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Bax agonist 1

Bax agonist 1 (compound SMBA2) is a Bax agonist (Ki=57.2 nM). Bax agonist 1 induces Bax conformational changes by blocking S184 phosphorylation, promoting Bax insertion into the mitochondrial membrane and forming Bax oligomers, which induce cytochrome c release and apoptosis in malignant cancer cells expressing Bax. Bax agonist 1 can be used in lung cancer research.

For research use only. We do not sell to patients.

  • CAS No.: 18304-79-5
  • Formula: C8H16N4
  • Molecular Weight:168.24
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Bax agonist 1 Chemical Structure
    Bax agonist 1 Chemical Structure
CAS No.: 18304-79-5
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All Bcl-2 Family Isoforms

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  • Bax agonist 1