LCE2D - late cornified envelope 2D Gene
Also Known as LEP12; SPRL1A
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 353141
Summary
Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Jul 2025]
Restricted expression toward skin (RPKM 31.0).
LCE2D Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_178430.4 | NP_848517.1 | late cornified envelope protein 2D |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25416956 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service
LCE2D Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
LCE2D | Q5TA82 | KRTAP10-8 | Homo sapiens | P60410 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP10-8 | Homo sapiens | P60410 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP10-8 | Homo sapiens | P60410 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP10-9 | Homo sapiens | P60411 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP10-9 | Homo sapiens | P60411 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP10-9 | Homo sapiens | P60411 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP10-9 | Homo sapiens | P60411 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP10-5 | Homo sapiens | P60370 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | ADAMTSL4 | Homo sapiens | Q6UY14-3 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | SUMO1P1 | Homo sapiens | G2XKQ0 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | SUMO1P1 | Homo sapiens | G2XKQ0 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | SUMO1P1 | Homo sapiens | G2XKQ0 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | LCE1B | Homo sapiens | Q5T7P3 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | LCE1B | Homo sapiens | Q5T7P3 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | VASN | Homo sapiens | Q6EMK4 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-6 | Homo sapiens | Q6L8G9 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-6 | Homo sapiens | Q6L8G9 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-6 | Homo sapiens | Q6L8G9 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | SLC39A7 | Homo sapiens | Q92504 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | RGS20 | Homo sapiens | O76081 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP1-5 | Homo sapiens | Q9BYS1 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP1-5 | Homo sapiens | Q9BYS1 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP1-5 | Homo sapiens | Q9BYS1 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | LCE1D | Homo sapiens | Q5T752 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | LCE1D | Homo sapiens | Q5T752 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP1-3 | Homo sapiens | Q8IUG1 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP1-3 | Homo sapiens | Q8IUG1 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP12-3 | Homo sapiens | P60328 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP12-3 | Homo sapiens | P60328 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | VWC2 | Homo sapiens | Q2TAL6 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | VWC2 | Homo sapiens | Q2TAL6 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | LCE1F | Homo sapiens | Q5T754 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | LCE1F | Homo sapiens | Q5T754 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-2 | Homo sapiens | Q701N4 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-2 | Homo sapiens | Q701N4 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-2 | Homo sapiens | Q701N4 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP9-8 | Homo sapiens | Q9BYQ0 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP9-8 | Homo sapiens | Q9BYQ0 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP9-8 | Homo sapiens | Q9BYQ0 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP1-1 | Homo sapiens | Q07627 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP1-1 | Homo sapiens | Q07627 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | LCE1A | Homo sapiens | Q5T7P2 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | LCE1A | Homo sapiens | Q5T7P2 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP6-2 | Homo sapiens | Q3LI66 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP6-2 | Homo sapiens | Q3LI66 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | LCE2C | Homo sapiens | Q5TA81 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | LCE2C | Homo sapiens | Q5TA81 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | GUCD1 | Homo sapiens | Q96NT3-2 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-7 | Homo sapiens | Q6L8G8 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-7 | Homo sapiens | Q6L8G8 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-7 | Homo sapiens | Q6L8G8 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP17-1 | Homo sapiens | Q9BYP8 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP17-1 | Homo sapiens | Q9BYP8 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP17-1 | Homo sapiens | Q9BYP8 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP10-6 | Homo sapiens | P60371 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP10-6 | Homo sapiens | P60371 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | NUFIP2 | Homo sapiens | Q7Z417 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP19-2 | Homo sapiens | Q3LHN2 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP19-2 | Homo sapiens | Q3LHN2 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | LCE1C | Homo sapiens | Q5T751 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | NR4A3 | Homo sapiens | Q92570 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | NR4A3 | Homo sapiens | Q92570 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | NR4A3 | Homo sapiens | Q92570 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP2-4 | Homo sapiens | Q9BYR9 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP2-4 | Homo sapiens | Q9BYR9 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP2-4 | Homo sapiens | Q9BYR9 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | NOTCH2NLC | Homo sapiens | P0DPK4 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | NOTCH2NLC | Homo sapiens | P0DPK4 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | RNF4 | Homo sapiens | P78317 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | RNF4 | Homo sapiens | P78317 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-1 | Homo sapiens | Q9BYQ7 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-1 | Homo sapiens | Q9BYQ7 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | GLRX3 | Homo sapiens | O76003 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | GLRX3 | Homo sapiens | O76003 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | GLRX3 | Homo sapiens | O76003 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | GLRX3 | Homo sapiens | O76003 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | SPRY1 | Homo sapiens | O43609 | 31515488 | |
|
Intra
|
LCE2D | Q5TA82 | SPRY1 | Homo sapiens | O43609 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | SPRY1 | Homo sapiens | O43609 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | SPRY1 | Homo sapiens | O43609 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | SPRY1 | Homo sapiens | O43609 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | CYSRT1 | Homo sapiens | A8MQ03 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | CYSRT1 | Homo sapiens | A8MQ03 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-9 | Homo sapiens | P26371 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP5-9 | Homo sapiens | P26371 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | P4HB | Homo sapiens | P07237 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | P4HB | Homo sapiens | P07237 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | TRIM42 | Homo sapiens | Q8IWZ5 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | TRIM42 | Homo sapiens | Q8IWZ5 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | TRIM42 | Homo sapiens | Q8IWZ5 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | PLA2G10 | Homo sapiens | O15496 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | PLA2G10 | Homo sapiens | O15496 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | PLSCR1 | Homo sapiens | O15162 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | PLSCR1 | Homo sapiens | O15162 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | OTX1 | Homo sapiens | P32242 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | OTX1 | Homo sapiens | P32242 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | OTX1 | Homo sapiens | P32242 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | HOXA1 | Homo sapiens | P49639 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | HOXA1 | Homo sapiens | P49639 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | EFEMP2 | Homo sapiens | O95967 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | EFEMP2 | Homo sapiens | O95967 | 25416956 | |
|
Intra
|
LCE2D | Q5TA82 | SMCP | Homo sapiens | P49901 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | SMCP | Homo sapiens | P49901 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | TSPAN4 | Homo sapiens | O14817 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | TSPAN4 | Homo sapiens | O14817 | 32296183 | |
|
Intra
|
LCE2D | Q5TA82 | NOTCH2NLA | Homo sapiens | Q7Z3S9 | 25416956 |
Cross: Cross-species interaction
Intra: Intraspecies interaction