ARHGAP45 - Rho GTPase activating protein 45 Gene

Homo sapiens

Also known as HA-1; HMHA1; HLA-HA1

Gene ID: 23526 | Gene type: protein coding

About ARHGAP45

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:1,065,959-1,086,628 (from NCBI)

This gene has 16 transcripts (splice variants), 214 orthologues and 2 paralogues. Broad expression in spleen (RPKM 23.6), bone marrow (RPKM 17.0) and 22 other tissues.

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in activation of GTPase activity. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

ARHGAP45 Products(5)

mRNA	Protein	Name
NM_001258328.4	NP_001245257.1	rho GTPase-activating protein 45 isoform 2 precursor
NM_001282334.2	NP_001269263.1	rho GTPase-activating protein 45 isoform 3
NM_001282335.3	NP_001269264.1	rho GTPase-activating protein 45 isoform 4
NM_001321232.2	NP_001308161.1	rho GTPase-activating protein 45 isoform 5
NM_012292.5	NP_036424.2	rho GTPase-activating protein 45 isoform 1 precursor

ARHGAP45 Protein Structure

RhoGAP

0
200
400
600
800
1000
1136 a.a.

Protein Preferred Names

Protein Names

rho GTPase-activating protein 45

histocompatibility (minor) HA-1

Related Diseases

Diseases

Alias

Graft-Versus-Host Disease

Graft-Versus-Host Disease, Susceptibility To	Graft Versus Host Disease
GVHDS	Graft-Versus-Host Disease, Protection Against
Gvh	Graft-Vs-Host Disease
Gvhd - [Graft-Versus-Host Disease]	Graft-Versus-Host Reaction Or Disease
Gvh - [Graft-Versus-Host] Disease	Gvh - [Graft-Versus-Host] Reaction

Acute Graft Versus Host Disease

Acute Graft-Versus-Host Disease	Acute Gvhd
Acute Gvh Disease	Acute Gvhd - [Graft-Versus-Host Disease]

Leukemia

Leukemias	Leukaemia, Unspecified, Without Mention Of Remission
Aleukemic Leukaemia	Chronic Leukaemia
Subacute Leukaemia	Leukaemia Disorder
Leukaemia Nos

Hematologic Cancer

Hematologic Neoplasm	Hematologic Neoplasms
Hematologic Malignancies	Blood Cancer
Hematologic Malignancy	Hematological Tumors
Hematopoietic And Lymphoid System Tumor	Hematopoietic Cancer
Hematopoietic Neoplasm	Hematopoietic Tumors
Malignant Hematopoietic Neoplasm	Liquid Tumor
Hematopoietic Neoplasms

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00938	ARHGAP45 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	ARHGAP45	VGNC	VGNC:59894
Macaca mulatta	ARHGAP45	VGNC	VGNC:69847
Canis familiaris	ARHGAP45	VGNC	VGNC:38066
Rattus norvegicus	ARHGAP45	RGD	RGD:1308662
Bos taurus	ARHGAP45	VGNC	VGNC:59319
Mus musculus	ARHGAP45	MGD	MGI:1917969

Name
Email *

	Sorry, but the email address you supplied was invalid.