ZBTB10 - zinc finger and BTB domain containing 10 Gene

Also Known as RINZF

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 65986

About ZBTB10

Cytogenetic location: 8q21.13 Genomic coordinates (GRCh38): 8:80,485,593-80,526,265 (from NCBI)

This gene has 5 transcripts (splice variants), 206 orthologues and 5 paralogues. Ubiquitous expression in prostate (RPKM 6.2), placenta (RPKM 5.4) and 25 other tissues.

Summary

Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ZBTB10 Products (3)

mRNA Protein Name
NM_001105539.3 NP_001099009.1 zinc finger and BTB domain-containing protein 10 isoform a
NM_001277145.2 NP_001264074.1 zinc finger and BTB domain-containing protein 10 isoform c
NM_023929.5 NP_076418.3 zinc finger and BTB domain-containing protein 10 isoform b

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables telomeric DNA binding IDA
IDA: Inferred from direct assay
30629181 GOA
Cellular Component GO Annotation Evidence References Source
located in chromosome, telomeric region IDA
IDA: Inferred from direct assay
30629181 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZBTB10 Protein Structure

BTB

BTB: BTB/POZ domain (354 - 461)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (737 - 761)

  • 0
  • 200
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  • 600
  • 800
  • 871 a.a.
Protein Preferred Names Protein Names

zinc finger and BTB domain-containing protein 10

  • zinc finger protein RIN ZF

ZBTB10 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZBTB10 Q96DT7 LSM4 Homo sapiens Q9Y4Z0
Y2H Prey Pooling
25416956
Intra
ZBTB10 Q96DT7 MORF4L1 Homo sapiens Q9UBU8
Validated Y2H
25416956
Intra
ZBTB10 Q96DT7 MORF4L2 Homo sapiens Q15014
Y2H Array
25416956
Intra
ZBTB10 Q96DT7 ZNF417 Homo sapiens Q8TAU3
Y2H Array
25416956
Intra
ZBTB10 Q96DT7 MOB3C Homo sapiens Q70IA8
Y2H Array
29892012
Intra
ZBTB10 Q96DT7 MOB3C Homo sapiens Q70IA8
Y2H Prey Pooling
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15960 ZBTB10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ZBTB10 MGD MGI:2139883
Rattus norvegicus ZBTB10 RGD RGD:708377
Macaca mulatta ZBTB10 VGNC VGNC:79904
Bos taurus ZBTB10 VGNC VGNC:37058
Canis familiaris ZBTB10 VGNC VGNC:48520
Others ZBTB10 NCBI