2. Gene
  3. SNX18 - sorting nexin 18 Gene

SNX18 - sorting nexin 18 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as SNAG1; SH3PX2; SH3PXD3B

Gene ID: 112574 | Gene type: protein coding

About SNX18

This gene has 3 transcripts (splice variants), 271 orthologues and 15 paralogues. Ubiquitous expression in bone marrow (RPKM 13.6), ovary (RPKM 10.4) and 25 other tissues.

Summary

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a SH3 domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

SNX18 Products(3)

mRNA Protein Name
NM_001102575.2 NP_001096045.1 sorting nexin-18 isoform a
NM_001145427.2 NP_001138899.1 sorting nexin-18 isoform c
NM_052870.4 NP_443102.2 sorting nexin-18 isoform b

SNX18 Protein Structure

SH3_9

SH3_9: Variant SH3 domain (7 - 57)

PX

PX: PX domain (278 - 380)

BAR_3_WASP_bdg

BAR_3_WASP_bdg: WASP-binding domain of Sorting nexin protein (386 - 541)

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  • 628 a.a.
Protein Preferred Names Protein Names

sorting nexin-18

SH3 and PX domain-containing protein 3B

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13531 SNX18 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SNX18 MGD MGI:2137642
Canis familiaris SNX18 VGNC VGNC:46627
Macaca mulatta SNX18 VGNC VGNC:77738
Felis catus SNX18 VGNC VGNC:65548
Rattus norvegicus SNX18 RGD RGD:1310367
Bos taurus SNX18 VGNC VGNC:35098