CCDC116 - coiled-coil domain containing 116 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 164592

Summary

Located in centrosome. Implicated in Lung Cancer. [provided by Alliance of Genome Resources, Jul 2025]
Restricted expression toward testis (RPKM 8.7).

CCDC116 Products (2)

mRNA Protein Name
NM_001331066.2 NP_001317995.1 coiled-coil domain-containing protein 116 isoform 2
NM_152612.3 NP_689825.2 coiled-coil domain-containing protein 116 isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
25074808 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCDC116 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CCDC116 Q8IYX3 KRT40 Homo sapiens Q6A162
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 KRT40 Homo sapiens Q6A162
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 FAM9B Homo sapiens Q8IZU0
Y2H Array
25416956
Intra
CCDC116 Q8IYX3 FAM9B Homo sapiens Q8IZU0
Y2H Prey Pooling
25416956
Intra
CCDC116 Q8IYX3 MTUS2 Homo sapiens Q5JR59-3
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 MTUS2 Homo sapiens Q5JR59-3
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 AKAP9 Homo sapiens Q6PJH3
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 AKAP9 Homo sapiens Q6PJH3
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 CTAG1A Homo sapiens P78358
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 CTAG1A Homo sapiens P78358
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 ZMYND12 Homo sapiens Q9H0C1
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 ZMYND12 Homo sapiens Q9H0C1
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 ZMYND12 Homo sapiens Q9H0C1
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 MEIS3 Homo sapiens Q99687-3
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 MEIS3 Homo sapiens Q99687-3
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 MEIS3 Homo sapiens Q99687-3
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 PKNOX2 Homo sapiens Q96KN3
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 PKNOX2 Homo sapiens Q96KN3
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 PKNOX2 Homo sapiens Q96KN3
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 CEP20 Homo sapiens Q96NB1
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 CEP20 Homo sapiens Q96NB1
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 CEP20 Homo sapiens Q96NB1
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 TRAF1 Homo sapiens Q13077
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 TRAF1 Homo sapiens Q13077
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 TRAF1 Homo sapiens Q13077
Y2H Prey Pooling
25416956
Intra
CCDC116 Q8IYX3 CARD10 Homo sapiens Q9BWT7
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 CARD10 Homo sapiens Q9BWT7
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 CARD10 Homo sapiens Q9BWT7
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 COG6 Homo sapiens Q9Y2V7
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 COG6 Homo sapiens Q9Y2V7
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 COG6 Homo sapiens Q9Y2V7
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 CDCA7L Homo sapiens Q96GN5
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 GOLGA6L9 Homo sapiens A6NEM1
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 GOLGA6L9 Homo sapiens A6NEM1
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 ZNF655 Homo sapiens Q8N720
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 ZNF655 Homo sapiens Q8N720
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 ZNF655 Homo sapiens Q8N720
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 PPP1R16A Homo sapiens Q96I34
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 PPP1R16A Homo sapiens Q96I34
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 PPP1R16A Homo sapiens Q96I34
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 HSF2BP Homo sapiens O75031
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 HSF2BP Homo sapiens O75031
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 HSF2BP Homo sapiens O75031
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 MDFI Homo sapiens Q99750
Y2H Prey Pooling
25416956
Intra
CCDC116 Q8IYX3 MDFI Homo sapiens Q99750
Y2H Array
25416956
Intra
CCDC116 Q8IYX3 MDFI Homo sapiens Q99750
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 MDFI Homo sapiens Q99750
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 MDFI Homo sapiens Q99750
Validated Y2H
25416956
Intra
CCDC116 Q8IYX3 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
25416956
Intra
CCDC116 Q8IYX3 USHBP1 Homo sapiens Q8N6Y0
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 USHBP1 Homo sapiens Q8N6Y0
Validated Y2H
32296183
Intra
CCDC116 Q8IYX3 USHBP1 Homo sapiens Q8N6Y0
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 USHBP1 Homo sapiens Q8N6Y0
Y2H Prey Pooling
25416956
Intra
CCDC116 Q8IYX3 BEX3 Homo sapiens Q00994
Y2H
21516116
Intra
CCDC116 Q8IYX3 BEX3 Homo sapiens Q00994
Y2H Prey Pooling
25416956
Intra
CCDC116 Q8IYX3 BEX3 Homo sapiens Q00994
Y2H Array
25416956
Intra
CCDC116 Q8IYX3 TADA2A Homo sapiens O75478
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 TADA2A Homo sapiens O75478
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 MTUS2 Homo sapiens Q5JR59
Y2H
21516116
Intra
CCDC116 Q8IYX3 IGFBP6 Homo sapiens P24592
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 IGFBP6 Homo sapiens P24592
Y2H Array
32296183
Intra
CCDC116 Q8IYX3 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
Intra
CCDC116 Q8IYX3 KRT31 Homo sapiens Q15323
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02025 CCDC115 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02033 CCDC146 Human Pre-designed siRNA Set A Pre-designed Set / Unkown