1 Result for "

387264

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "387264" in MCE Product Catalog:

Cat. No.: HY-184379
CAS No.: 2358714-71-1
Target:  

HIV

Research Areas:  

Infection

SRI-37264 is a HIV-1 Nef inhibitor with a Kd value of 162 nM. SRI-37264 binds directly to HIV-1 Nef, disrupts the Nef·MHC-I·AP-1 μ1 complex, and inhibits the Nef-dependent enhancement of HIV-1 infectivity. SRI-37264 restores MHC-I expression on the surface of HIV-infected primary cells. SRI-37264 inhibits HIV-1 replication in primary macrophages. SRI-37264 is applicable to research related to HIV-1 infection .
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