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116729

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By Targets:	11β-HSD (1) Antibiotic (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-100151

RGH-5526 GYKI-11679	Others	Cardiovascular Disease
RGH-5526 (GYKI-11679) is a new antihypertensive agent.

HY-113700

PD 116779	Antibiotic	Cancer
PD 116779 is an Antibiotic with anticancer activity. PD 116779 demonstrates moderate cytotoxicity against L1210 lymphocytic leukemia and HCT-8 human colon adenocarcinoma cell lines with IC₅₀ values of 3.55x10 ^-7 and 4.08x10 ^-7 M, respectively .

HY-118113

BVT-116429	11β-HSD	Others
BVT-116429 is an 11βHSD1 inhibitor with the activity of increasing adiponectin concentration and improving glucose homeostasis in diabetic mice. BVT-116429 can increase plasma adiponectin levels in diabetic KKAy mice, reduce basal insulin levels, and reduce fasting blood glucose levels after 10 days of inhibition, similar to the effect of rosiglitazone.

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HY-P78760

	IL-13 Protein, Canine (HEK293, His) IL13; ALRH; BHR1; MGC116786; MGC116788; MGC116789; P600; Interleukin-13	Canine	HEK293
	IL-13 is a cytokine. IL-13 down-regulates proinflammatory cytokine synthesis by partially inhibiting NF-kappa-B. IL-13 induces vascular cell adhesion protein 1/VCAM1 to exert its biological role through its receptor, activating JAK1 and TYK2, thereby activating STAT6. IL-13 Protein, Canine (HEK293, His) is the recombinant canine-derived IL-13 protein, expressed by HEK293 , with C-His labeled tag.

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HY-P81504

	Parvalbumin Antibody (YA1249) D22S749 antibody; MGC116759 antibody; Parvalbumin alpha antibody; PRVA_HUMAN antibody; PVALB antibody	WB, IHC-P, IP	Human
	Parvalbumin Antibody (YA1249) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Parvalbumin.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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