CCNB1IP1 - cyclin B1 interacting protein 1 Gene

Also Known as HEI10; C14orf18

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57820

About CCNB1IP1

Cytogenetic location: 14q11.2 Genomic coordinates (GRCh38): 14:20,311,370-20,333,279 (from NCBI)

This gene has 16 transcripts (splice variants), 198 orthologues and is associated with 50 phenotypes. Ubiquitous expression in ovary (RPKM 41.4), thyroid (RPKM 28.8) and 24 other tissues.

Summary

HEI10 is a member of the E3 ubiquitin Ligase family and functions in progression of the cell cycle through G(2)/M.[supplied by OMIM, Apr 2004]

CCNB1IP1 Products (3)

mRNA Protein Name
NM_021178.5 NP_067001.3 E3 ubiquitin-protein ligase CCNB1IP1
NM_182849.3 NP_878269.1 E3 ubiquitin-protein ligase CCNB1IP1
NM_182852.4 NP_878272.1 E3 ubiquitin-protein ligase CCNB1IP1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
12612082 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CCNB1IP1 Protein Structure

zf-RING_5

zf-RING_5: zinc-RING finger domain (10 - 52)

  • 0
  • 100
  • 200
  • 277 a.a.
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase CCNB1IP1

  • RING-type E3 ubiquitin transferase CCNB1IP1

CCNB1IP1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CCNB1IP1 Q9NPC3 H1-3 Homo sapiens P16402
Anti Tag CoIP
28514442
Intra
CCNB1IP1 Q9NPC3 H1-3 Homo sapiens P16402
Anti Tag CoIP
33961781
Intra
CCNB1IP1 Q9NPC3 PRKAA2 Homo sapiens P54646
Y2H Prey Pooling
25416956
Intra
CCNB1IP1 Q9NPC3 PRKAA2 Homo sapiens P54646
Y2H Array
25416956
Intra
CCNB1IP1 Q9NPC3 EPM2AIP1 Homo sapiens Q7L775
Validated Y2H
25416956
Intra
CCNB1IP1 Q9NPC3 EPM2AIP1 Homo sapiens Q7L775
Y2H Array
25416956
Intra
CCNB1IP1 Q9NPC3 KRT15 Homo sapiens P19012
Y2H Array
25416956
Intra
CCNB1IP1 Q9NPC3 CCNB1IP1 Homo sapiens Q9NPC3
Y2H Array
31515488
Intra
CCNB1IP1 Q9NPC3 CCNB1IP1 Homo sapiens Q9NPC3
Y2H Pooling
16189514
Intra
CCNB1IP1 Q9NPC3 KEAP1 Homo sapiens Q14145
Y2H Array
25416956
Intra
CCNB1IP1 Q9NPC3 CCNB1IP1 Homo sapiens Q9NPC3
Y2H Array
25416956
Intra
CCNB1IP1 Q9NPC3 KEAP1 Homo sapiens Q14145
Validated Y2H
25416956
Intra
CCNB1IP1 Q9NPC3 KEAP1 Homo sapiens Q14145
Y2H Prey Pooling
25416956
Cross
CCNB1IP1 Q9NPC3 ubiqp_xenla Crosspus laevis P62972
Pull Down
12612082
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02119 CCNB1IP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta CCNB1IP1 VGNC VGNC:70827
Bos taurus CCNB1IP1 VGNC VGNC:26959
Canis familiaris CCNB1IP1 VGNC VGNC:38894
Felis catus CCNB1IP1 VGNC VGNC:60552
Rattus norvegicus CCNB1IP1 RGD RGD:1561930
Mus musculus CCNB1IP1 MGD MGI:2685134
Others CCNB1IP1 NCBI