RAB11FIP5 - RAB11 family interacting protein 5 Gene

Homo sapiens

Also known as GAF1; pp75; RIP11; gaf-1; rab11-FIP5

Gene ID: 26056 | Gene type: protein coding

About RAB11FIP5

Cytogenetic location: 2p13.2 Genomic coordinates (GRCh38): 2:73,073,382-73,112,948 (from NCBI)

This gene has 6 transcripts (splice variants), 285 orthologues and 2 paralogues. Broad expression in testis (RPKM 48.5), kidney (RPKM 16.7) and 18 other tissues.

Summary

Enables gamma-tubulin binding activity. Involved in cellular response to acidic pH; negative regulation of Adiponectin secretion; and regulation of protein localization to cell surface. Located in centriolar satellite and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022]

RAB11FIP5 Products(2)

mRNA	Protein	Name
NM_001371272.1	NP_001358201.1	rab11 family-interacting protein 5 isoform 1
NM_015470.3	NP_056285.1	rab11 family-interacting protein 5 isoform 2

RAB11FIP5 Protein Structure

RBD-FIP

0
100
200
300
400
500
600
653 a.a.

Protein Preferred Names

Protein Names

rab11 family-interacting protein 5

RAB11 family interacting protein 5 (class I)

Related Diseases

Diseases

Alias

Neonatal Lupus Erythematosus

Neonatal Systemic Lupus Erythematosus

Mucocutaneous Leishmaniasis

American Cutaneous Leishmaniasis	American Mucocutaneous Leishmaniasis
Cutaneous Leishmaniasis, American	Mucocutaneous Leishmaniasis, American
New World Cutaneous Leishmaniasis	Leishmaniasis, Mucocutaneous
Espundia	Leishmania Braziliensis Infection

Splenic Disease

Splenic Diseases	Dyssplenism
Spleen Disease	Abnormality Of The Spleen
Spleen Diseases

Visceral Leishmaniasis

Kala-Azar	Leishmaniasis, Visceral
Infection By Visceral Leishmaniasis	Leishmaniasis Visceral
Sahib Disease	Ponos
Burdwan Fever	Mard El Bicha
Sirkari Disease	Indian Visceral Leishmaniasis
Dumdum Fever	Visceral Leishmaniasis Due To Leishmania Donovani

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11520	RAB11FIP5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	RAB11FIP5	VGNC	VGNC:64471
Bos taurus	RAB11FIP5	VGNC	VGNC:54474
Canis familiaris	RAB11FIP5	VGNC	VGNC:45252
Mus musculus	RAB11FIP5	MGD	MGI:1098586
Rattus norvegicus	RAB11FIP5	RGD	RGD:1592069
Macaca mulatta	RAB11FIP5	VGNC	VGNC:106203

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