LCE1D - late cornified envelope 1D Gene
Also Known as LEP4
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 353134
Summary
Enables identical protein binding activity. Involved in cognition. Acts upstream of or within cellular response to calcium ion. Located in cornified envelope and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Restricted expression toward skin (RPKM 30.0).
LCE1D Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_178352.3 | NP_848129.1 | late cornified envelope protein 1D |
| Molecular Function GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| enables identical protein binding |
IPI
IPI: Inferred from physical interaction
|
32296183 | GOA |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
27107012 | GOA |
| Biological Process GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| acts upstream of or within cellular response to calcium ion |
IDA
IDA: Inferred from direct assay
|
11698679 | GOA |
| involved in cognition |
IMP
IMP: Inferred from mutant phenotype
|
23227193 | GOA |
| Cellular Component GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| located in cornified envelope |
IDA
IDA: Inferred from direct assay
|
11698679 | GOA |
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
11698679 | GOA |
| located in perinuclear region of cytoplasm |
IDA
IDA: Inferred from direct assay
|
11698679 | GOA |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
LCE1D Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Verweise |
|---|---|---|---|---|---|---|---|
|
Intra
|
LCE1D | Q5T752 | KRTAP10-8 | Homo sapiens | P60410 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP10-8 | Homo sapiens | P60410 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP10-9 | Homo sapiens | P60411 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP10-9 | Homo sapiens | P60411 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP10-7 | Homo sapiens | P60409 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP10-7 | Homo sapiens | P60409 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-2 | Homo sapiens | Q9BYR5 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | UBE2I | Homo sapiens | Q7KZS0 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | UBE2I | Homo sapiens | Q7KZS0 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | UBE2I | Homo sapiens | Q7KZS0 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE1B | Homo sapiens | Q5T7P3 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE2A | Homo sapiens | Q5TA79 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE2A | Homo sapiens | Q5TA79 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE2A | Homo sapiens | Q5TA79 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE2D | Homo sapiens | Q5TA82 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-6 | Homo sapiens | Q6L8G9 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-6 | Homo sapiens | Q6L8G9 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-6 | Homo sapiens | Q6L8G9 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-11 | Homo sapiens | Q9BYQ6 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP9-3 | Homo sapiens | Q9BYQ3 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP9-2 | Homo sapiens | Q9BYQ4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP9-2 | Homo sapiens | Q9BYQ4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP9-2 | Homo sapiens | Q9BYQ4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE2B | Homo sapiens | O14633 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE2B | Homo sapiens | O14633 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP1-5 | Homo sapiens | Q9BYS1 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP1-5 | Homo sapiens | Q9BYS1 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP1-5 | Homo sapiens | Q9BYS1 | 27107012 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP1-5 | Homo sapiens | Q9BYS1 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | CYSRT1 | Homo sapiens | A8MQ03 | 27107012 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-11 | Homo sapiens | Q6L8G4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | CYSRT1 | Homo sapiens | A8MQ03 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-11 | Homo sapiens | Q6L8G4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-11 | Homo sapiens | Q6L8G4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-11 | Homo sapiens | Q6L8G4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | CYSRT1 | Homo sapiens | A8MQ03 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP1-3 | Homo sapiens | Q8IUG1 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP1-3 | Homo sapiens | Q8IUG1 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE1E | Homo sapiens | Q5T753 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE1E | Homo sapiens | Q5T753 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE1E | Homo sapiens | Q5T753 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | PCSK5 | Homo sapiens | Q92824-2 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | PCSK5 | Homo sapiens | Q92824-2 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | PCSK5 | Homo sapiens | Q92824-2 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE1F | Homo sapiens | Q5T754 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-4 | Homo sapiens | Q9BYR3 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-2 | Homo sapiens | Q701N4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP9-8 | Homo sapiens | Q9BYQ0 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-4 | Homo sapiens | Q6L8H1 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE2C | Homo sapiens | Q5TA81 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE2C | Homo sapiens | Q5TA81 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE2C | Homo sapiens | Q5TA81 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-3 | Homo sapiens | Q6L8H2 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE3B | Homo sapiens | Q5TA77 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE3B | Homo sapiens | Q5TA77 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE3B | Homo sapiens | Q5TA77 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-5 | Homo sapiens | Q9BYR2 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE1C | Homo sapiens | Q5T751 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | LCE1C | Homo sapiens | Q5T751 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP2-4 | Homo sapiens | Q9BYR9 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP2-4 | Homo sapiens | Q9BYR9 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP2-4 | Homo sapiens | Q9BYR9 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | MEOX2 | Homo sapiens | Q6FHY5 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | MEOX2 | Homo sapiens | Q6FHY5 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | MEOX2 | Homo sapiens | Q6FHY5 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | NOTCH2NLC | Homo sapiens | P0DPK4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | NOTCH2NLC | Homo sapiens | P0DPK4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | RNF4 | Homo sapiens | P78317 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | RNF4 | Homo sapiens | P78317 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | MACO1 | Homo sapiens | Q8N5G2 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-1 | Homo sapiens | Q9BYQ7 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-1 | Homo sapiens | Q9BYQ7 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | RGS17 | Homo sapiens | Q9UGC6 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | RGS17 | Homo sapiens | Q9UGC6 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | RGS17 | Homo sapiens | Q9UGC6 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-9 | Homo sapiens | P26371 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP5-9 | Homo sapiens | P26371 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | PIAS4 | Homo sapiens | Q8N2W9 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | PIAS4 | Homo sapiens | Q8N2W9 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | PIAS4 | Homo sapiens | Q8N2W9 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | TRIM42 | Homo sapiens | Q8IWZ5 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | MDFI | Homo sapiens | Q99750 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | KRTAP4-12 | Homo sapiens | Q9BQ66 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | HOXA1 | Homo sapiens | P49639 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | HOXA1 | Homo sapiens | P49639 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | NTAQ1 | Homo sapiens | Q96HA8 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | CATSPER1 | Homo sapiens | Q8NEC5 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | SMCP | Homo sapiens | P49901 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | SMCP | Homo sapiens | P49901 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | RAD54L2 | Homo sapiens | Q9Y4B4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | RAD54L2 | Homo sapiens | Q9Y4B4 | 32296183 | |
|
Intra
|
LCE1D | Q5T752 | RAD54L2 | Homo sapiens | Q9Y4B4 | 32296183 |
Cross: Cross-species interaction
Intra: Intraspecies interaction
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