VASN - vasorin Gene

Homo sapiens

Also known as SLITL2

Gene ID: 114990 | Gene type: protein coding

About VASN

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:4,371,848-4,383,538 (from NCBI)

This gene has 1 transcript (splice variant), 1 gene allele, 255 orthologues and 22 paralogues. Broad expression in placenta (RPKM 16.9), kidney (RPKM 16.4) and 24 other tissues.

Summary

Enables transforming growth factor beta binding activity. Involved in negative regulation of epithelial to mesenchymal transition and negative regulation of transforming growth factor beta receptor signaling pathway. Located in cell surface and extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

VASN Products(1)

mRNA	Protein	Name
NM_138440.3	NP_612449.2	vasorin precursor

VASN Protein Structure

LRRNT

LRR_1

LRR_8

0
200
400
600
673 a.a.

Protein Preferred Names

Protein Names

vasorin

protein slit-like 2

Recombinant VASN Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70999	Vasorin Protein, Human (552a.a, HEK293, His)	AAH68575.1 (C24-P575)	≥95%
HY-P74477	Vasorin Protein, Human (575a.a, HEK293, His)	Q6EMK4 (M1-P575)	≥95%

Related Diseases

Diseases

Alias

Hematuria, Benign Familial

Benign Familial Hematuria	BFH
Thin Membrane Nephropathy	Tmn
Thin Basement Membrane Nephropathy	Thin-Basement-Membrane Nephropathy
Hematuria, Familial Benign	Hematuria Benign Familial
Hematuria, Benign, Familial	Thin Basement Membrane Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15608	VASN Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	VASN	MGD	MGI:2177651
Canis familiaris	VASN	VGNC	VGNC:54089
Rattus norvegicus	VASN	RGD	RGD:1598149
Felis catus	VASN	VGNC	VGNC:66921
Others	VASN	NCBI