2. PI3K/Akt/mTOR Apoptosis Metabolic Enzyme/Protease Immunology/Inflammation NF-κB
  3. PI3K Akt Bcl-2 Family Apoptosis Reactive Oxygen Species (ROS) Lactate Dehydrogenase SOD
  4. α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu

α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu (Compound C) is an oligosaccharide. α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu activates the PI3K/AKT signaling pathway. α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu significantly inhibits Apoptosis by regulating the Bcl-2/BAX ratio. α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu shows cytoprotective activity by reducing ROS and LDH levels, decreasing MDA activity, and increasing CAT, SOD, and GSH activities. α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu shows neuroprotective effects and antioxidant capacity.

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α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu

α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu Chemical Structure

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α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu Related Antibodies

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Description

α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu (Compound C) is an oligosaccharide. α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu activates the PI3K/AKT signaling pathway. α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu significantly inhibits Apoptosis by regulating the Bcl-2/BAX ratio. α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu shows cytoprotective activity by reducing ROS and LDH levels, decreasing MDA activity, and increasing CAT, SOD, and GSH activities. α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu shows neuroprotective effects and antioxidant capacity[1].

IC50 & Target[1]

Bax

 

Bcl-2

 

Molecular Weight

504.44

Formula

C18H32O16
SMILES

O[C@@H]([C@@H]1O)[C@H](O[C@@H]([C@@H]1O)O[C@@H]2[C@H](O[C@@H]([C@H]([C@@H]2O)O)CO)O[C@H]3[C@@H]([C@H](OC([C@H]3O)O)CO)O)CO
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-GluPI3KAktBcl-2 FamilyApoptosisReactive Oxygen Species (ROS)Lactate DehydrogenaseSODPhosphoinositide 3-kinasePKBProtein kinase BLDHSuperoxide DismutaseNeuroprotectiveAntioxidantPC12Inhibitorinhibitorinhibit

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