CTTNBP2NL - CTTNBP2 N-terminal like Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 55917

About CTTNBP2NL

Cytogenetic location: 1p13.2 Genomic coordinates (GRCh38): 1:112,391,087-112,461,164 (from NCBI)

This gene has 4 transcripts (splice variants), 270 orthologues and 3 paralogues. Ubiquitous expression in esophagus (RPKM 9.4), gall bladder (RPKM 9.0) and 23 other tissues.

Summary

Enables protein Phosphatase 2A binding activity. Acts upstream of or within negative regulation of transmembrane transport; negative regulation of transporter activity; and protein dephosphorylation. Located in actin Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

CTTNBP2NL Products (1)

mRNA Protein Name
NM_018704.3 NP_061174.1 CTTNBP2 N-terminal-like protein

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
18782753 GOA
enables protein phosphatase 2A binding IDA
IDA: Inferred from direct assay
24218568 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transmembrane transport IMP
IMP: Inferred from mutant phenotype
24218568 GOA
acts upstream of or within negative regulation of transporter activity IMP
IMP: Inferred from mutant phenotype
24218568 GOA
acts upstream of or within protein dephosphorylation IMP
IMP: Inferred from mutant phenotype
24218568 GOA
Cellular Component GO Annotation Evidence References Source
part of FAR/SIN/STRIPAK complex IDA
IDA: Inferred from direct assay
18782753 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CTTNBP2NL Protein Structure

CortBP2

CortBP2: Cortactin-binding protein-2 (3 - 188)

  • 0
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  • 500
  • 600
  • 639 a.a.
Protein Preferred Names Protein Names

CTTNBP2 N-terminal-like protein

CTTNBP2NL Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CTTNBP2NL Q9P2B4 STRN Homo sapiens O43815
BioID
24255178
Intra
CTTNBP2NL Q9P2B4 STRN Homo sapiens O43815
Anti Tag CoIP
18782753
Intra
CTTNBP2NL Q9P2B4 STRN3 Homo sapiens Q13033
Anti Tag CoIP
18782753
Intra
CTTNBP2NL Q9P2B4 STRN3 Homo sapiens Q13033
BioID
24255178
Intra
CTTNBP2NL Q9P2B4 STRIP1 Homo sapiens Q5VSL9
Anti Tag CoIP
18782753
Intra
CTTNBP2NL Q9P2B4 STRIP1 Homo sapiens Q5VSL9
BioID
24255178
Intra
CTTNBP2NL Q9P2B4 PKNOX2 Homo sapiens Q96KN3
Y2H Array
32296183
Intra
CTTNBP2NL Q9P2B4 PKNOX2 Homo sapiens Q96KN3
Y2H Prey Pooling
32296183
Intra
CTTNBP2NL Q9P2B4 STK26 Homo sapiens Q9P289
Anti Tag CoIP
18782753
Intra
CTTNBP2NL Q9P2B4 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra
CTTNBP2NL Q9P2B4 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
CTTNBP2NL Q9P2B4 MOB4 Homo sapiens Q9Y3A3
BioID
24255178
Intra
CTTNBP2NL Q9P2B4 MOB4 Homo sapiens Q9Y3A3
Anti Tag CoIP
18782753
Intra
CTTNBP2NL Q9P2B4 USHBP1 Homo sapiens Q8N6Y0
Y2H Prey Pooling
25416956
Intra
CTTNBP2NL Q9P2B4 STK24 Homo sapiens Q9Y6E0
Anti Tag CoIP
18782753
Intra
CTTNBP2NL Q9P2B4 HGS Homo sapiens O14964
Validated Y2H
25416956
Intra
CTTNBP2NL Q9P2B4 HGS Homo sapiens O14964
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03352 CTTNBP2NL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris CTTNBP2NL VGNC VGNC:39720
Bos taurus CTTNBP2NL VGNC VGNC:27823
Mus musculus CTTNBP2NL MGD MGI:1933137
Macaca mulatta CTTNBP2NL VGNC VGNC:71557
Rattus norvegicus CTTNBP2NL RGD RGD:1310822
Felis catus CTTNBP2NL VGNC VGNC:61275
Others CTTNBP2NL NCBI