n-Butyl-β-D-fructofuranoside
Based on 1 Customer Validation
n-Butyl-β-D-fructofuranoside could be isolated from kangaisan. n-Butyl-β-D-fructofuranoside induces apoptosis through the mitochondrial pathway. n-Butyl-β-D-fructofuranoside can be used for cancer research.
For research use only. We do not sell to patients.
- Purity : 97.0%
- CAS No.: 80971-60-4
- Formula: C10H20O6
- Molecular Weight:236.26
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Description
IC50 & Target
[1]|
Bax |
Bcl-2 |
In Vitro
n-Butyl-β-D-fructofuranoside (0-23.6 μg/mL; 24-78 hours) has antiproliferation activity and inhibits the viability of Bel-7402 cells[1].
n-Butyl-β-D-fructofuranoside (0-75 μg/mL; 0-72 hours) inhibits BEL-7402 cells by interfering with cell cycle and inducing apoptosis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Bel-7402 cells
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Concentration:0.47, 2.95, 5.90, 11.8, 17.7 and 23.6 μg/mL
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Incubation Time:24, 48 and 72 hours
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Result:Inhibited the proliferation of Bel-7402 cells at both time- and dose-dependent manner.
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Cell Line:Bel-7402 cells
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Concentration:0, 50 and 75 μg/mL
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Incubation Time:24, 48 and 72 hours
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Result:Induced cell cycle arrest at G0/G1 phase.
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Cell Line:Bel-7402 cells
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Concentration:23.6 μg/mL
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Incubation Time:0, 24, 48 and 72 hours
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Result:Decreased Bcl-2 and increased Bax and p53 levels in a time manner.
Chemical Information
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CAS No. 80971-60-4
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Appearance Oil
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Molecular Weight 236.26
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Formula C10H20O6
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Color Light yellow to yellow
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SMILES
CCCCO[C@](O[C@@H]1CO)([C@H]([C@@H]1O)O)CO
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (423.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2326 mL | 21.1631 mL | 42.3263 mL | 105.8156 mL |
| 5 mM | 0.8465 mL | 4.2326 mL | 8.4653 mL | 21.1631 mL | |
| 10 mM | 0.4233 mL | 2.1163 mL | 4.2326 mL | 10.5816 mL | |
| 15 mM | 0.2822 mL | 1.4109 mL | 2.8218 mL | 7.0544 mL | |
| 20 mM | 0.2116 mL | 1.0582 mL | 2.1163 mL | 5.2908 mL | |
| 25 mM | 0.1693 mL | 0.8465 mL | 1.6931 mL | 4.2326 mL | |
| 30 mM | 0.1411 mL | 0.7054 mL | 1.4109 mL | 3.5272 mL | |
| 40 mM | 0.1058 mL | 0.5291 mL | 1.0582 mL | 2.6454 mL | |
| 50 mM | 0.0847 mL | 0.4233 mL | 0.8465 mL | 2.1163 mL | |
| 60 mM | 0.0705 mL | 0.3527 mL | 0.7054 mL | 1.7636 mL | |
| 80 mM | 0.0529 mL | 0.2645 mL | 0.5291 mL | 1.3227 mL | |
| 100 mM | 0.0423 mL | 0.2116 mL | 0.4233 mL | 1.0582 mL |