LCE1C - late cornified envelope 1C Gene

Also Known as LEP3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 353133

Summary

Predicted to be involved in keratinization. [provided by Alliance of Genome Resources, Jul 2025]
Restricted expression toward skin (RPKM 108.0).

LCE1C Products (2)

mRNA Protein Name
NM_001276331.2 NP_001263260.1 late cornified envelope protein 1C isoform 2
NM_178351.4 NP_848128.1 late cornified envelope protein 1C isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LCE1C Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
LCE1C Q5T751 KRTAP4-2 Homo sapiens Q9BYR5
Validated Y2H
32296183
Intra
LCE1C Q5T751 ADAMTSL4 Homo sapiens Q6UY14-3
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE1B Homo sapiens Q5T7P3
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE4A Homo sapiens Q5TA78
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE2A Homo sapiens Q5TA79
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE2D Homo sapiens Q5TA82
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE2D Homo sapiens Q5TA82
Y2H Array
32296183
Intra
LCE1C Q5T751 VASN Homo sapiens Q6EMK4
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP5-6 Homo sapiens Q6L8G9
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP4-11 Homo sapiens Q9BYQ6
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP9-3 Homo sapiens Q9BYQ3
Validated Y2H
32296183
Intra
LCE1C Q5T751 SLC39A7 Homo sapiens Q92504
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE1D Homo sapiens Q5T752
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE5A Homo sapiens Q5TCM9
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE1F Homo sapiens Q5T754
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP4-4 Homo sapiens Q9BYR3
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP5-2 Homo sapiens Q701N4
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP9-8 Homo sapiens Q9BYQ0
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE1A Homo sapiens Q5T7P2
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP5-4 Homo sapiens Q6L8H1
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE2C Homo sapiens Q5TA81
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP5-3 Homo sapiens Q6L8H2
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE3B Homo sapiens Q5TA77
Validated Y2H
32296183
Intra
LCE1C Q5T751 GUCD1 Homo sapiens Q96NT3-2
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP4-5 Homo sapiens Q9BYR2
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP5-11 Homo sapiens Q6L8G4
Validated Y2H
32296183
Intra
LCE1C Q5T751 MACO1 Homo sapiens Q8N5G2
Validated Y2H
32296183
Intra
LCE1C Q5T751 TRIM42 Homo sapiens Q8IWZ5
Validated Y2H
32296183
Intra
LCE1C Q5T751 NECTIN2 Homo sapiens Q92692-2
Validated Y2H
32296183
Intra
LCE1C Q5T751 SPRED2 Homo sapiens Q7Z698
Validated Y2H
32296183
Intra
LCE1C Q5T751 CRCT1 Homo sapiens Q9UGL9
Validated Y2H
32296183
Intra
LCE1C Q5T751 KRTAP4-12 Homo sapiens Q9BQ66
Validated Y2H
32296183
Intra
LCE1C Q5T751 NTAQ1 Homo sapiens Q96HA8
Validated Y2H
32296183
Intra
LCE1C Q5T751 CHIC2 Homo sapiens Q9UKJ5
Validated Y2H
32296183
Intra
LCE1C Q5T751 NTN4 Homo sapiens Q9HB63
Validated Y2H
32296183
Intra
LCE1C Q5T751 q96ej4_human Homo sapiens Q96EJ4
Validated Y2H
32296183
Intra
LCE1C Q5T751 PLSCR3 Homo sapiens Q9NRY6
Validated Y2H
32296183
Intra
LCE1C Q5T751 PLSCR4 Homo sapiens Q9NRQ2
Validated Y2H
32296183
Intra
LCE1C Q5T751 q7z783_human Homo sapiens Q7Z783
Validated Y2H
32296183
Intra
LCE1C Q5T751 LCE3A Homo sapiens Q5TA76
Validated Y2H
32296183
Intra
LCE1C Q5T751 CHRD Homo sapiens Q9H2X0
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-D3009 LCE1 / Unkown