1. Apoptosis
    Protein Tyrosine Kinase/RTK
    Metabolic Enzyme/Protease
  2. Apoptosis
    MDM-2/p53
    ROS
    MMP
    Bcl-2 Family
  3. Anticancer agent 65

Anticancer agent 65 

Cat. No.: HY-146105
Handling Instructions

Anticancer agent 65 (compound 4c) shows excellent activity in cancer cell lines, especially A549 cells, with an IC50 of 1.07 μM. Anticancer agent 65 induces S-phase arrest in A549 cells and increases the expression level of p53 and p21. Anticancer agent 65 causes apoptosis, ROS generation and collapse of MMP in A549 cells.

For research use only. We do not sell to patients.

Anticancer agent 65 Chemical Structure

Anticancer agent 65 Chemical Structure

CAS No. : 2407861-48-5

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Anticancer agent 65 (compound 4c) shows excellent activity in cancer cell lines, especially A549 cells, with an IC50 of 1.07 μM. Anticancer agent 65 induces S-phase arrest in A549 cells and increases the expression level of p53 and p21. Anticancer agent 65 causes apoptosis, ROS generation and collapse of MMP in A549 cells[1].

IC50 & Target

MMP

 

Bcl-2

 

Bax

 

In Vitro

Anticancer agent 65 (compound 4c) increases the expression of Bax and decrease that of Bcl-2[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

589.89

Formula

C36H63NO5

CAS No.
SMILES
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Anticancer agent 65
Cat. No.:
HY-146105
Quantity:
MCE Japan Authorized Agent: