2. Gene
  3. MISP - mitotic spindle positioning Gene

MISP - mitotic spindle positioning Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MISP1; C19orf21

Gene ID: 126353 | Gene type: protein coding

About MISP

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:748,438-764,318 (from NCBI)

This gene has 2 transcripts (splice variants), 136 orthologues and 1 paralogue. Biased expression in small intestine (RPKM 92.0), duodenum (RPKM 77.1) and 6 other tissues.

Summary

The protein encoded by this gene is an actin-bundling protein involved in determining cell morphology and mitotic progression. The encoded protein is required for the proper positioning of the mitotic spindle. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Feb 2016]

MISP Products(1)

mRNA Protein Name
NM_173481.4 NP_775752.1 mitotic interactor and substrate of PLK1

MISP Protein Structure

AKAP2_C

AKAP2_C: A-kinase anchor protein 2 C-terminus (325 - 674)

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  • 200
  • 400
  • 600
  • 679 a.a.
Protein Preferred Names Protein Names

mitotic interactor and substrate of PLK1

caprice

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Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08465 MISP Human Pre-designed siRNA Set A / Unkown
HY-RS08466 MISP3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris MISP VGNC VGNC:43246
Felis catus MISP VGNC VGNC:63519
Bos taurus MISP VGNC VGNC:31486
Rattus norvegicus MISP RGD RGD:1595680
Mus musculus MISP MGD MGI:1926156
Macaca mulatta MISP VGNC VGNC:74840