MT1M - metallothionein 1M Gene

Also Known as MT1; MT1K; MT-1M; MT-IM

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4499

About MT1M

Cytogenetic location: 16q13 Genomic coordinates (GRCh38): 16:56,632,659-56,633,981 (from NCBI)

This gene has 2 transcripts (splice variants), 207 orthologues and 11 paralogues. Broad expression in colon (RPKM 54.9), small intestine (RPKM 40.3) and 14 other tissues.

Summary

This gene encodes a member of the metallothionein superfamily, type 1 family. Metallothioneins have a high content of cysteine residues that bind various heavy metals. These genes are transcriptionally regulated by both heavy metals and glucocorticoids. [provided by RefSeq, Oct 2011]

MT1M Products (1)

mRNA Protein Name
NM_176870.3 NP_789846.2 metallothionein-1M

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MT1M Protein Structure

Metallothio

Metallothio: Metallothionein (1 - 61)

  • 0
  • 61 a.a.
Protein Preferred Names Protein Names

metallothionein-1M

  • metallothionein 1K

MT1M Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
MT1M Q8N339 KRTAP17-1 Homo sapiens Q9BYP8
Validated Y2H
32296183
Intra
MT1M Q8N339 KRTAP17-1 Homo sapiens Q9BYP8
Y2H Array
32296183
Intra
MT1M Q8N339 KRTAP17-1 Homo sapiens Q9BYP8
Y2H Prey Pooling
32296183
Intra
MT1M Q8N339 KRTAP5-1 Homo sapiens Q6L8H4
Y2H Array
32296183
Intra
MT1M Q8N339 KRTAP5-1 Homo sapiens Q6L8H4
Y2H Prey Pooling
32296183
Intra
MT1M Q8N339 CYSRT1 Homo sapiens A8MQ03
Y2H Prey Pooling
32296183
Intra
MT1M Q8N339 CYSRT1 Homo sapiens A8MQ03
Y2H Array
32296183
Intra
MT1M Q8N339 KRTAP5-9 Homo sapiens P26371
Y2H Prey Pooling
32296183
Intra
MT1M Q8N339 KRTAP5-9 Homo sapiens P26371
Y2H Array
32296183
Intra
MT1M Q8N339 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
Intra
MT1M Q8N339 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra
MT1M Q8N339 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
MT1M Q8N339 SMCP Homo sapiens P49901
Y2H Array
32296183
Intra
MT1M Q8N339 SMCP Homo sapiens P49901
Y2H Prey Pooling
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Deficiency Anemia

  • Anemia

  • Deficiency Anemias

  • Anaemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08741 MT1M Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MT1M MGD MGI:97171