl-1-IN-3 can be used for the research of cancer^[1].

IC₅₀ & Target
^[1]

Mcl-1

0.14 μM (Ki)

Bcl-2

0.23 μM (Ki)

Bcl-xL

15 μM (Ki)

Voir tous les produits spécifiques à Isoform Bcl-2 Family :

Bcl-2

Bcl-xL

Bcl-W

Mcl-1

Bfl-1

Bcl-B

Bax

Bak

Bim

BNIP3

Bad

Chemical Information

CAS No. 2088981-53-5

Masse moléculaire 463.95

Formule C₂₇H₂₆ClNO₄

SMILES

O=C(O)C1=CC=CC=C1COC2=CC=CC3=C2C=CN3CCCOC4=CC(C)=C(Cl)C(C)=C4

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Instruction de manipulation (2659 KB)

Références

[1]. Niu Q, et, al. Design, synthesis and biological evaluation of dual Bcl-2/Mcl-1 inhibitors bearing 2-(1H-indol-4-yl)benzoic acid scaffold. Bioorg Med Chem Lett. 2021 Sep 1;47:128215. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=
Concentration Concentration

×
Volume Volume

×
Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

×

Volume _(start) Volume _(start)

=

Concentration _(final) Concentration _(final)

×

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bcl-2/Mcl-1-IN-3 Related Classifications

HY-144431 Related Classifications

Apoptosis

Bcl-2 Family

Aires thérapeutique

Cancer

Cancer

Cancer Targeted Therapy Cancer Metabolism and Metastasis

Bioz

Powered by Bioz See more details on Bioz

Keywords

Bcl-2/Mcl-1-IN-3
2088981-53-5
Bcl-2 Family
Inhibitor
inhibitor
inhibit

Your Recently Viewed Products

Bcl-2/Mcl-1-IN-3

100 mg Obtenir un devis

Subscribe to the

MedChemExpress

Newsletter

Subscribe

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis

Please select quantity

Amount: USD 0.00

Activité biologique

Description

IC₅₀ & Target

Chemical Information

Pureté et documentation

Références

Sign in to MedChemExpress Sign In

Enregistrer

Sign in to MedChemExpress

Keep me logged in. Mot de passe oublié

Enregistrer un nouveau compte

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes

Check out faster

Add multiple shipping locations

View orders

Assay Types

1/16

Demande en ligne

Your information is safe with us. *Required Fields.

Nom du produit *
Field is required.

Requested Quantity *
Field is required.

Nom du demandeur *
Field is required.

Civilité *
Field is required.

Email *
Field is required.

Please enter a valid Email Address.

Numéro de téléphone *
Field is required.

Department

Nom de l''organisation *
Field is required.

Ville
Ville

Ville

Enter Others City *
Field is required.

Field is required.

Etat Etat *
Field is required.

Pays ou Région *
Field is required.

Container *
Field is required.

MCE Japan Authorized Agent:

ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社

Remarques

Request for Report

Please fill out this form to request the report. We will send it to your Email address shortly.
Your information is safe with us. *Required Fields.

Nom du produit *
Field is required.

Lot # *
Field is required.

Nom du demandeur *
Field is required.

Email *
Field is required.

Please enter a valid Email Address.

Numéro de téléphone
Field is required.

Department *
Field is required.

Nom de l''organisation *
Field is required.

Pays ou Région *
Field is required.

Remarques

Bulk Inquiry Request for Report Demande en ligne Avis client Request for Recombinant Proteins Catalog

We have received your request and will respond to you as soon as possible. Congratulations! Uh-oh!

We have received your inquiry regarding and will respond to you as soon as possible. We have received your request and will respond to you as soon as possible. Thank You for Your Feedback! This product is a controlled substance and not for sale in your territory. It appears that we were unable to send an email to . Please verify your email address and try again!

Inquiry Information

Nom du produit:

Cat. No.:

Quantité:

MCE Japan Authorized Agent:

Inquiry Information

Nom du produit:

CAS No.:

Species:

Pureté:

Quantité:

Licensing Opportunities

Your information is safe with us. *Required Fields.

Nom du demandeur *
Field is required.

Civilité *
Field is required.

Role/Position *
Field is required.

Nom de l''organisation *
Field is required.

Pays ou Région *
Field is required.

Etat Etat *
Field is required.

Email *
Field is required.

Please enter a valid Email Address.

Numéro de téléphone *
Field is required.

Nom du produit
Field is required.

CAS No.
Field is required.

Remarques

MedChemExpress

MedChemExpress

Contactez-nous

Qui sommes-nous

Siège social

Distributeurs

Déclaration sur le faux rapport

Carrières

Support pour client

Support pour client

Support technique

Services

Informations pour commander

Retour facile

Tarifs et conditions de livraison

Termes et conditions

Potentiel de propriété intellectuelle

Ressources

Ressources

Échantillons gratuits

Calculator Application

Revues scientifiques

Topics

Product Guides

Blogs

Protocols

Brochures

Promotions

Events and Webinars

Gènes

Biomedical Dictionary

Subscribe to our E-newsletter

Sorry, but the email address you supplied was invalid.

Thanks, your subscription has been confirmed. You will hear from us soon.

Submission failed, please try again later.

Les produits sont des réactifs chimiques destinés uniquement à la recherche et ne sont pas destinés à un usage humain. Nous ne vendons pas aux patients.

Copyright © 2013-2026 MedChemExpress. All Rights Reserved.

Carte du Site | Politique de Confidentialité

Online Service Online Customer Service

Contact Us

Happy to help!

MedChemExpress

Tel: 609-228-6898

E-mail: [email protected]

Technical Support: [email protected]

MedChemExpress

We use cookies

MedChemExpress values your privacy and your trust is important to us. We use cookies to enhance your website experience. Some cookies are necessary to run the website. Privacy and Cookie Policy

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent:

Bcl-2/Mcl-1-IN-3

Voir tous les produits spécifiques à Isoform Bcl-2 Family

Activité biologique

Description

IC50 & Target

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Bcl-2/Mcl-1-IN-3 Related Classifications

HY-144431 Related Classifications

Bioz

Keywords

Your Recently Viewed Products

IC₅₀ & Target