CIB4 - calcium and integrin binding family member 4 Gene

Also Known as KIP4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 130106

About CIB4

Cytogenetic location: 2p23.3 Genomic coordinates (GRCh38): 2:26,581,205-26,641,366 (from NCBI)

This gene has 3 transcripts (splice variants), 112 orthologues and 8 paralogues. Low expression observed in reference dataset.

Summary

Enables calcium ion binding activity and magnesium ion binding activity. [provided by Alliance of Genome Resources, Apr 2022]

CIB4 Products (1)

mRNA Protein Name
NM_001029881.3 NP_001025052.1 calcium and integrin-binding family member 4

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding IDA
IDA: Inferred from direct assay
22779914 GOA
enables magnesium ion binding IDA
IDA: Inferred from direct assay
22779914 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
22779914 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CIB4 Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (102 - 168)

  • 0
  • 100
  • 185 a.a.
Protein Preferred Names Protein Names

calcium and integrin-binding family member 4

CIB4 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
CIB4 A0PJX0 CREB5 Homo sapiens Q02930-3
Validated Y2H
32296183
Intra
CIB4 A0PJX0 VASN Homo sapiens Q6EMK4
Validated Y2H
32296183
Intra
CIB4 A0PJX0 ATG9A Homo sapiens Q7Z3C6-3
Validated Y2H
32296183
Intra
CIB4 A0PJX0 MYPOP Homo sapiens Q86VE0
Validated Y2H
32296183
Intra
CIB4 A0PJX0 TXN2 Homo sapiens Q99757
Validated Y2H
32296183
Intra
CIB4 A0PJX0 ZBTB9 Homo sapiens Q96C00
Validated Y2H
32296183
Intra
CIB4 A0PJX0 UBB Homo sapiens P0CG47
Anti Tag CoIP
28514442
Intra
CIB4 A0PJX0 UBB Homo sapiens P0CG47
Anti Tag CoIP
33961781
Intra
CIB4 A0PJX0 TACO1 Homo sapiens Q9BSH4
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Usher Syndrome, Type Ij

  • Usher Syndrome Type 1j

  • USH1J

  • Usher Syndrome Type Ij

  • Usher Syndrome 1j

  • Usher'S Syndrome Type 1j
Gingival Hypertrophy

  • Hypertrophy Of Gingivae
Gingival Fibromatosis

  • Hereditary Gingival Fibromatosis

  • Hereditary Gingival Hyperplasia

  • Autosomal Dominant Gingival Fibromatosis

  • Autosomal Dominant Gingival Hyperplasia

  • Fibromatosis, Gingival, Hereditary

  • Fibromatosis, Gingival
Usher Syndrome, Type I

  • USH1

  • Usher Syndrome Type 1

  • Us1

  • Usher Syndrome, Type 1b

  • Usher Syndrome Type 1e

  • Retinitis Pigmentosa And Congenital Deafness

  • Usher Syndrome, Type Ie

  • USH1E

  • Usher Syndrome, Type 1e

  • Usher Syndrome, Type 1a

  • Usher Syndrome, Type Ib

  • Usher Syndrome Type 1b

  • Usher Syndrome Type Ie

  • Usher Syndrome Type I

  • Usher 1

  • Usher Syndrome, Type 1

  • Ush1a

  • Usher Syndrome, Type I, French Variety

  • Usher Syndrome, Type Ia

  • Usher Syndrome 1b

  • USH1B

  • Usher'S Syndrome Type 1b

  • Usher Syndrome Type Ib

  • Ushib
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02709 CIB4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CIB4 VGNC VGNC:27362
Rattus norvegicus CIB4 RGD RGD:1584147
Mus musculus CIB4 MGD MGI:1920509
Macaca mulatta CIB4 VGNC VGNC:71379
Canis familiaris CIB4 VGNC VGNC:39269
Felis catus CIB4 VGNC VGNC:60899
Others CIB4 NCBI