GGN - gametogenetin Gene

Homo sapiens

Gene ID: 199720 | Gene type: protein coding

About GGN

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:38,384,267-38,388,384 (from NCBI)

This gene has 5 transcripts (splice variants), 77 orthologues, 2 paralogues and is associated with 1 phenotype. Restricted expression toward testis (RPKM 12.5).

Summary

This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis. [provided by RefSeq, Jul 2008]

GGN Products(1)

mRNA	Protein	Name
NM_152657.4	NP_689870.3	gametogenetin

Protein Preferred Names

Protein Names

gametogenetin

Related Diseases

Diseases

Alias

Spermatogenic Failure 69

SPGF69

Spermatogenic Failure 9

Male Infertility Due To Globozoospermia	SPGF9
Male Infertility Due To Round-Headed Spermatozoa	Globozoospermia, Complete
Globozoospermia, Total	Globozoospermia
Globozoospermia Syndrome	Round-Headed Sperm Syndrome
Globozoospermia Complete	Globozoospermia Total

Chromosome 17q12 Deletion Syndrome

17q12 Microdeletion Syndrome	Del(17)(Q12)
Monosomy 17q12

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05400	GGN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	GGN	RGD	RGD:1306765
Bos taurus	GGN	VGNC	VGNC:29341
Mus musculus	GGN	MGD	MGI:2181461
Macaca mulatta	GGN	VGNC	VGNC:72740
Canis familiaris	GGN	VGNC	VGNC:41199
Others	GGN	NCBI