BAX Antibody (YA825)

Cat. No.: HY-P80027: FAQs
Data Sheet SDS COA User Guide for Antibodies

BAX Antibody (YA825) is a non-conjugated and Mouse origined monoclonal antibody about 21 kDa, targeting to BAX. It can be used for WB, IHC-P assays with tag free, in the background of Human, Mouse, Rat.

For research use only. We do not sell to patients.

Size	Price	Stock	Quantity
Free Sample		Apply now
10 μL	$130	In-stock	Estimated Time of Arrival: December 31
50 μL	$340	In-stock	Estimated Time of Arrival: December 31
100 μL	$550	In-stock	Estimated Time of Arrival: December 31
250 μL		Get quote

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Biological Activity
Technical Parameters
Properties
Documentation

Description	BAX Antibody (YA825) is a non-conjugated and Mouse origined monoclonal antibody about 21 kDa, targeting to BAX. It can be used for WB, IHC-P assays with tag free, in the background of Human, Mouse, Rat.
Background	BAX: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. The association and the ratio of BAX to BCL2 also determines survival or death of a cell following an apoptotic stimulus. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Dec 2019]
Tag	Free
Gene ID	581
Synonyms	Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4
Molecular Weight	Predicted band size: 21 kDa
Purity	Protein A affinity purified.
Subcellular Location	Mitochondrion membrane, cytoplasm
Conjugation	Non-conjugated
Research Field	Cell Biology
Product Categories	Primary Antibody; Mouse Monoclonal Antibody
Host	Mouse
Reactivity	Human, Mouse, Rat
SwissProt ID	SwissProt: Q07812 Human;SwissProt: Q07813 Mouse
Dilution Ratio	WB: 1:500-1:1000 ;IHC: 1:50-1:100
Application	WB, IHC-P
Appearance	Liquid
Formulation	Supplied in 1*PBS (pH7.4), 0.2% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG2b
Immunogen	Synthetic peptide corresponding to Human BAX.The exact sequence is proprietary to MCE.
Documentation	Select Batch: Data Sheet (234 KB) SDS (251 KB) COA (206 KB) User Guide for Antibodies (1077 KB)

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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BAX Antibody (YA825)

Biological Activity

Technical Parameters

Properties

Documentation

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