SMCP - sperm mitochondria associated cysteine rich protein Gene

Homo sapiens

Also known as MCS; MCSP; HSMCSGEN1

Gene ID: 4184 | Gene type: protein coding

About SMCP

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:152,878,322-152,885,047 (from NCBI)

This gene has 1 transcript (splice variant) and 29 orthologues. Restricted expression toward testis (RPKM 221.5).

Summary

Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by this gene localizes to the capsule associated with the mitochondrial outer membranes and is thought to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath. [provided by RefSeq, Jul 2008]

SMCP Products(1)

mRNA	Protein	Name
NM_030663.3	NP_109588.2	sperm mitochondrial-associated cysteine-rich protein

Protein Preferred Names

Protein Names

sperm mitochondrial-associated cysteine-rich protein

testicular tissue protein Li 119

Related Diseases

Diseases

Alias

Spermatogenic Failure 21

SPGF21

Male Infertility

Infertility, Male	Infertility Male
Male Sterility	Absolute Infertility

Corneal Dystrophy, Subepithelial Mucinous

Subepithelial Mucinous Corneal Dystrophy

SMCD

Infertility

Male Infertility Due To Acephalic Spermatozoa

Acephalic Spermatozoa Syndrome

Spermatogenic Failure

Azoospermia	Spgf
Spermatogenic Failure, Susceptibility To	Absent Sperm
Aspermatogenesis	Infertility Due To Azoospermia
Hypospermatogenesis	Azoospermatism

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13427	SMCP Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	SMCP	RGD	RGD:3069
Canis familiaris	SMCP	VGNC	VGNC:46552
Mus musculus	SMCP	MGD	MGI:96945
Macaca mulatta	SMCP	VGNC	VGNC:77816
Bos taurus	SMCP	VGNC	VGNC:59191